Bayesian belief networks for dementia diagnosis and other applications : a comparison of hand-crafting and construction using a novel data driven technique
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| Title: | Bayesian belief networks for dementia diagnosis and other applications : a comparison of hand-crafting and construction using a novel data driven technique |
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| Authors: | Oteniya, Lloyd |
| Committee Members: | Cowie, Julie; Smith, Leslie S. |
| Summary: | The Bayesian network (BN) formalism is a powerful representation for encoding domains characterised by uncertainty. However, before it can be used it must first be constructed, which is a major challenge for any real-life problem. There are two broad approaches, namely the hand-crafted approach, which relies on a human expert, and the data-driven approach, which relies on data. The former approach is useful, however issues such as human bias can introduce errors into the model. We have conducted a literature review of the expert-driven approach, and we have cherry-picked a number of common methods, and engineered a framework to assist non-BN experts with expert-driven construction of BNs. The latter construction approach uses algorithms to construct the model from a data set. However, construction from data is provably NP-hard. To solve this problem, approximate, heuristic algorithms have been proposed; in particular, algorithms that assume an order between the nodes, therefore reducing the search space. However, traditionally, this approach relies on an expert providing the order among the variables --- an expert may not always be available, or may be unable to provide the order. Nevertheless, if a good order is available, these order-based algorithms have demonstrated good performance. More recent approaches attempt to ''learn'' a good order then use the order-based algorithm to discover the structure. To eliminate the need for order information during construction, we propose a search in the entire space of Bayesian network structures --- we present a novel approach for carrying out this task, and we demonstrate its performance against existing algorithms that search in the entire space and the space of orders. Finally, we employ the hand-crafting framework to construct models for the task of diagnosis in a ''real-life'' medical domain, dementia diagnosis. We collect real dementia data from clinical practice, and we apply the data-driven algorithms developed to assess the concordance between the reference models developed by hand and the models derived from real clinical data. |
| URL: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.513782 |
| Database: | OpenDissertations |
| FullText | Text: Availability: 0 |
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| Header | DbId: ddu DbLabel: OpenDissertations An: ddu.oai.ethos.bl.uk.513782 AccessLevel: 6 PubType: Dissertation/ Thesis PubTypeId: dissertation PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Bayesian belief networks for dementia diagnosis and other applications : a comparison of hand-crafting and construction using a novel data driven technique – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Oteniya%2C+Lloyd%22">Oteniya, Lloyd</searchLink> – Name: Author Label: Committee Members Group: Au Data: <searchLink fieldCode="CO" term="%22Cowie%2C+Julie%22">Cowie, Julie</searchLink>; <searchLink fieldCode="CO" term="%22Smith%2C+Leslie+S%2E%22">Smith, Leslie S.</searchLink> – Name: Abstract Label: Summary Group: Ab Data: The Bayesian network (BN) formalism is a powerful representation for encoding domains characterised by uncertainty. However, before it can be used it must first be constructed, which is a major challenge for any real-life problem. There are two broad approaches, namely the hand-crafted approach, which relies on a human expert, and the data-driven approach, which relies on data. The former approach is useful, however issues such as human bias can introduce errors into the model. We have conducted a literature review of the expert-driven approach, and we have cherry-picked a number of common methods, and engineered a framework to assist non-BN experts with expert-driven construction of BNs. The latter construction approach uses algorithms to construct the model from a data set. However, construction from data is provably NP-hard. To solve this problem, approximate, heuristic algorithms have been proposed; in particular, algorithms that assume an order between the nodes, therefore reducing the search space. However, traditionally, this approach relies on an expert providing the order among the variables --- an expert may not always be available, or may be unable to provide the order. Nevertheless, if a good order is available, these order-based algorithms have demonstrated good performance. More recent approaches attempt to ''learn'' a good order then use the order-based algorithm to discover the structure. To eliminate the need for order information during construction, we propose a search in the entire space of Bayesian network structures --- we present a novel approach for carrying out this task, and we demonstrate its performance against existing algorithms that search in the entire space and the space of orders. Finally, we employ the hand-crafting framework to construct models for the task of diagnosis in a ''real-life'' medical domain, dementia diagnosis. We collect real dementia data from clinical practice, and we apply the data-driven algorithms developed to assess the concordance between the reference models developed by hand and the models derived from real clinical data. – Name: URL Label: URL Group: URL Data: <link linkTarget="URL" linkTerm="http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.513782" linkWindow="_blank">http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.513782</link> |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=ddu&AN=ddu.oai.ethos.bl.uk.513782 |
| RecordInfo | BibRecord: BibEntity: Languages: – Code: eng Text: English Subjects: – SubjectFull: 519.5 Type: general – SubjectFull: Bayesian networks : Bayesian network learning : Particle Swarm Optimisation : Dementia : Dementia diagnosis : Alzheimer's disease : Applications of Bayesian networks : Hand-crafting Bayesian networks : Expert-driven Bayesian networks : Constructing Bayesian networks : Bayesian statistical decision theory Data processing : Dementia Research Statistical methods : Dementia Diagnosis Type: general Titles: – TitleFull: Bayesian belief networks for dementia diagnosis and other applications : a comparison of hand-crafting and construction using a novel data driven technique Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Oteniya, Lloyd IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Type: published Y: 2008 |
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