12-HHT is associated with epithelial barrier enhancement and reduced inflammatory responses in colon organoids of normoganglionosis in Hirschsprung's disease. - Suda, Kazuto; Abe, Kumpei; Nishimura, Yurina; Tanaka, Masafumi; Nagasako, Yuki; Rao, Xuxuan; Zhang, Jianqin; Zeng, Siyi; Fujiwara, Kentaro; Yamada, Shunsuke; Ishii, Junya; Yoshida, Shiho; et al. (PLoS ONE, 2026)