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Utilization of in vitro Caco-2 permeability and liver microsomal half-life screens in discovering BMS-488043, a novel HIV-1 attachment inhibitor with improved pharmacokinetic properties.

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Title: Utilization of in vitro Caco-2 permeability and liver microsomal half-life screens in discovering BMS-488043, a novel HIV-1 attachment inhibitor with improved pharmacokinetic properties.
Authors: Zheng Yang1 yangz@bms.com, Zadjura, Lisa M.1, Marino, Anthony M.1, D'Arienzo, Celia J.2, Malinowski, Jacek2, Gesenberg, Christoph3, Pin-Fang Lin4, Colonno, Richard J.4, Tao Wang5, Kadow, John F.5, Meanwell, Nicholas A.5, Hansel, Steven B.6
Source: Journal of Pharmaceutical Sciences. Apr2010, Vol. 99 Issue 4, p2135-2152. 18p. 1 Diagram, 3 Charts, 4 Graphs.
Database: Academic Search Ultimate
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Pharmaceutical+Sciences%22">Journal of Pharmaceutical Sciences</searchLink>. Apr2010, Vol. 99 Issue 4, p2135-2152. 18p. 1 Diagram, 3 Charts, 4 Graphs.
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              Text: Apr2010
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