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A feasibility study of a PET/MRI insert detector using strip-line and waveform sampling data acquisition.

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Title: A feasibility study of a PET/MRI insert detector using strip-line and waveform sampling data acquisition.
Authors: Kim, H.1 heejongkim@uchicago.edu, Chen, C.-T.1, Eclov, N.1, Ronzhin, A.2, Murat, P.2, Ramberg, E.2, Los, S.2, Wyrwicz, A.M.3, Li, L.3, Kao, C.-M.1
Source: Nuclear Instruments & Methods in Physics Research Section A. Jun2015, Vol. 784, p557-564. 8p.
Subjects: Positron emission tomography, Feasibility studies, Photomultipliers, Wave analysis, Magnetic resonance imaging
Abstract: We are developing a time-of-flight Positron Emission Tomography (PET) detector by using silicon photo-multipliers (SiPM) on a strip-line and high speed waveform sampling data acquisition. In this design, multiple SiPMs are connected on a single strip-line and signal waveforms on the strip-line are sampled at two ends of the strip to reduce readout channels while fully exploiting the fast time response of SiPMs. In addition to the deposited energy and time information, the position of the hit SiPM along the strip-line is determined by the arrival time difference of the waveform. Due to the insensitivity of the SiPMs to magnetic fields and the compact front-end electronics, the detector approach is highly attractive for developing a PET insert system for a magnetic resonance imaging (MRI) scanner to provide simultaneous PET/MR imaging. To investigate the feasibility, experimental tests using prototype detector modules have been conducted inside a 9.4 T small animal MRI scanner (Bruker BioSpec 94/30 imaging spectrometer). On the prototype strip-line board, 16 SiPMs (5.2 mm pitch) are installed on two strip-lines and coupled to 2×8 LYSO scintillators (5.0×5.0×10.0 mm 3 with 5.2 mm pitch). The outputs of the strip-line boards are connected to a Domino-Ring-Sampler (DRS4) evaluation board for waveform sampling. Preliminary experimental results show that the effect of interference on the MRI image due to the PET detector is negligible and that PET detector performance is comparable with the results measured outside the MRI scanner. [ABSTRACT FROM AUTHOR]
Copyright of Nuclear Instruments & Methods in Physics Research Section A is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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DbLabel: Engineering Source
An: 102217896
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  Data: A feasibility study of a PET/MRI insert detector using strip-line and waveform sampling data acquisition.
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  Data: <searchLink fieldCode="AR" term="%22Kim%2C+H%2E%22">Kim, H.</searchLink><relatesTo>1</relatesTo><i> heejongkim@uchicago.edu</i><br /><searchLink fieldCode="AR" term="%22Chen%2C+C%2E-T%2E%22">Chen, C.-T.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Eclov%2C+N%2E%22">Eclov, N.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Ronzhin%2C+A%2E%22">Ronzhin, A.</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Murat%2C+P%2E%22">Murat, P.</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Ramberg%2C+E%2E%22">Ramberg, E.</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Los%2C+S%2E%22">Los, S.</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Wyrwicz%2C+A%2EM%2E%22">Wyrwicz, A.M.</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Li%2C+L%2E%22">Li, L.</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Kao%2C+C%2E-M%2E%22">Kao, C.-M.</searchLink><relatesTo>1</relatesTo>
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  Data: We are developing a time-of-flight Positron Emission Tomography (PET) detector by using silicon photo-multipliers (SiPM) on a strip-line and high speed waveform sampling data acquisition. In this design, multiple SiPMs are connected on a single strip-line and signal waveforms on the strip-line are sampled at two ends of the strip to reduce readout channels while fully exploiting the fast time response of SiPMs. In addition to the deposited energy and time information, the position of the hit SiPM along the strip-line is determined by the arrival time difference of the waveform. Due to the insensitivity of the SiPMs to magnetic fields and the compact front-end electronics, the detector approach is highly attractive for developing a PET insert system for a magnetic resonance imaging (MRI) scanner to provide simultaneous PET/MR imaging. To investigate the feasibility, experimental tests using prototype detector modules have been conducted inside a 9.4 T small animal MRI scanner (Bruker BioSpec 94/30 imaging spectrometer). On the prototype strip-line board, 16 SiPMs (5.2 mm pitch) are installed on two strip-lines and coupled to 2×8 LYSO scintillators (5.0×5.0×10.0 mm 3 with 5.2 mm pitch). The outputs of the strip-line boards are connected to a Domino-Ring-Sampler (DRS4) evaluation board for waveform sampling. Preliminary experimental results show that the effect of interference on the MRI image due to the PET detector is negligible and that PET detector performance is comparable with the results measured outside the MRI scanner. [ABSTRACT FROM AUTHOR]
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  Label:
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  Data: <i>Copyright of Nuclear Instruments & Methods in Physics Research Section A is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1016/j.nima.2014.12.080
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        Text: English
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        PageCount: 8
        StartPage: 557
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      – SubjectFull: Positron emission tomography
        Type: general
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      – SubjectFull: Wave analysis
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      – SubjectFull: Magnetic resonance imaging
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      – TitleFull: A feasibility study of a PET/MRI insert detector using strip-line and waveform sampling data acquisition.
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              Text: Jun2015
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