Random coeffcient models for complex longitudinal data

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Title: Random coeffcient models for complex longitudinal data
Authors: Kidney, Darren
Committee Members: Donovan, Carl Robert; MacKenzie, Monique Lea
Summary: Longitudinal data are common in biological research. However, real data sets vary considerably in terms of their structure and complexity and present many challenges for statistical modelling. This thesis proposes a series of methods using random coefficients for modelling two broad types of longitudinal response: normally distributed measurements and binary recapture data. Biased inference can occur in linear mixed-effects modelling if subjects are drawn from a number of unknown sub-populations, or if the residual covariance is poorly specified. To address some of the shortcomings of previous approaches in terms of model selection and flexibility, this thesis presents methods for: (i) determining the presence of latent grouping structures using a two-step approach, involving regression splines for modelling functional random effects and mixture modelling of the fitted random effects; and (ii) flexible of modelling of the residual covariance matrix using regression splines to specify smooth and potentially non-monotonic variance and correlation functions. Spatially explicit capture-recapture methods for estimating the density of animal populations have shown a rapid increase in popularity over recent years. However, further refinements to existing theory and fitting software are required to apply these methods in many situations. This thesis presents: (i) an analysis of recapture data from an acoustic survey of gibbons using supplementary data in the form of estimated angles to detections, (ii) the development of a multi-occasion likelihood including a model for stochastic availability using a partially observed random effect (interpreted in terms of calling behaviour in the case of gibbons), and (iii) an analysis of recapture data from a population of radio-tagged skates using a conditional likelihood that allows the density of animal activity centres to be modelled as functions of time, space and animal-level covariates.
URL: http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.644817
Database: OpenDissertations
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Header DbId: ddu
DbLabel: OpenDissertations
An: ddu.oai.ethos.bl.uk.644817
AccessLevel: 6
PubType: Dissertation/ Thesis
PubTypeId: dissertation
PreciseRelevancyScore: 0
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  Label: Title
  Group: Ti
  Data: Random coeffcient models for complex longitudinal data
– Name: Author
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  Data: <searchLink fieldCode="AR" term="%22Kidney%2C+Darren%22">Kidney, Darren</searchLink>
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  Data: <searchLink fieldCode="CO" term="%22Donovan%2C+Carl+Robert%22">Donovan, Carl Robert</searchLink>; <searchLink fieldCode="CO" term="%22MacKenzie%2C+Monique+Lea%22">MacKenzie, Monique Lea</searchLink>
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  Label: Summary
  Group: Ab
  Data: Longitudinal data are common in biological research. However, real data sets vary considerably in terms of their structure and complexity and present many challenges for statistical modelling. This thesis proposes a series of methods using random coefficients for modelling two broad types of longitudinal response: normally distributed measurements and binary recapture data. Biased inference can occur in linear mixed-effects modelling if subjects are drawn from a number of unknown sub-populations, or if the residual covariance is poorly specified. To address some of the shortcomings of previous approaches in terms of model selection and flexibility, this thesis presents methods for: (i) determining the presence of latent grouping structures using a two-step approach, involving regression splines for modelling functional random effects and mixture modelling of the fitted random effects; and (ii) flexible of modelling of the residual covariance matrix using regression splines to specify smooth and potentially non-monotonic variance and correlation functions. Spatially explicit capture-recapture methods for estimating the density of animal populations have shown a rapid increase in popularity over recent years. However, further refinements to existing theory and fitting software are required to apply these methods in many situations. This thesis presents: (i) an analysis of recapture data from an acoustic survey of gibbons using supplementary data in the form of estimated angles to detections, (ii) the development of a multi-occasion likelihood including a model for stochastic availability using a partially observed random effect (interpreted in terms of calling behaviour in the case of gibbons), and (iii) an analysis of recapture data from a population of radio-tagged skates using a conditional likelihood that allows the density of animal activity centres to be modelled as functions of time, space and animal-level covariates.
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RecordInfo BibRecord:
  BibEntity:
    Languages:
      – Code: eng
        Text: English
    Subjects:
      – SubjectFull: 519.5
        Type: general
      – SubjectFull: Random effects ; Mixed effects models ; Autocorrelation ; Spatially explicit capture-recapture ; SECR ; Availability ; QA278.K53 ; Multilevel models (Statistics) ; Autocorrelation (Statistics)
        Type: general
    Titles:
      – TitleFull: Random coeffcient models for complex longitudinal data
        Type: main
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      – PersonEntity:
          Name:
            NameFull: Kidney, Darren
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      – BibEntity:
          Dates:
            – D: 01
              M: 01
              Type: published
              Y: 2014
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