Effects of size and surface functionalization of zinc oxide (ZnO) particles on interactions with bovine serum albumin (BSA).

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Title: Effects of size and surface functionalization of zinc oxide (ZnO) particles on interactions with bovine serum albumin (BSA).
Authors: Simonelli, G.1 gsimonelli@herrera.unt.edu.ar, Arancibia, E.L.2 earancibia@herrera.unt.edu.ar
Source: Journal of Molecular Liquids. Nov2015, Vol. 211, p742-746. 5p.
Subjects: Colloids, Serum albumin, Zinc oxide, Blood proteins, Seroconversion
Abstract: In this work, the behavior of bovine serum albumin (BSA) interacting with zinc oxide (ZnO) particles functionalized with 3-mercaptopropionic acid (3-MPA) and without any coating has been investigated. Two kinds of ZnO particles of different size and morphology were obtained: microwires (MW) and nanoparticles (NP). The effect of surface modification on the fluorescence properties of ZnO was studied. Typical ZnO green emission due to defects was not observed in the functionalized NP spectrum. Structure alterations of the protein interacting with ZnO particles were evaluated by fluorescence spectroscopy and circular dichroism (CD). Though BSA structure was not significantly perturbed in any case, some conformational changes were observed for BSA interacting with not functionalized MW. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Molecular Liquids is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Label: Title
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  Data: Effects of size and surface functionalization of zinc oxide (ZnO) particles on interactions with bovine serum albumin (BSA).
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  Data: <searchLink fieldCode="AR" term="%22Simonelli%2C+G%2E%22">Simonelli, G.</searchLink><relatesTo>1</relatesTo><i> gsimonelli@herrera.unt.edu.ar</i><br /><searchLink fieldCode="AR" term="%22Arancibia%2C+E%2EL%2E%22">Arancibia, E.L.</searchLink><relatesTo>2</relatesTo><i> earancibia@herrera.unt.edu.ar</i>
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Molecular+Liquids%22">Journal of Molecular Liquids</searchLink>. Nov2015, Vol. 211, p742-746. 5p.
– Name: Subject
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  Data: <searchLink fieldCode="DE" term="%22Colloids%22">Colloids</searchLink><br /><searchLink fieldCode="DE" term="%22Serum+albumin%22">Serum albumin</searchLink><br /><searchLink fieldCode="DE" term="%22Zinc+oxide%22">Zinc oxide</searchLink><br /><searchLink fieldCode="DE" term="%22Blood+proteins%22">Blood proteins</searchLink><br /><searchLink fieldCode="DE" term="%22Seroconversion%22">Seroconversion</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: In this work, the behavior of bovine serum albumin (BSA) interacting with zinc oxide (ZnO) particles functionalized with 3-mercaptopropionic acid (3-MPA) and without any coating has been investigated. Two kinds of ZnO particles of different size and morphology were obtained: microwires (MW) and nanoparticles (NP). The effect of surface modification on the fluorescence properties of ZnO was studied. Typical ZnO green emission due to defects was not observed in the functionalized NP spectrum. Structure alterations of the protein interacting with ZnO particles were evaluated by fluorescence spectroscopy and circular dichroism (CD). Though BSA structure was not significantly perturbed in any case, some conformational changes were observed for BSA interacting with not functionalized MW. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Journal of Molecular Liquids is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1016/j.molliq.2015.07.075
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      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 5
        StartPage: 742
    Subjects:
      – SubjectFull: Colloids
        Type: general
      – SubjectFull: Serum albumin
        Type: general
      – SubjectFull: Zinc oxide
        Type: general
      – SubjectFull: Blood proteins
        Type: general
      – SubjectFull: Seroconversion
        Type: general
    Titles:
      – TitleFull: Effects of size and surface functionalization of zinc oxide (ZnO) particles on interactions with bovine serum albumin (BSA).
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            NameFull: Simonelli, G.
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            NameFull: Arancibia, E.L.
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              M: 11
              Text: Nov2015
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              Y: 2015
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              Value: 211
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            – TitleFull: Journal of Molecular Liquids
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