The Human Proteome Organization (HUPO) and Environmental Health.
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| Title: | The Human Proteome Organization (HUPO) and Environmental Health. |
|---|---|
| Authors: | Merrick, B. Alex |
| Source: | Environmental Health Perspectives. May2003 Toxicogenomics, Vol. 111 Issue 6, p797. 5p. |
| Subjects: | Proteomics, Environmental health, Biological societies |
| Abstract: | The Human Proteome Organization, or HUPO, was formed to promote research and large-scale analysis of the human proteome. By consolidating national proteome organizations into an international body, HUPO will coordinate international initiatives, biological resources, protocols, standards and data for studying the human proteome. HUPO has identified five key areas to advance study of the human proteome, specifically in bioinformatics, new technologies, the plasma proteome, cell models, and a public antibody initiative. Consideration of three major issue areas may help develop HUPO's strategy for human proteome study. First is the need to distinguish the value of high throughput platforms from discovery platforms in proteomics. Second is the importance for international planning on integrating both transcriptome and proteome data and databases. Last is that effects of the environment from chemical, physical, and biological exposures alter the expression and structure of the proteome, which become manifest in longterm adverse health effects and disease. Environmental health research stands to greatly benefit from the shared resources, data, and vision of the HUPO organization as a valuable resource in exploiting knowledge of the human proteome toward improving public health. [ABSTRACT FROM AUTHOR] |
| Copyright of Environmental Health Perspectives is the property of National Institute of Environmental Health Sciences and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 10036365 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: The Human Proteome Organization (HUPO) and Environmental Health. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Merrick%2C+B%2E+Alex%22">Merrick, B. Alex</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Environmental+Health+Perspectives%22">Environmental Health Perspectives</searchLink>. May2003 Toxicogenomics, Vol. 111 Issue 6, p797. 5p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Proteomics%22">Proteomics</searchLink><br /><searchLink fieldCode="DE" term="%22Environmental+health%22">Environmental health</searchLink><br /><searchLink fieldCode="DE" term="%22Biological+societies%22">Biological societies</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: The Human Proteome Organization, or HUPO, was formed to promote research and large-scale analysis of the human proteome. By consolidating national proteome organizations into an international body, HUPO will coordinate international initiatives, biological resources, protocols, standards and data for studying the human proteome. HUPO has identified five key areas to advance study of the human proteome, specifically in bioinformatics, new technologies, the plasma proteome, cell models, and a public antibody initiative. Consideration of three major issue areas may help develop HUPO's strategy for human proteome study. First is the need to distinguish the value of high throughput platforms from discovery platforms in proteomics. Second is the importance for international planning on integrating both transcriptome and proteome data and databases. Last is that effects of the environment from chemical, physical, and biological exposures alter the expression and structure of the proteome, which become manifest in longterm adverse health effects and disease. Environmental health research stands to greatly benefit from the shared resources, data, and vision of the HUPO organization as a valuable resource in exploiting knowledge of the human proteome toward improving public health. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Environmental Health Perspectives is the property of National Institute of Environmental Health Sciences and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=10036365 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1289/ehp.111-1241501 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 5 StartPage: 797 Subjects: – SubjectFull: Proteomics Type: general – SubjectFull: Environmental health Type: general – SubjectFull: Biological societies Type: general Titles: – TitleFull: The Human Proteome Organization (HUPO) and Environmental Health. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Merrick, B. Alex IsPartOfRelationships: – BibEntity: Dates: – D: 15 M: 05 Text: May2003 Toxicogenomics Type: published Y: 2003 Identifiers: – Type: issn-print Value: 00916765 Numbering: – Type: volume Value: 111 – Type: issue Value: 6 Titles: – TitleFull: Environmental Health Perspectives Type: main |
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