Indicative findings of pancreatic cancer in prediagnostic CT.
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| Title: | Indicative findings of pancreatic cancer in prediagnostic CT. |
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| Authors: | Ahn SS (AUTHOR), Kim MJ (AUTHOR), Choi JY (AUTHOR), Hong HS (AUTHOR), Chung YE (AUTHOR), Lim JS (AUTHOR), Ahn, Sung Soo1 (AUTHOR), Kim, Myeong-Jin (AUTHOR), Choi, Jin-Young (AUTHOR), Hong, Hye-Suk (AUTHOR), Chung, Yong Eun (AUTHOR), Lim, Joon Seok (AUTHOR) |
| Source: | European Radiology. Oct2009, Vol. 19 Issue 10, p2448-2455. 8p. |
| Abstract: | We examined 20 prediagnostic CTs from 16 patients for whom the diagnosis of pancreatic cancer was delayed until full diagnostic CT was performed. Three radiologists independently reviewed the prediagnostic CTs along with 50 CTs of control subjects, including patients without pancreatic disease (n = 38) or with chronic pancreatitis without calcification visible on CT (n = 12). The reviewers recorded the presence of biliary or pancreatic ductal dilation, interruption of the pancreatic duct, distal parenchymal atrophy, contour abnormality and focal hypoattenuation. Frequency, sensitivity and specificity of the significant findings were calculated. Logistic regression analysis was performed. Findings indicative of pancreatic cancer were seen on 85% (17/20) of the prediagnostic CTs. Patients with pancreatic cancer were significantly (p < 0.05) more likely to show focal hypoattenuation, pancreatic duct dilation, interruption of the pancreatic duct, and distal parenchymal atrophy, with sensitivities and specificities of 75%/84%, 50%/78%, 45%/82% and 45%/96%, respectively. Focal hypoattenuation and distal parenchymal atrophy were the independent predictors of pancreatic cancer with odds ratios of 20.92 and 11.22, respectively. In conclusion, focal hypoattenuation and pancreatic duct dilation with or without interruption, especially when accompanied by distal parenchymal atrophy, were the most useful findings for avoiding delayed diagnosis of pancreatic cancer. [ABSTRACT FROM AUTHOR] |
| Copyright of European Radiology is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
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| Items | – Name: Title Label: Title Group: Ti Data: Indicative findings of pancreatic cancer in prediagnostic CT. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Ahn+SS%22">Ahn SS</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kim+MJ%22">Kim MJ</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Choi+JY%22">Choi JY</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hong+HS%22">Hong HS</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Chung+YE%22">Chung YE</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lim+JS%22">Lim JS</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ahn%2C+Sung+Soo%22">Ahn, Sung Soo</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kim%2C+Myeong-Jin%22">Kim, Myeong-Jin</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Choi%2C+Jin-Young%22">Choi, Jin-Young</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hong%2C+Hye-Suk%22">Hong, Hye-Suk</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Chung%2C+Yong+Eun%22">Chung, Yong Eun</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lim%2C+Joon+Seok%22">Lim, Joon Seok</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22European+Radiology%22">European Radiology</searchLink>. Oct2009, Vol. 19 Issue 10, p2448-2455. 8p. – Name: Abstract Label: Abstract Group: Ab Data: We examined 20 prediagnostic CTs from 16 patients for whom the diagnosis of pancreatic cancer was delayed until full diagnostic CT was performed. Three radiologists independently reviewed the prediagnostic CTs along with 50 CTs of control subjects, including patients without pancreatic disease (n = 38) or with chronic pancreatitis without calcification visible on CT (n = 12). The reviewers recorded the presence of biliary or pancreatic ductal dilation, interruption of the pancreatic duct, distal parenchymal atrophy, contour abnormality and focal hypoattenuation. Frequency, sensitivity and specificity of the significant findings were calculated. Logistic regression analysis was performed. Findings indicative of pancreatic cancer were seen on 85% (17/20) of the prediagnostic CTs. Patients with pancreatic cancer were significantly (p < 0.05) more likely to show focal hypoattenuation, pancreatic duct dilation, interruption of the pancreatic duct, and distal parenchymal atrophy, with sensitivities and specificities of 75%/84%, 50%/78%, 45%/82% and 45%/96%, respectively. Focal hypoattenuation and distal parenchymal atrophy were the independent predictors of pancreatic cancer with odds ratios of 20.92 and 11.22, respectively. In conclusion, focal hypoattenuation and pancreatic duct dilation with or without interruption, especially when accompanied by distal parenchymal atrophy, were the most useful findings for avoiding delayed diagnosis of pancreatic cancer. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of European Radiology is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s00330-009-1422-6 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 8 StartPage: 2448 Titles: – TitleFull: Indicative findings of pancreatic cancer in prediagnostic CT. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Ahn SS – PersonEntity: Name: NameFull: Kim MJ – PersonEntity: Name: NameFull: Choi JY – PersonEntity: Name: NameFull: Hong HS – PersonEntity: Name: NameFull: Chung YE – PersonEntity: Name: NameFull: Lim JS – PersonEntity: Name: NameFull: Ahn, Sung Soo – PersonEntity: Name: NameFull: Kim, Myeong-Jin – PersonEntity: Name: NameFull: Choi, Jin-Young – PersonEntity: Name: NameFull: Hong, Hye-Suk – PersonEntity: Name: NameFull: Chung, Yong Eun – PersonEntity: Name: NameFull: Lim, Joon Seok IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 10 Text: Oct2009 Type: published Y: 2009 Identifiers: – Type: issn-print Value: 09387994 Numbering: – Type: volume Value: 19 – Type: issue Value: 10 Titles: – TitleFull: European Radiology Type: main |
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