Quantification of myocardial blood flow using non-ECG-triggered MR imaging.
Saved in:
| Title: | Quantification of myocardial blood flow using non-ECG-triggered MR imaging. |
|---|---|
| Authors: | Chen, David1,2, Sharif, Behzad2, Dharmakumar, Rohan2,3, Thomson, Louise E.J.4,5, Bairey Merz, C. Noel5, Berman, Daniel S.2,4, Li, Debiao2,3 |
| Source: | Magnetic Resonance in Medicine. Sep2015, Vol. 74 Issue 3, p765-771. 7p. |
| Abstract: | Purpose MR myocardial perfusion imaging is dependent on reliable electrocardiogram (ECG) triggering for accurate measurement of myocardial blood flow (MBF). A non-ECG-triggered method for quantitative first-pass imaging may improve clinical feasibility in patients with poor ECG signal. The purpose of this study is to evaluate the feasibility of a non-ECG-triggered method for myocardial perfusion imaging in a single slice. Methods The proposed non-ECG-triggered technique uses a saturation-recovery magnetization preparation and golden-angle radial acquisition for integrated arterial input function (AIF) measurement. Image based self-gating with a temporal resolution of 42.6 ms is used to generate a first-pass image series with consistent cardiac phase. The AIF is measured using beat-by-beat T1 estimation of the ventricular blood pool. The proposed technique was performed on 14 healthy volunteers and compared against a conventional ECG-triggered dual-bolus acquisition. Results The proposed method produced MBF with no significant difference compared with ECG-triggered technique (mean of 0.63 ± 0.22 mL/min/g to 0.73 ± 0.21 mL/min/g). Conclusion We have developed a non-ECG-triggered perfusion imaging method with T1 based measurement of the AIF in a single slice. In this preliminary study, our results demonstrate that MBF measured using the proposed method is comparable to the conventional ECG-triggered method. Magn Reson Med 74:765-771, 2015. © 2014 Wiley Periodicals, Inc. [ABSTRACT FROM AUTHOR] |
| Copyright of Magnetic Resonance in Medicine is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
|---|---|
| Header | DbId: egs DbLabel: Engineering Source An: 109016909 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Quantification of myocardial blood flow using non-ECG-triggered MR imaging. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Chen%2C+David%22">Chen, David</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AR" term="%22Sharif%2C+Behzad%22">Sharif, Behzad</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Dharmakumar%2C+Rohan%22">Dharmakumar, Rohan</searchLink><relatesTo>2,3</relatesTo><br /><searchLink fieldCode="AR" term="%22Thomson%2C+Louise+E%2EJ%2E%22">Thomson, Louise E.J.</searchLink><relatesTo>4,5</relatesTo><br /><searchLink fieldCode="AR" term="%22Bairey+Merz%2C+C%2E+Noel%22">Bairey Merz, C. Noel</searchLink><relatesTo>5</relatesTo><br /><searchLink fieldCode="AR" term="%22Berman%2C+Daniel+S%2E%22">Berman, Daniel S.</searchLink><relatesTo>2,4</relatesTo><br /><searchLink fieldCode="AR" term="%22Li%2C+Debiao%22">Li, Debiao</searchLink><relatesTo>2,3</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Magnetic+Resonance+in+Medicine%22">Magnetic Resonance in Medicine</searchLink>. Sep2015, Vol. 74 Issue 3, p765-771. 7p. – Name: Abstract Label: Abstract Group: Ab Data: Purpose MR myocardial perfusion imaging is dependent on reliable electrocardiogram (ECG) triggering for accurate measurement of myocardial blood flow (MBF). A non-ECG-triggered method for quantitative first-pass imaging may improve clinical feasibility in patients with poor ECG signal. The purpose of this study is to evaluate the feasibility of a non-ECG-triggered method for myocardial perfusion imaging in a single slice. Methods The proposed non-ECG-triggered technique uses a saturation-recovery magnetization preparation and golden-angle radial acquisition for integrated arterial input function (AIF) measurement. Image based self-gating with a temporal resolution of 42.6 ms is used to generate a first-pass image series with consistent cardiac phase. The AIF is measured using beat-by-beat T1 estimation of the ventricular blood pool. The proposed technique was performed on 14 healthy volunteers and compared against a conventional ECG-triggered dual-bolus acquisition. Results The proposed method produced MBF with no significant difference compared with ECG-triggered technique (mean of 0.63 ± 0.22 mL/min/g to 0.73 ± 0.21 mL/min/g). Conclusion We have developed a non-ECG-triggered perfusion imaging method with T1 based measurement of the AIF in a single slice. In this preliminary study, our results demonstrate that MBF measured using the proposed method is comparable to the conventional ECG-triggered method. Magn Reson Med 74:765-771, 2015. © 2014 Wiley Periodicals, Inc. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Magnetic Resonance in Medicine is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=109016909 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/mrm.25451 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 7 StartPage: 765 Titles: – TitleFull: Quantification of myocardial blood flow using non-ECG-triggered MR imaging. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Chen, David – PersonEntity: Name: NameFull: Sharif, Behzad – PersonEntity: Name: NameFull: Dharmakumar, Rohan – PersonEntity: Name: NameFull: Thomson, Louise E.J. – PersonEntity: Name: NameFull: Bairey Merz, C. Noel – PersonEntity: Name: NameFull: Berman, Daniel S. – PersonEntity: Name: NameFull: Li, Debiao IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 09 Text: Sep2015 Type: published Y: 2015 Identifiers: – Type: issn-print Value: 07403194 Numbering: – Type: volume Value: 74 – Type: issue Value: 3 Titles: – TitleFull: Magnetic Resonance in Medicine Type: main |
| ResultId | 1 |
