Small hypervascular hepatocellular carcinomas: value of "washout" on gadolinium-enhanced dynamic MR imaging compared to superparamagnetic iron oxide-enhanced imaging.
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| Title: | Small hypervascular hepatocellular carcinomas: value of "washout" on gadolinium-enhanced dynamic MR imaging compared to superparamagnetic iron oxide-enhanced imaging. |
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| Authors: | Yu JS (AUTHOR), Chung JJ (AUTHOR), Kim JH (AUTHOR), Kim KW (AUTHOR), Yu, Jeong-Sik1 (AUTHOR), Chung, Jae-Joon (AUTHOR), Kim, Joo Hee (AUTHOR), Kim, Ki Whang (AUTHOR) |
| Source: | European Radiology. Nov2009, Vol. 19 Issue 11, p2614-2622. 9p. |
| Abstract: | The aim of this study was to retrospectively compare the value of "washout" on dynamic MR imaging with superparamagnetic iron oxide (SPIO)-enhanced imaging features of small hepatocellular carcinoma (HCC). A total of 74 small (5-30 mm) hypervascular HCCs in 42 cirrhotic patients who underwent double contrast material-enhanced MR imaging were evaluated to determine the presence of washout in the portal or equilibrium phase of gadolinium-enhanced dynamic imaging and decreased uptake of SPIO on T2*-weighted imaging. HCCs were verified histologically (n = 13) or by serial follow-up imaging studies (n = 61). According to the size of the lesions, 27 vs. 73% (<10 mm, n = 15; P = 0.016 on McNemar test), 39 vs. 79% (10-14 mm, n = 28; P = 0.002), 50 vs. 93% (15-20 mm, n = 14; P = 0.031), and 82 vs. 100% (>20 mm, n = 17; P = 0.250) of the lesions showed washout vs. decreased SPIO accumulation respectively. The larger the lesion, the higher the prevalence of washout or decreased SPIO uptake (P = 0.004 or P = 0.036, respectively, on Mantel-Haenszel test). In many small hypervascular HCCs up to 2 cm, SPIO-enhanced MR imaging offers essential information for early diagnosis in the absence of washout on dynamic imaging. [ABSTRACT FROM AUTHOR] |
| Copyright of European Radiology is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
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| Header | DbId: egs DbLabel: Engineering Source An: 105230779 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Small hypervascular hepatocellular carcinomas: value of "washout" on gadolinium-enhanced dynamic MR imaging compared to superparamagnetic iron oxide-enhanced imaging. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Yu+JS%22">Yu JS</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Chung+JJ%22">Chung JJ</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kim+JH%22">Kim JH</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kim+KW%22">Kim KW</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Yu%2C+Jeong-Sik%22">Yu, Jeong-Sik</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Chung%2C+Jae-Joon%22">Chung, Jae-Joon</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kim%2C+Joo+Hee%22">Kim, Joo Hee</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kim%2C+Ki+Whang%22">Kim, Ki Whang</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22European+Radiology%22">European Radiology</searchLink>. Nov2009, Vol. 19 Issue 11, p2614-2622. 9p. – Name: Abstract Label: Abstract Group: Ab Data: The aim of this study was to retrospectively compare the value of "washout" on dynamic MR imaging with superparamagnetic iron oxide (SPIO)-enhanced imaging features of small hepatocellular carcinoma (HCC). A total of 74 small (5-30 mm) hypervascular HCCs in 42 cirrhotic patients who underwent double contrast material-enhanced MR imaging were evaluated to determine the presence of washout in the portal or equilibrium phase of gadolinium-enhanced dynamic imaging and decreased uptake of SPIO on T2*-weighted imaging. HCCs were verified histologically (n = 13) or by serial follow-up imaging studies (n = 61). According to the size of the lesions, 27 vs. 73% (<10 mm, n = 15; P = 0.016 on McNemar test), 39 vs. 79% (10-14 mm, n = 28; P = 0.002), 50 vs. 93% (15-20 mm, n = 14; P = 0.031), and 82 vs. 100% (>20 mm, n = 17; P = 0.250) of the lesions showed washout vs. decreased SPIO accumulation respectively. The larger the lesion, the higher the prevalence of washout or decreased SPIO uptake (P = 0.004 or P = 0.036, respectively, on Mantel-Haenszel test). In many small hypervascular HCCs up to 2 cm, SPIO-enhanced MR imaging offers essential information for early diagnosis in the absence of washout on dynamic imaging. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of European Radiology is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s00330-009-1465-8 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 9 StartPage: 2614 Titles: – TitleFull: Small hypervascular hepatocellular carcinomas: value of "washout" on gadolinium-enhanced dynamic MR imaging compared to superparamagnetic iron oxide-enhanced imaging. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Yu JS – PersonEntity: Name: NameFull: Chung JJ – PersonEntity: Name: NameFull: Kim JH – PersonEntity: Name: NameFull: Kim KW – PersonEntity: Name: NameFull: Yu, Jeong-Sik – PersonEntity: Name: NameFull: Chung, Jae-Joon – PersonEntity: Name: NameFull: Kim, Joo Hee – PersonEntity: Name: NameFull: Kim, Ki Whang IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 11 Text: Nov2009 Type: published Y: 2009 Identifiers: – Type: issn-print Value: 09387994 Numbering: – Type: volume Value: 19 – Type: issue Value: 11 Titles: – TitleFull: European Radiology Type: main |
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