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Distraction osteogenesis device to estimate the axial stiffness of the callus in Vivo.

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Title: Distraction osteogenesis device to estimate the axial stiffness of the callus in Vivo.
Authors: Mora-Macías, J.1 juanmora@us.es, Reina-Romo, E.1 erreina@us.es, Domínguez, J.1 jaime@us.es
Source: Medical Engineering & Physics. Oct2015, Vol. 37 Issue 10, p969-978. 10p.
Subjects: Bone growth, Callus, Bone physiology, Stiffness (Mechanics), Biomechanics, Medical equipment
Abstract: Knowing the evolution of callus stiffness is very important in distraction osteogenesis and bone healing. It allows the characterization of the bone maturation process and the assessment of the moment to retire the fixator. A new distractor device that monitors the callus axial stiffness is presented in this study. It quantifies the callus stiffness during the bone transport process with some advantages over previous methods to assess stiffness during simple distraction and bone healing. This device avoids a misalignment between bone segments, uses real load conditions, monitors forces continuously, does not involve radiation for patients, and allows the study of the complete distraction process, i.e. , the distraction and consolidation phases. The device was calibrated in vitro simulating different real bone load conditions depending on the stage of the process. The stiffness of the callus could be estimated for values between 4.2 N/mm and 9066.8 N/mm. The average relative error in measurements carried out in in vitro calibration tests was 7.8% during the distraction phase and 9.5% during the consolidation phase. These results improve the accuracy and increase the callus stiffness range of estimation with respect to other devices in the literature. In addition, the device was used successfully in vivo in a preliminary experiment. [ABSTRACT FROM AUTHOR]
Copyright of Medical Engineering & Physics is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
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  Data: Distraction osteogenesis device to estimate the axial stiffness of the callus in Vivo.
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  Data: <searchLink fieldCode="AR" term="%22Mora-Macías%2C+J%2E%22">Mora-Macías, J.</searchLink><relatesTo>1</relatesTo><i> juanmora@us.es</i><br /><searchLink fieldCode="AR" term="%22Reina-Romo%2C+E%2E%22">Reina-Romo, E.</searchLink><relatesTo>1</relatesTo><i> erreina@us.es</i><br /><searchLink fieldCode="AR" term="%22Domínguez%2C+J%2E%22">Domínguez, J.</searchLink><relatesTo>1</relatesTo><i> jaime@us.es</i>
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  Data: <searchLink fieldCode="JN" term="%22Medical+Engineering+%26+Physics%22">Medical Engineering & Physics</searchLink>. Oct2015, Vol. 37 Issue 10, p969-978. 10p.
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  Data: <searchLink fieldCode="DE" term="%22Bone+growth%22">Bone growth</searchLink><br /><searchLink fieldCode="DE" term="%22Callus%22">Callus</searchLink><br /><searchLink fieldCode="DE" term="%22Bone+physiology%22">Bone physiology</searchLink><br /><searchLink fieldCode="DE" term="%22Stiffness+%28Mechanics%29%22">Stiffness (Mechanics)</searchLink><br /><searchLink fieldCode="DE" term="%22Biomechanics%22">Biomechanics</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+equipment%22">Medical equipment</searchLink>
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  Data: Knowing the evolution of callus stiffness is very important in distraction osteogenesis and bone healing. It allows the characterization of the bone maturation process and the assessment of the moment to retire the fixator. A new distractor device that monitors the callus axial stiffness is presented in this study. It quantifies the callus stiffness during the bone transport process with some advantages over previous methods to assess stiffness during simple distraction and bone healing. This device avoids a misalignment between bone segments, uses real load conditions, monitors forces continuously, does not involve radiation for patients, and allows the study of the complete distraction process, i.e. , the distraction and consolidation phases. The device was calibrated in vitro simulating different real bone load conditions depending on the stage of the process. The stiffness of the callus could be estimated for values between 4.2 N/mm and 9066.8 N/mm. The average relative error in measurements carried out in in vitro calibration tests was 7.8% during the distraction phase and 9.5% during the consolidation phase. These results improve the accuracy and increase the callus stiffness range of estimation with respect to other devices in the literature. In addition, the device was used successfully in vivo in a preliminary experiment. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
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  Data: <i>Copyright of Medical Engineering & Physics is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1016/j.medengphy.2015.07.008
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      – Code: eng
        Text: English
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      – SubjectFull: Bone growth
        Type: general
      – SubjectFull: Callus
        Type: general
      – SubjectFull: Bone physiology
        Type: general
      – SubjectFull: Stiffness (Mechanics)
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      – SubjectFull: Biomechanics
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      – SubjectFull: Medical equipment
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      – TitleFull: Distraction osteogenesis device to estimate the axial stiffness of the callus in Vivo.
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            NameFull: Reina-Romo, E.
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              M: 10
              Text: Oct2015
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