Design, synthesis and structure–activity relationships of (indo-3-yl) heterocyclic derivatives as agonists of the CB1 receptor. Discovery of a clinical candidate

Saved in:
Bibliographic Details
Title: Design, synthesis and structure–activity relationships of (indo-3-yl) heterocyclic derivatives as agonists of the CB1 receptor. Discovery of a clinical candidate
Authors: Ratcliffe, Paul1 Paul.Ratcliffe@grunenthal.com, Adam, Julia M.1, Baker, James2, Bursi, Roberta3, Campbell, Robert2, Clark, John K.1, Cottney, Jean E.2, Deehan, Maureen2, Easson, Anna-Marie1, Ecker, Daniel4, Edwards, Darren1, Epemolu, Ola2, Evans, Louise2, Fields, Ruth1, Francis, Stuart1, Harradine, Paul1, Jeremiah, Fiona1, Kiyoi, Takao1, McArthur, Duncan1, Morrison, Angus1
Source: Bioorganic & Medicinal Chemistry Letters. Apr2011, Vol. 21 Issue 8, p2541-2546. 6p.
Database: Academic Search Ultimate
FullText Text:
  Availability: 0
Header DbId: asn
DbLabel: Academic Search Ultimate
An: 59773415
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Design, synthesis and structure–activity relationships of (indo-3-yl) heterocyclic derivatives as agonists of the CB1 receptor. Discovery of a clinical candidate
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Ratcliffe%2C+Paul%22">Ratcliffe, Paul</searchLink><relatesTo>1</relatesTo><i> Paul.Ratcliffe@grunenthal.com</i><br /><searchLink fieldCode="AR" term="%22Adam%2C+Julia+M%2E%22">Adam, Julia M.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Baker%2C+James%22">Baker, James</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Bursi%2C+Roberta%22">Bursi, Roberta</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Campbell%2C+Robert%22">Campbell, Robert</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Clark%2C+John+K%2E%22">Clark, John K.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Cottney%2C+Jean+E%2E%22">Cottney, Jean E.</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Deehan%2C+Maureen%22">Deehan, Maureen</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Easson%2C+Anna-Marie%22">Easson, Anna-Marie</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Ecker%2C+Daniel%22">Ecker, Daniel</searchLink><relatesTo>4</relatesTo><br /><searchLink fieldCode="AR" term="%22Edwards%2C+Darren%22">Edwards, Darren</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Epemolu%2C+Ola%22">Epemolu, Ola</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Evans%2C+Louise%22">Evans, Louise</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Fields%2C+Ruth%22">Fields, Ruth</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Francis%2C+Stuart%22">Francis, Stuart</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Harradine%2C+Paul%22">Harradine, Paul</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Jeremiah%2C+Fiona%22">Jeremiah, Fiona</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Kiyoi%2C+Takao%22">Kiyoi, Takao</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22McArthur%2C+Duncan%22">McArthur, Duncan</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Morrison%2C+Angus%22">Morrison, Angus</searchLink><relatesTo>1</relatesTo>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Bioorganic+%26+Medicinal+Chemistry+Letters%22">Bioorganic & Medicinal Chemistry Letters</searchLink>. Apr2011, Vol. 21 Issue 8, p2541-2546. 6p.
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=asn&AN=59773415
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/j.bmcl.2011.02.023
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 6
        StartPage: 2541
    Titles:
      – TitleFull: Design, synthesis and structure–activity relationships of (indo-3-yl) heterocyclic derivatives as agonists of the CB1 receptor. Discovery of a clinical candidate
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Ratcliffe, Paul
      – PersonEntity:
          Name:
            NameFull: Adam, Julia M.
      – PersonEntity:
          Name:
            NameFull: Baker, James
      – PersonEntity:
          Name:
            NameFull: Bursi, Roberta
      – PersonEntity:
          Name:
            NameFull: Campbell, Robert
      – PersonEntity:
          Name:
            NameFull: Clark, John K.
      – PersonEntity:
          Name:
            NameFull: Cottney, Jean E.
      – PersonEntity:
          Name:
            NameFull: Deehan, Maureen
      – PersonEntity:
          Name:
            NameFull: Easson, Anna-Marie
      – PersonEntity:
          Name:
            NameFull: Ecker, Daniel
      – PersonEntity:
          Name:
            NameFull: Edwards, Darren
      – PersonEntity:
          Name:
            NameFull: Epemolu, Ola
      – PersonEntity:
          Name:
            NameFull: Evans, Louise
      – PersonEntity:
          Name:
            NameFull: Fields, Ruth
      – PersonEntity:
          Name:
            NameFull: Francis, Stuart
      – PersonEntity:
          Name:
            NameFull: Harradine, Paul
      – PersonEntity:
          Name:
            NameFull: Jeremiah, Fiona
      – PersonEntity:
          Name:
            NameFull: Kiyoi, Takao
      – PersonEntity:
          Name:
            NameFull: McArthur, Duncan
      – PersonEntity:
          Name:
            NameFull: Morrison, Angus
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 15
              M: 04
              Text: Apr2011
              Type: published
              Y: 2011
          Identifiers:
            – Type: issn-print
              Value: 0960894X
          Numbering:
            – Type: volume
              Value: 21
            – Type: issue
              Value: 8
          Titles:
            – TitleFull: Bioorganic & Medicinal Chemistry Letters
              Type: main
ResultId 1