Utilization of in vitro Caco-2 permeability and liver microsomal half-life screens in discovering BMS-488043, a novel HIV-1 attachment inhibitor with improved pharmacokinetic properties.
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| Title: | Utilization of in vitro Caco-2 permeability and liver microsomal half-life screens in discovering BMS-488043, a novel HIV-1 attachment inhibitor with improved pharmacokinetic properties. |
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| Authors: | Zheng Yang1 yangz@bms.com, Zadjura, Lisa M.1, Marino, Anthony M.1, D'Arienzo, Celia J.2, Malinowski, Jacek2, Gesenberg, Christoph3, Pin-Fang Lin4, Colonno, Richard J.4, Tao Wang5, Kadow, John F.5, Meanwell, Nicholas A.5, Hansel, Steven B.6 |
| Source: | Journal of Pharmaceutical Sciences. Apr2010, Vol. 99 Issue 4, p2135-2152. 18p. 1 Diagram, 3 Charts, 4 Graphs. |
| Database: | Academic Search Ultimate |
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