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Links between mechanical behavior of cancellous bone and its microstructural properties under dynamic loading.

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Title: Links between mechanical behavior of cancellous bone and its microstructural properties under dynamic loading.
Authors: Prot, M.1 marianne.prot@ensam.eu, Saletti, D.1,2, Pattofattoc, S.3, Bousson, V.4, Laporte, S.1
Source: Journal of Biomechanics. 2015, Vol. 48 Issue 3, p498-503. 6p.
Subjects: Biomechanics, Dynamic loads, Microstructure, Cancellous bone, Bone mechanics, Boundary value problems
Abstract: Previous studies show that in vivo assessment of fracture risk can be achieved by identifying the relationships between microarchitecture description from clinical imaging and mechanical properties. This study demonstrates that results obtained at low strain rates can be extrapolated to loadings with an order of magnitude similar to trauma such as car crashes. Cancellous bovine bone specimens were compressed under dynamic loadings (with and without confinement) and the mechanical response properties were identified, such as Young's modulus, ultimate stress, ultimate strain, and ultimate strain energy. Specimens were previously scanned with pQCT, and architectural and structural microstructure properties were identified, such as parameters of geometry, topology, connectivity and anisotropy. The usefulness of micro-architecture description studied was in agreement with statistics laws. Finally, the differences between dynamic confined and non-confined tests were assessed by the bone marrow influence and the cancellous bone response to different boundary conditions. Results indicate that architectural parameters, such as the bone volume fraction (BV/TV), are as strong determinants of mechanical response parameters as ultimate stress at high strain rates (p-value < 0.001). This study reveals that cancellous bone response at high strain rates, under different boundary conditions, can be predicted from the architectural parameters, and that these relations with mechanical properties can be used to make fracture risk prediction at a determined magnitude [ABSTRACT FROM AUTHOR]
Copyright of Journal of Biomechanics is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Links between mechanical behavior of cancellous bone and its microstructural properties under dynamic loading.
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  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22Journal+of+Biomechanics%22&quot;&gt;Journal of Biomechanics&lt;/searchLink&gt;. 2015, Vol. 48 Issue 3, p498-503. 6p.
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  Data: Previous studies show that in vivo assessment of fracture risk can be achieved by identifying the relationships between microarchitecture description from clinical imaging and mechanical properties. This study demonstrates that results obtained at low strain rates can be extrapolated to loadings with an order of magnitude similar to trauma such as car crashes. Cancellous bovine bone specimens were compressed under dynamic loadings (with and without confinement) and the mechanical response properties were identified, such as Young&#39;s modulus, ultimate stress, ultimate strain, and ultimate strain energy. Specimens were previously scanned with pQCT, and architectural and structural microstructure properties were identified, such as parameters of geometry, topology, connectivity and anisotropy. The usefulness of micro-architecture description studied was in agreement with statistics laws. Finally, the differences between dynamic confined and non-confined tests were assessed by the bone marrow influence and the cancellous bone response to different boundary conditions. Results indicate that architectural parameters, such as the bone volume fraction (BV/TV), are as strong determinants of mechanical response parameters as ultimate stress at high strain rates (p-value &lt; 0.001). This study reveals that cancellous bone response at high strain rates, under different boundary conditions, can be predicted from the architectural parameters, and that these relations with mechanical properties can be used to make fracture risk prediction at a determined magnitude [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of Journal of Biomechanics is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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        Value: 10.1016/j.jbiomech.2014.12.002
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      – Code: eng
        Text: English
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      Pagination:
        PageCount: 6
        StartPage: 498
    Subjects:
      – SubjectFull: Biomechanics
        Type: general
      – SubjectFull: Dynamic loads
        Type: general
      – SubjectFull: Microstructure
        Type: general
      – SubjectFull: Cancellous bone
        Type: general
      – SubjectFull: Bone mechanics
        Type: general
      – SubjectFull: Boundary value problems
        Type: general
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      – TitleFull: Links between mechanical behavior of cancellous bone and its microstructural properties under dynamic loading.
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            NameFull: Prot, M.
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            NameFull: Saletti, D.
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            NameFull: Pattofattoc, S.
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            NameFull: Bousson, V.
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              Text: 2015
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              Y: 2015
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