526PTrial design and rationale for OPAL, a phase 2, randomized, double-blind study of apitegromab in patients aged <2 years with spinal muscular atrophy.

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Title: 526PTrial design and rationale for OPAL, a phase 2, randomized, double-blind study of apitegromab in patients aged <2 years with spinal muscular atrophy.
Authors: Servais, L.1,2 (AUTHOR), Crawford, T.3 (AUTHOR), Capocelli, K.4 (AUTHOR), Yao, B.4 (AUTHOR), Tirucherai, G.4 (AUTHOR), Xu, Y.4 (AUTHOR), Zhao, G.4 (AUTHOR), Marantz, J.4 (AUTHOR), Darras, B.5 (AUTHOR)
Source: Neuromuscular Disorders. 2025 Supplement, Vol. 53, pN.PAG-N.PAG. 1p.
Database: Academic Search Ultimate
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  Data: 526PTrial design and rationale for OPAL, a phase 2, randomized, double-blind study of apitegromab in patients aged &lt;2 years with spinal muscular atrophy.
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  Data: &lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Servais%2C+L%2E%22&quot;&gt;Servais, L.&lt;/searchLink&gt;&lt;relatesTo&gt;1,2&lt;/relatesTo&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Crawford%2C+T%2E%22&quot;&gt;Crawford, T.&lt;/searchLink&gt;&lt;relatesTo&gt;3&lt;/relatesTo&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Capocelli%2C+K%2E%22&quot;&gt;Capocelli, K.&lt;/searchLink&gt;&lt;relatesTo&gt;4&lt;/relatesTo&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Yao%2C+B%2E%22&quot;&gt;Yao, B.&lt;/searchLink&gt;&lt;relatesTo&gt;4&lt;/relatesTo&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Tirucherai%2C+G%2E%22&quot;&gt;Tirucherai, G.&lt;/searchLink&gt;&lt;relatesTo&gt;4&lt;/relatesTo&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Xu%2C+Y%2E%22&quot;&gt;Xu, Y.&lt;/searchLink&gt;&lt;relatesTo&gt;4&lt;/relatesTo&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Zhao%2C+G%2E%22&quot;&gt;Zhao, G.&lt;/searchLink&gt;&lt;relatesTo&gt;4&lt;/relatesTo&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Marantz%2C+J%2E%22&quot;&gt;Marantz, J.&lt;/searchLink&gt;&lt;relatesTo&gt;4&lt;/relatesTo&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Darras%2C+B%2E%22&quot;&gt;Darras, B.&lt;/searchLink&gt;&lt;relatesTo&gt;5&lt;/relatesTo&gt; (AUTHOR)
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  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22Neuromuscular+Disorders%22&quot;&gt;Neuromuscular Disorders&lt;/searchLink&gt;. 2025 Supplement, Vol. 53, pN.PAG-N.PAG. 1p.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=193863054
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      – Type: doi
        Value: 10.1016/j.nmd.2025.105615
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      – Code: eng
        Text: English
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      – TitleFull: 526PTrial design and rationale for OPAL, a phase 2, randomized, double-blind study of apitegromab in patients aged <2 years with spinal muscular atrophy.
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            – D: 02
              M: 09
              Text: 2025 Supplement
              Type: published
              Y: 2025
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              Value: 53
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            – TitleFull: Neuromuscular Disorders
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