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Characterisation of small hypoattenuating hepatic lesions in multi-detector CT (MDCT) in patients with underlying extrahepatic malignancy: added value of contrast-enhanced MR images.

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Title: Characterisation of small hypoattenuating hepatic lesions in multi-detector CT (MDCT) in patients with underlying extrahepatic malignancy: added value of contrast-enhanced MR images.
Authors: Baek SE (AUTHOR), Park MS (AUTHOR), Hong HS (AUTHOR), Choi JY (AUTHOR), Chung YE (AUTHOR), Lim JS (AUTHOR), Kim MJ (AUTHOR), Kim KW (AUTHOR), Baek, Song-Ee1 (AUTHOR), Park, Mi-Suk (AUTHOR), Hong, Hye Sook (AUTHOR), Choi, Jin Young (AUTHOR), Chung, Yong Eun (AUTHOR), Lim, Joon Seok (AUTHOR), Kim, Myeong-Jin (AUTHOR), Kim, Ki Whang (AUTHOR)
Source: European Radiology. Dec2010, Vol. 20 Issue 12, p2853-2861. 9p.
Abstract: Objective: To retrospectively assess the value of adding gadolinium-enhanced dynamic imaging to standard ununenhanced magnetic resonance imaging (MRI) for characterising hypoattenuating hepatic lesions that are too small to characterise with multi-detector computed tomography (MDCT).Methods: Informed consent was waved, and institutional review board approval was obtained. Three hundred and forty-six small (≤ 2 cm) lesions (63 metastatic, 283 benign) in 183 patients with underlying carcinoma who underwent hepatic MRI after CT were retrospectively analysed. Two radiologists independently reviewed images and diagnoses were graded on an ordinal scale from 1 (definitely benign) to 5 (definitely malignant). Receiver operating characteristic analysis was used. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy were also determined.Results: The areas under the curve of the ununenhanced images alone and with dynamic images were 0.837 and 0.850 for reader 1 (p = 0.616) and 0.771 and 0.783 for reader 2 (p = 0.700). Descriptive statistical values demonstrated sensitivities of 76% and 80%, specificities of 93% and 95%, PPVs of 69% and 79%, NPVs of 95% and 95% and accuracies of 90% and 92%, respectively.Conclusion: The value of adding three-phase contrast-enhanced MRI to unenhanced imaging did not reach statistical significance for characterising small hypoattenuating hepatic lesions on MDCT. [ABSTRACT FROM AUTHOR]
Copyright of European Radiology is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Characterisation of small hypoattenuating hepatic lesions in multi-detector CT (MDCT) in patients with underlying extrahepatic malignancy: added value of contrast-enhanced MR images.
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  Data: <searchLink fieldCode="AR" term="%22Baek+SE%22">Baek SE</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Park+MS%22">Park MS</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hong+HS%22">Hong HS</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Choi+JY%22">Choi JY</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Chung+YE%22">Chung YE</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lim+JS%22">Lim JS</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kim+MJ%22">Kim MJ</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kim+KW%22">Kim KW</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Baek%2C+Song-Ee%22">Baek, Song-Ee</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Park%2C+Mi-Suk%22">Park, Mi-Suk</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hong%2C+Hye+Sook%22">Hong, Hye Sook</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Choi%2C+Jin+Young%22">Choi, Jin Young</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Chung%2C+Yong+Eun%22">Chung, Yong Eun</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lim%2C+Joon+Seok%22">Lim, Joon Seok</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kim%2C+Myeong-Jin%22">Kim, Myeong-Jin</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kim%2C+Ki+Whang%22">Kim, Ki Whang</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22European+Radiology%22">European Radiology</searchLink>. Dec2010, Vol. 20 Issue 12, p2853-2861. 9p.
– Name: Abstract
  Label: Abstract
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  Data: <bold>Objective: </bold>To retrospectively assess the value of adding gadolinium-enhanced dynamic imaging to standard ununenhanced magnetic resonance imaging (MRI) for characterising hypoattenuating hepatic lesions that are too small to characterise with multi-detector computed tomography (MDCT).<bold>Methods: </bold>Informed consent was waved, and institutional review board approval was obtained. Three hundred and forty-six small (≤ 2 cm) lesions (63 metastatic, 283 benign) in 183 patients with underlying carcinoma who underwent hepatic MRI after CT were retrospectively analysed. Two radiologists independently reviewed images and diagnoses were graded on an ordinal scale from 1 (definitely benign) to 5 (definitely malignant). Receiver operating characteristic analysis was used. Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and accuracy were also determined.<bold>Results: </bold>The areas under the curve of the ununenhanced images alone and with dynamic images were 0.837 and 0.850 for reader 1 (p = 0.616) and 0.771 and 0.783 for reader 2 (p = 0.700). Descriptive statistical values demonstrated sensitivities of 76% and 80%, specificities of 93% and 95%, PPVs of 69% and 79%, NPVs of 95% and 95% and accuracies of 90% and 92%, respectively.<bold>Conclusion: </bold>The value of adding three-phase contrast-enhanced MRI to unenhanced imaging did not reach statistical significance for characterising small hypoattenuating hepatic lesions on MDCT. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of European Radiology is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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