Appendiceal length as an independent risk factor for acute appendicitis.

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Title: Appendiceal length as an independent risk factor for acute appendicitis.
Authors: Pickhardt, Perry J (AUTHOR), Suhonen, Joshua (AUTHOR), Lawrence, Edward M (AUTHOR), Muñoz Del Rio, Alejandro (AUTHOR), Pooler, B Dustin (AUTHOR)
Source: European Radiology. Dec2013, Vol. 23 Issue 12, p3311-3317. 7p.
Abstract: Objectives: To determine if appendiceal lengths differ between adults with acute appendicitis and asymptomatic controls.Methods: In vivo appendiceal length at computed tomography (CT) in 321 adults with surgically proven appendicitis was compared with that in 321 consecutive asymptomatic adult controls. CT length was derived using curved multiplanar reformats along the long axis. Gross pathological length provided external validation for appendectomy cases.Results: Appendiceal length at CT correlated well with appendicitis specimens (mean length, 6.8 cm vs 6.6 cm; 79 % within 1.5 cm). For asymptomatic controls, mean CT appendiceal length was 7.9 cm, longer in men (8.4 ± 3.8 vs 7.4 ± 3.1 cm; P = 0.02), matching closely historical normative post-mortem data. The mean and standard deviation of appendiceal length at CT were significantly greater among negative controls than in the positive appendicitis group (7.9 ± 3.5 vs 6.8 ± 1.9 cm; P = 0.03). Of appendicitis cases, 90 % (288/321) fell within the range 4.0-10.0 cm, compared with 59 % (189/321) of negative controls (P < 0.001). Among controls, a fivefold increase in appendixes >10 cm and a twofold increase in appendixes <4 cm were observed. Half (9/18) of long appendicitis cases showed tip appendicitis at CT.Conclusions: "Intermediate" appendiceal lengths (4-10 cm) are more frequently complicated by acute appendicitis, whereas both "long" (>10 cm) and "short" (<4 cm) lengths are more frequently observed in unaffected adults. [ABSTRACT FROM AUTHOR]
Copyright of European Radiology is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Appendiceal length as an independent risk factor for acute appendicitis.
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  Data: &lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Pickhardt%2C+Perry+J%22&quot;&gt;Pickhardt, Perry J&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Suhonen%2C+Joshua%22&quot;&gt;Suhonen, Joshua&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Lawrence%2C+Edward+M%22&quot;&gt;Lawrence, Edward M&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Mu&#241;oz+Del+Rio%2C+Alejandro%22&quot;&gt;Mu&#241;oz Del Rio, Alejandro&lt;/searchLink&gt; (AUTHOR)&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Pooler%2C+B+Dustin%22&quot;&gt;Pooler, B Dustin&lt;/searchLink&gt; (AUTHOR)
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  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22European+Radiology%22&quot;&gt;European Radiology&lt;/searchLink&gt;. Dec2013, Vol. 23 Issue 12, p3311-3317. 7p.
– Name: Abstract
  Label: Abstract
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  Data: &lt;bold&gt;Objectives: &lt;/bold&gt;To determine if appendiceal lengths differ between adults with acute appendicitis and asymptomatic controls.&lt;bold&gt;Methods: &lt;/bold&gt;In vivo appendiceal length at computed tomography (CT) in 321 adults with surgically proven appendicitis was compared with that in 321 consecutive asymptomatic adult controls. CT length was derived using curved multiplanar reformats along the long axis. Gross pathological length provided external validation for appendectomy cases.&lt;bold&gt;Results: &lt;/bold&gt;Appendiceal length at CT correlated well with appendicitis specimens (mean length, 6.8 cm vs 6.6 cm; 79 % within 1.5 cm). For asymptomatic controls, mean CT appendiceal length was 7.9 cm, longer in men (8.4 &#177; 3.8 vs 7.4 &#177; 3.1 cm; P = 0.02), matching closely historical normative post-mortem data. The mean and standard deviation of appendiceal length at CT were significantly greater among negative controls than in the positive appendicitis group (7.9 &#177; 3.5 vs 6.8 &#177; 1.9 cm; P = 0.03). Of appendicitis cases, 90 % (288/321) fell within the range 4.0-10.0 cm, compared with 59 % (189/321) of negative controls (P &lt; 0.001). Among controls, a fivefold increase in appendixes &gt;10 cm and a twofold increase in appendixes &lt;4 cm were observed. Half (9/18) of long appendicitis cases showed tip appendicitis at CT.&lt;bold&gt;Conclusions: &lt;/bold&gt;&quot;Intermediate&quot; appendiceal lengths (4-10 cm) are more frequently complicated by acute appendicitis, whereas both &quot;long&quot; (&gt;10 cm) and &quot;short&quot; (&lt;4 cm) lengths are more frequently observed in unaffected adults. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of European Radiology is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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              Text: Dec2013
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