E258K HCM-causing mutatio n in cardiac MyBP-C reduces contractile force and accelerates twitch kinetics by disrupting the cMyBP-C and myosin S2 interaction.
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| Title: | E258K HCM-causing mutatio n in cardiac MyBP-C reduces contractile force and accelerates twitch kinetics by disrupting the cMyBP-C and myosin S2 interaction. |
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| Authors: | De Lange, Willem J.1, Grimes, Adrian C.1, Hegge, Laura F.1, Spring, Alexander M.1, Brost, Taylor M.1, Ralphe, J. Carter1 jcralplie@pediatrics.wisc.edu |
| Source: | Journal of General Physiology. Sep2013, Vol. 142 Issue 3, p241-255. 15p. |
| Database: | Academic Search Ultimate |
| ISSN: | 00221295 |
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| DOI: | 10.1085/jgp.201311018 |
