Lawsonia inermis L. – A commercially important primaeval dying and medicinal plant with diverse pharmacological activity: A review.

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Title: Lawsonia inermis L. – A commercially important primaeval dying and medicinal plant with diverse pharmacological activity: A review.
Authors: Singh, Dhananjay Kumar1, Luqman, Suaib1,2 s.luqman@cimap.res.in, Mathur, Ajay Kumar2,3
Source: Industrial Crops & Products. Mar2015, Vol. 65, p269-286. 18p.
Subjects: Henna (Plant), Medicinal plants, Pharmacology, Lythraceae, Antioxidants
Abstract: Lawsonia inermis , popularly known as Henna or Mehndi in the Oriental world, is an evergreen medium sized shrub of the Family Lythraceae. The leaf paste of this plant has been traditionally used for dying hair, skin and nails since antiquity. Besides cosmaceutical usages, the plant also harbours a well-documented folklore history for treating convulsion, jaundice and malignant ulcers. Phytochemical studies in henna plant have indicated the presence of several bioactive molecules like isoplumpagin, lupeol, 30-norlupan-3-ol-20-one, betuhennan, betuhennanic acid and n-tridecanoate phenolic glycosides, lawsoniaside, β-sitosterol and stigmasterol in leaves and roots. Lawsone (2-hydroxy-1,4-naphthoquinone), the red orange dye present in the henna leaf paste, is being used in modern pharmacopoeia as a starting molecule for the synthesis of clinically important anticancer drugs such as atovaquone, lapachol and dichloroallyl lawsone. Pharmacological prospection of L. inermis plant extracts in last two decades have indicated strong nootropic, CNS depressing, antimicrobial, antioxidant, wound healing, anti-inflammatory, antipyretic, analgesic, hepatoprotective, tuberculostatic, diuretic, hypoglycemic and antiparasitic actions. An attempt has been made in this review to accentuate a comprehensive literature up-date on pharmacological investigations carried out in L. inermis. To the best of our knowledge and belief this is the first compilation in this direction in Henna. [ABSTRACT FROM AUTHOR]
Copyright of Industrial Crops & Products is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Lawsonia inermis L. – A commercially important primaeval dying and medicinal plant with diverse pharmacological activity: A review.
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  Data: <searchLink fieldCode="JN" term="%22Industrial+Crops+%26+Products%22">Industrial Crops & Products</searchLink>. Mar2015, Vol. 65, p269-286. 18p.
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  Data: <searchLink fieldCode="DE" term="%22Henna+%28Plant%29%22">Henna (Plant)</searchLink><br /><searchLink fieldCode="DE" term="%22Medicinal+plants%22">Medicinal plants</searchLink><br /><searchLink fieldCode="DE" term="%22Pharmacology%22">Pharmacology</searchLink><br /><searchLink fieldCode="DE" term="%22Lythraceae%22">Lythraceae</searchLink><br /><searchLink fieldCode="DE" term="%22Antioxidants%22">Antioxidants</searchLink>
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  Data: Lawsonia inermis , popularly known as Henna or Mehndi in the Oriental world, is an evergreen medium sized shrub of the Family Lythraceae. The leaf paste of this plant has been traditionally used for dying hair, skin and nails since antiquity. Besides cosmaceutical usages, the plant also harbours a well-documented folklore history for treating convulsion, jaundice and malignant ulcers. Phytochemical studies in henna plant have indicated the presence of several bioactive molecules like isoplumpagin, lupeol, 30-norlupan-3-ol-20-one, betuhennan, betuhennanic acid and n-tridecanoate phenolic glycosides, lawsoniaside, β-sitosterol and stigmasterol in leaves and roots. Lawsone (2-hydroxy-1,4-naphthoquinone), the red orange dye present in the henna leaf paste, is being used in modern pharmacopoeia as a starting molecule for the synthesis of clinically important anticancer drugs such as atovaquone, lapachol and dichloroallyl lawsone. Pharmacological prospection of L. inermis plant extracts in last two decades have indicated strong nootropic, CNS depressing, antimicrobial, antioxidant, wound healing, anti-inflammatory, antipyretic, analgesic, hepatoprotective, tuberculostatic, diuretic, hypoglycemic and antiparasitic actions. An attempt has been made in this review to accentuate a comprehensive literature up-date on pharmacological investigations carried out in L. inermis. To the best of our knowledge and belief this is the first compilation in this direction in Henna. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
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  Data: <i>Copyright of Industrial Crops & Products is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1016/j.indcrop.2014.11.025
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        Text: English
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      – SubjectFull: Henna (Plant)
        Type: general
      – SubjectFull: Medicinal plants
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      – SubjectFull: Pharmacology
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      – SubjectFull: Lythraceae
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      – SubjectFull: Antioxidants
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              Text: Mar2015
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