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Bioinspired oxidized mRNA lipid nanoparticles for ex vivo engineering of chimeric antigen receptor macrophages targeting solid tumors.

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Title: Bioinspired oxidized mRNA lipid nanoparticles for ex vivo engineering of chimeric antigen receptor macrophages targeting solid tumors.
Authors: Mukalel, Alvin J.1 (AUTHOR), Tylek, Tina2 (AUTHOR), Geisler, Hannah C.1 (AUTHOR), O'Brien, Erin2 (AUTHOR), Frazee, Caitlin1 (AUTHOR), Li, Jacqueline1 (AUTHOR), Thatte, Ajay S.1 (AUTHOR), Safford, Hannah C.1 (AUTHOR), Figueroa‐Espada, Christian G.1 (AUTHOR), Alameh, Mohamad‐Gabriel3 (AUTHOR), Hamilton, Alex G.1 (AUTHOR), Mai, David1,4,5 (AUTHOR), Sheppard, Neil C.4,5,6 (AUTHOR), June, Carl H.4,5,6 (AUTHOR), Weissman, Drew3,4 (AUTHOR), Spiller, Kara L.2 (AUTHOR), Mitchell, Michael J.1,4,7,8,9,10,11 (AUTHOR) mjmitch@seas.upenn.edu
Source: Bioengineering & Translational Medicine. May2026, Vol. 11 Issue 3, p1-22. 22p.
Database: Academic Search Ultimate
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  Data: Bioinspired oxidized mRNA lipid nanoparticles for ex vivo engineering of chimeric antigen receptor macrophages targeting solid tumors.
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              Text: May2026
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