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Acquired TSC1 Mutation as a Mechanism of Alectinib Resistance in ALK -Fused Leiomyosarcoma: Response to Combined ALK and Mammalian Target of Rapamycin Inhibition.

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Title: Acquired TSC1 Mutation as a Mechanism of Alectinib Resistance in ALK -Fused Leiomyosarcoma: Response to Combined ALK and Mammalian Target of Rapamycin Inhibition.
Authors: Posner, Alisa1 (AUTHOR), Rosenberg, Carol2 (AUTHOR), Esselen, Katharine M.3,4 (AUTHOR), Kelly, Andrew5 (AUTHOR), Bockorny, Bruno4,6 (AUTHOR) bbockorn@bidmc.harvard.edu
Source: JCO Precision Oncology. 7/23/2026, Vol. 10, p1-6. 6p.
Database: Academic Search Ultimate
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  Availability: 0
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DbLabel: Academic Search Ultimate
An: 195595801
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Data: Acquired TSC1 Mutation as a Mechanism of Alectinib Resistance in ALK -Fused Leiomyosarcoma: Response to Combined ALK and Mammalian Target of Rapamycin Inhibition.
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  Data: <searchLink fieldCode="AR" term="%22Posner%2C+Alisa%22">Posner, Alisa</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Rosenberg%2C+Carol%22">Rosenberg, Carol</searchLink><relatesTo>2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Esselen%2C+Katharine+M%2E%22">Esselen, Katharine M.</searchLink><relatesTo>3,4</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kelly%2C+Andrew%22">Kelly, Andrew</searchLink><relatesTo>5</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Bockorny%2C+Bruno%22">Bockorny, Bruno</searchLink><relatesTo>4,6</relatesTo> (AUTHOR)<i> bbockorn@bidmc.harvard.edu</i>
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  Data: <searchLink fieldCode="JN" term="%22JCO+Precision+Oncology%22">JCO Precision Oncology</searchLink>. 7/23/2026, Vol. 10, p1-6. 6p.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=195595801
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        Value: 10.1200/PO-26-00046
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      – Code: eng
        Text: English
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        PageCount: 6
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      – TitleFull: Acquired TSC1 Mutation as a Mechanism of Alectinib Resistance in ALK -Fused Leiomyosarcoma: Response to Combined ALK and Mammalian Target of Rapamycin Inhibition.
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            NameFull: Posner, Alisa
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            NameFull: Rosenberg, Carol
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            NameFull: Esselen, Katharine M.
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            NameFull: Kelly, Andrew
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            – D: 23
              M: 07
              Text: 7/23/2026
              Type: published
              Y: 2026
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