Dual-function enzyme acts as a global c-di-GMP sink and local anti sigma factor antagonist to drive cellular differentiation. - Cınar Cakmak, Buse; Saric, Johanna D.; Wrede, Katrin; Holmes, Neil A.; Haist, Julian; Schumacher, Maria A.; Buttner, Mark J.; Tschowri, Natalia (PLoS Genetics, 2026)