Proteobacteria: microbial signature of dysbiosis in gut microbiota.
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| Title: | Proteobacteria: microbial signature of dysbiosis in gut microbiota. |
|---|---|
| Authors: | Shin, Na-Ri1, Whon, Tae Woong1, Bae, Jin-Woo1 baejw@khu.ac.kr |
| Source: | Trends in Biotechnology. Sep2015, Vol. 33 Issue 9, p496-503. 8p. |
| Subjects: | Inflammation, Proteobacteria, Gut microbiota, Hosts (Biology), Disease risk factors, Disease prevalence |
| Abstract: | Recent advances in sequencing techniques, applied to the study of microbial communities, have provided compelling evidence that the mammalian intestinal tract harbors a complex microbial community whose composition is a critical determinant of host health in the context of metabolism and inflammation. Given that an imbalanced gut microbiota often arises from a sustained increase in abundance of the phylum Proteobacteria , the natural human gut flora normally contains only a minor proportion of this phylum. Here, we review studies that explored the association between an abnormal expansion of Proteobacteria and a compromised ability to maintain a balanced gut microbial community. We also propose that an increased prevalence of Proteobacteria is a potential diagnostic signature of dysbiosis and risk of disease. [ABSTRACT FROM AUTHOR] |
| Copyright of Trends in Biotechnology is the property of Pergamon Press - An Imprint of Elsevier Science and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 109043263 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Proteobacteria: microbial signature of dysbiosis in gut microbiota. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Shin%2C+Na-Ri%22">Shin, Na-Ri</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Whon%2C+Tae+Woong%22">Whon, Tae Woong</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Bae%2C+Jin-Woo%22">Bae, Jin-Woo</searchLink><relatesTo>1</relatesTo><i> baejw@khu.ac.kr</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Trends+in+Biotechnology%22">Trends in Biotechnology</searchLink>. Sep2015, Vol. 33 Issue 9, p496-503. 8p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Inflammation%22">Inflammation</searchLink><br /><searchLink fieldCode="DE" term="%22Proteobacteria%22">Proteobacteria</searchLink><br /><searchLink fieldCode="DE" term="%22Gut+microbiota%22">Gut microbiota</searchLink><br /><searchLink fieldCode="DE" term="%22Hosts+%28Biology%29%22">Hosts (Biology)</searchLink><br /><searchLink fieldCode="DE" term="%22Disease+risk+factors%22">Disease risk factors</searchLink><br /><searchLink fieldCode="DE" term="%22Disease+prevalence%22">Disease prevalence</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Recent advances in sequencing techniques, applied to the study of microbial communities, have provided compelling evidence that the mammalian intestinal tract harbors a complex microbial community whose composition is a critical determinant of host health in the context of metabolism and inflammation. Given that an imbalanced gut microbiota often arises from a sustained increase in abundance of the phylum Proteobacteria , the natural human gut flora normally contains only a minor proportion of this phylum. Here, we review studies that explored the association between an abnormal expansion of Proteobacteria and a compromised ability to maintain a balanced gut microbial community. We also propose that an increased prevalence of Proteobacteria is a potential diagnostic signature of dysbiosis and risk of disease. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Trends in Biotechnology is the property of Pergamon Press - An Imprint of Elsevier Science and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.tibtech.2015.06.011 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 8 StartPage: 496 Subjects: – SubjectFull: Inflammation Type: general – SubjectFull: Proteobacteria Type: general – SubjectFull: Gut microbiota Type: general – SubjectFull: Hosts (Biology) Type: general – SubjectFull: Disease risk factors Type: general – SubjectFull: Disease prevalence Type: general Titles: – TitleFull: Proteobacteria: microbial signature of dysbiosis in gut microbiota. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Shin, Na-Ri – PersonEntity: Name: NameFull: Whon, Tae Woong – PersonEntity: Name: NameFull: Bae, Jin-Woo IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 09 Text: Sep2015 Type: published Y: 2015 Identifiers: – Type: issn-print Value: 01677799 Numbering: – Type: volume Value: 33 – Type: issue Value: 9 Titles: – TitleFull: Trends in Biotechnology Type: main |
| ResultId | 1 |
