View in EDS HTML Full Text PDF Full Text

T1-weighted MRI for the detection of coronary artery plaque haemorrhage.

Saved in:
Bibliographic Details
Title: T1-weighted MRI for the detection of coronary artery plaque haemorrhage.
Authors: Oei ML (AUTHOR), Ozgun M (AUTHOR), Seifarth H (AUTHOR), Bunck A (AUTHOR), Fischbach R (AUTHOR), Orwat S (AUTHOR), Heindel W (AUTHOR), Botnar R (AUTHOR), Maintz D (AUTHOR), Oei, May Lin1 (AUTHOR), Ozgun, Murat (AUTHOR), Seifarth, Harald (AUTHOR), Bunck, Alexander (AUTHOR), Fischbach, Roman (AUTHOR), Orwat, Stefan (AUTHOR), Heindel, Walter (AUTHOR), Botnar, Rene (AUTHOR), Maintz, David (AUTHOR)
Source: European Radiology. Dec2010, Vol. 20 Issue 12, p2817-2823. 7p.
Abstract: Objective: Hyperintense areas in atherosclerotic plaques on pre-contrast T1-weighted MRI have been shown to correlate with intraplaque haemorrhage. We evaluated the presence of T1 hyperintensity in coronary artery plaques in coronary artery disease (CAD) patients and correlated results with multi-detector computed tomography (MDCT) findings.Methods: Fifteen patients with CAD were included. Plaques detected by MDCT were categorised based on their Hounsfield number. T1-weighted inversion recovery (IR) MRI prepared coronary MRI for the detection of plaque and steady-state free-precession coronary MR-angiography for anatomical correlation was performed. After registration of MDCT and MRI, regions of interest were defined on MDCT-visible plaques and in corresponding vessel segments acquired with MRI. MDCT density and MR signal measurement were performed in each plaque.Results: Forty-three plaques were identified with MDCT. With IR-MRI 5/43 (12%) plaques were hyperintense, 2 of which were non-calcified and 3 mixed. Average signal-to-noise and contrast-to-noise ratios of hyperintense plaques were 15.7 and 9.1, compared with 5.6 and 1.2 for hypointense plaques. Hyperintense plaques exhibited a significantly lower CT density than hypointense plaques (63.6 vs. 140.8). There was no correlation of plaque signal intensity with degree of stenosis.Conclusion: T1-weighted IR-MRI may be useful for non-invasive detection and characterisation of intraplaque haemorrhage in coronary artery plaques. [ABSTRACT FROM AUTHOR]
Copyright of European Radiology is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: egs
DbLabel: Engineering Source
An: 104943582
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: T1-weighted MRI for the detection of coronary artery plaque haemorrhage.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Oei+ML%22">Oei ML</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ozgun+M%22">Ozgun M</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Seifarth+H%22">Seifarth H</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Bunck+A%22">Bunck A</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Fischbach+R%22">Fischbach R</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Orwat+S%22">Orwat S</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Heindel+W%22">Heindel W</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Botnar+R%22">Botnar R</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Maintz+D%22">Maintz D</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Oei%2C+May+Lin%22">Oei, May Lin</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ozgun%2C+Murat%22">Ozgun, Murat</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Seifarth%2C+Harald%22">Seifarth, Harald</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Bunck%2C+Alexander%22">Bunck, Alexander</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Fischbach%2C+Roman%22">Fischbach, Roman</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Orwat%2C+Stefan%22">Orwat, Stefan</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Heindel%2C+Walter%22">Heindel, Walter</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Botnar%2C+Rene%22">Botnar, Rene</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Maintz%2C+David%22">Maintz, David</searchLink> (AUTHOR)
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22European+Radiology%22">European Radiology</searchLink>. Dec2010, Vol. 20 Issue 12, p2817-2823. 7p.
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: <bold>Objective: </bold>Hyperintense areas in atherosclerotic plaques on pre-contrast T1-weighted MRI have been shown to correlate with intraplaque haemorrhage. We evaluated the presence of T1 hyperintensity in coronary artery plaques in coronary artery disease (CAD) patients and correlated results with multi-detector computed tomography (MDCT) findings.<bold>Methods: </bold>Fifteen patients with CAD were included. Plaques detected by MDCT were categorised based on their Hounsfield number. T1-weighted inversion recovery (IR) MRI prepared coronary MRI for the detection of plaque and steady-state free-precession coronary MR-angiography for anatomical correlation was performed. After registration of MDCT and MRI, regions of interest were defined on MDCT-visible plaques and in corresponding vessel segments acquired with MRI. MDCT density and MR signal measurement were performed in each plaque.<bold>Results: </bold>Forty-three plaques were identified with MDCT. With IR-MRI 5/43 (12%) plaques were hyperintense, 2 of which were non-calcified and 3 mixed. Average signal-to-noise and contrast-to-noise ratios of hyperintense plaques were 15.7 and 9.1, compared with 5.6 and 1.2 for hypointense plaques. Hyperintense plaques exhibited a significantly lower CT density than hypointense plaques (63.6 vs. 140.8). There was no correlation of plaque signal intensity with degree of stenosis.<bold>Conclusion: </bold>T1-weighted IR-MRI may be useful for non-invasive detection and characterisation of intraplaque haemorrhage in coronary artery plaques. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of European Radiology is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=104943582
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1007/s00330-010-1878-4
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 7
        StartPage: 2817
    Titles:
      – TitleFull: T1-weighted MRI for the detection of coronary artery plaque haemorrhage.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Oei ML
      – PersonEntity:
          Name:
            NameFull: Ozgun M
      – PersonEntity:
          Name:
            NameFull: Seifarth H
      – PersonEntity:
          Name:
            NameFull: Bunck A
      – PersonEntity:
          Name:
            NameFull: Fischbach R
      – PersonEntity:
          Name:
            NameFull: Orwat S
      – PersonEntity:
          Name:
            NameFull: Heindel W
      – PersonEntity:
          Name:
            NameFull: Botnar R
      – PersonEntity:
          Name:
            NameFull: Maintz D
      – PersonEntity:
          Name:
            NameFull: Oei, May Lin
      – PersonEntity:
          Name:
            NameFull: Ozgun, Murat
      – PersonEntity:
          Name:
            NameFull: Seifarth, Harald
      – PersonEntity:
          Name:
            NameFull: Bunck, Alexander
      – PersonEntity:
          Name:
            NameFull: Fischbach, Roman
      – PersonEntity:
          Name:
            NameFull: Orwat, Stefan
      – PersonEntity:
          Name:
            NameFull: Heindel, Walter
      – PersonEntity:
          Name:
            NameFull: Botnar, Rene
      – PersonEntity:
          Name:
            NameFull: Maintz, David
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 12
              Text: Dec2010
              Type: published
              Y: 2010
          Identifiers:
            – Type: issn-print
              Value: 09387994
          Numbering:
            – Type: volume
              Value: 20
            – Type: issue
              Value: 12
          Titles:
            – TitleFull: European Radiology
              Type: main
ResultId 1