Quantification of myocardial blood flow using non-ECG-triggered MR imaging.
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| Title: | Quantification of myocardial blood flow using non-ECG-triggered MR imaging. |
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| Authors: | Chen, David1,2, Sharif, Behzad2, Dharmakumar, Rohan2,3, Thomson, Louise E.J.4,5, Bairey Merz, C. Noel5, Berman, Daniel S.2,4, Li, Debiao2,3 |
| Source: | Magnetic Resonance in Medicine. Sep2015, Vol. 74 Issue 3, p765-771. 7p. |
| Abstract: | Purpose MR myocardial perfusion imaging is dependent on reliable electrocardiogram (ECG) triggering for accurate measurement of myocardial blood flow (MBF). A non-ECG-triggered method for quantitative first-pass imaging may improve clinical feasibility in patients with poor ECG signal. The purpose of this study is to evaluate the feasibility of a non-ECG-triggered method for myocardial perfusion imaging in a single slice. Methods The proposed non-ECG-triggered technique uses a saturation-recovery magnetization preparation and golden-angle radial acquisition for integrated arterial input function (AIF) measurement. Image based self-gating with a temporal resolution of 42.6 ms is used to generate a first-pass image series with consistent cardiac phase. The AIF is measured using beat-by-beat T1 estimation of the ventricular blood pool. The proposed technique was performed on 14 healthy volunteers and compared against a conventional ECG-triggered dual-bolus acquisition. Results The proposed method produced MBF with no significant difference compared with ECG-triggered technique (mean of 0.63 ± 0.22 mL/min/g to 0.73 ± 0.21 mL/min/g). Conclusion We have developed a non-ECG-triggered perfusion imaging method with T1 based measurement of the AIF in a single slice. In this preliminary study, our results demonstrate that MBF measured using the proposed method is comparable to the conventional ECG-triggered method. Magn Reson Med 74:765-771, 2015. © 2014 Wiley Periodicals, Inc. [ABSTRACT FROM AUTHOR] |
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| Database: | Engineering Source |
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