Higher frequency of subclonal anti-EGFR resistance mutations in post-treatment samples from patients with colorectal cancer liver metastases following anti-EGFR-based conversion chemotherapy.

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Title: Higher frequency of subclonal anti-EGFR resistance mutations in post-treatment samples from patients with colorectal cancer liver metastases following anti-EGFR-based conversion chemotherapy.
Authors: Steup, Christoph1 (AUTHOR) steup@med.uni-frankfurt.de, Mondorf, Antonia1 (AUTHOR), Wild, Peter2 (AUTHOR), Pession, Ursula3 (AUTHOR), Bechstein, Wolf Otto3 (AUTHOR), Michael, Florian A.1 (AUTHOR), Winter, Melanie2 (AUTHOR), Bein, Julia2 (AUTHOR), Zeuzem, Stefan1 (AUTHOR), Trojan, Jörg1 (AUTHOR), Koch, Christine1 (AUTHOR)
Source: PLoS ONE. 7/6/2026, Vol. 21 Issue 7, p1-17. 17p.
Database: Academic Search Ultimate
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ISSN:19326203
DOI:10.1371/journal.pone.0351243