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Discovery of novel hydroxy-thiazoles as HIF-α prolyl hydroxylase inhibitors: SAR, synthesis, and modeling evaluation

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Title: Discovery of novel hydroxy-thiazoles as HIF-α prolyl hydroxylase inhibitors: SAR, synthesis, and modeling evaluation
Authors: Tegley, Christopher M.1 ctegley@amgen.com, Viswanadhan, Vellarkad N.1, Biswas, Kaustav1, Frohn, Michael J.1, Peterkin, Tanya A.N.1, Chang, Catherine1, Bürli, Roland W.1, Dao, Jennifer H.1, Veith, Henrike2, Rogers, Norma2, Yoder, Sean C.2, Biddlecome, Gloria2, Tagari, Philip1, Allen, Jennifer R.1, Hungate, Randall W.1
Source: Bioorganic & Medicinal Chemistry Letters. Jul2008, Vol. 18 Issue 14, p3925-3928. 4p.
Database: Academic Search Ultimate
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An: 33343318
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PubType: Academic Journal
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  Data: <searchLink fieldCode="JN" term="%22Bioorganic+%26+Medicinal+Chemistry+Letters%22">Bioorganic & Medicinal Chemistry Letters</searchLink>. Jul2008, Vol. 18 Issue 14, p3925-3928. 4p.
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        Value: 10.1016/j.bmcl.2008.06.031
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        Text: English
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              Text: Jul2008
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