Variability of average SUV from several hottest voxels is lower than that of SUVmax and SUVpeak.
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| Title: | Variability of average SUV from several hottest voxels is lower than that of SUVmax and SUVpeak. |
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| Authors: | Laffon, E (AUTHOR), Lamare, F (AUTHOR), de Clermont, H (AUTHOR), Burger, I A (AUTHOR), Marthan, R (AUTHOR) |
| Source: | European Radiology. Aug2014, Vol. 24 Issue 8, p1964-1970. 7p. |
| Abstract: | |
| Copyright of European Radiology is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| URL: | 103832326 |
| Database: | Engineering Source |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 103832326 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Variability of average SUV from several hottest voxels is lower than that of SUVmax and SUVpeak. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Laffon%2C+E%22">Laffon, E</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lamare%2C+F%22">Lamare, F</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22de+Clermont%2C+H%22">de Clermont, H</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Burger%2C+I+A%22">Burger, I A</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Marthan%2C+R%22">Marthan, R</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22European+Radiology%22">European Radiology</searchLink>. Aug2014, Vol. 24 Issue 8, p1964-1970. 7p. – Name: Abstract Label: Abstract Group: Ab Data: <bold>Objectives: </bold>To assess variability of the average standard uptake value (SUV) computed by varying the number of hottest voxels within an (18)F-fluorodeoxyglucose ((18)F-FDG)-positive lesion. This SUV metric was compared with the maximal SUV (SUV(max): the hottest voxel) and peak SUV (SUV(peak): SUV(max) and its 26 neighbouring voxels).<bold>Methods: </bold>Twelve lung cancer patients (20 lesions) were analysed using PET dynamic acquisition involving ten successive 2.5-min frames. In each frame and lesion, average SUV obtained from the N = 5, 10, 15, 20, 25 or 30 hottest voxels (SUV(max-N)), SUV(max) and SUV(peak) were assessed. The relative standard deviations (SDrs) from ten frames were calculated for each SUV metric and lesion, yielding the mean relative SD from 20 lesions for each SUV metric (SDr(N), SDr(max) and SDr(peak)), and hence relative measurement error and repeatability (MEr-R).<bold>Results: </bold>For each N, SDr(N) was significantly lower than SDr(max) and SDr(peak). SDr(N) correlated strongly with N: 6.471 × N(-0.103) (r = 0.994; P < 0.01). MEr-R of SUV(max-30) was 8.94-12.63% (95% CL), versus 13.86-19.59% and 13.41-18.95% for SUV(max) and SUV(peak) respectively.<bold>Conclusions: </bold>Variability of SUV(max-N) is significantly lower than for SUV(max) and SUV(peak). Further prospective studies should be performed to determine the optimal total hottest volume, as voxel volume may depend on the PET system.<bold>Key Points: </bold>• PET imaging provides functional parameters of (18) F-FDG-positive lesions, such as SUVmax and SUVpeak. • Averaging SUV from several hottest voxels (SUVmax-N) is a further SUV metric. • Variability of SUVmax-N is significantly lower than SUVmax and SUVpeak variability. • SUVmax-N should improve SUV accuracy for predicting outcome or assessing treatment response. • An optimal total hottest volume should be determined through further prospective studies. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of European Radiology is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) – Name: URL Label: URL Group: URL Data: <link linkTarget="URL" linkTerm="103832326" linkWindow="_blank">103832326</link> |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s00330-014-3222-x Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 7 StartPage: 1964 Titles: – TitleFull: Variability of average SUV from several hottest voxels is lower than that of SUVmax and SUVpeak. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Laffon, E – PersonEntity: Name: NameFull: Lamare, F – PersonEntity: Name: NameFull: de Clermont, H – PersonEntity: Name: NameFull: Burger, I A – PersonEntity: Name: NameFull: Marthan, R IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 08 Text: Aug2014 Type: published Y: 2014 Identifiers: – Type: issn-print Value: 09387994 Numbering: – Type: volume Value: 24 – Type: issue Value: 8 Titles: – TitleFull: European Radiology Type: main |
| ResultId | 1 |
