Synthesis of Cyclopropyl- and Cyclobutylpiperidines: Advanced Building Blocks for Drug Discovery.

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Title: Synthesis of Cyclopropyl- and Cyclobutylpiperidines: Advanced Building Blocks for Drug Discovery.
Authors: Vyzira, Ivan I.1,2, Iminov, Rustam T.1, Tverdokhlebov, Anton1 A.tverdohlebov@mail.enamine.net, Tolmachev, Andrey A.1,3, Shcherbatiuk, Andriy V.1,3, Mykhailiuk, Pavel K.1,3 Pavel.Mykhailiuk@gmail.com, Biitseva, Angelina V.3
Source: Synthesis. 2015, Vol. 47 Issue 24, p3963-3971. 9p.
Subjects: Piperidine derivatives, Cyclopropyl compounds, Organic synthesis, Wittig reaction, Olefination reactions
Abstract: A library of cyclopropyl- and cyclobutylpiperidine derivatives were synthesized from commonly available starting materials through Wittig reactions. [ABSTRACT FROM AUTHOR]
Copyright of Synthesis is the property of Georg Thieme Verlag Stuttgart and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
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  Availability: 0
Header DbId: egs
DbLabel: Engineering Source
An: 111523513
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Data: Synthesis of Cyclopropyl- and Cyclobutylpiperidines: Advanced Building Blocks for Drug Discovery.
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  Data: <searchLink fieldCode="AR" term="%22Vyzira%2C+Ivan+I%2E%22">Vyzira, Ivan I.</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AR" term="%22Iminov%2C+Rustam+T%2E%22">Iminov, Rustam T.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Tverdokhlebov%2C+Anton%22">Tverdokhlebov, Anton</searchLink><relatesTo>1</relatesTo><i> A.tverdohlebov@mail.enamine.net</i><br /><searchLink fieldCode="AR" term="%22Tolmachev%2C+Andrey+A%2E%22">Tolmachev, Andrey A.</searchLink><relatesTo>1,3</relatesTo><br /><searchLink fieldCode="AR" term="%22Shcherbatiuk%2C+Andriy+V%2E%22">Shcherbatiuk, Andriy V.</searchLink><relatesTo>1,3</relatesTo><br /><searchLink fieldCode="AR" term="%22Mykhailiuk%2C+Pavel+K%2E%22">Mykhailiuk, Pavel K.</searchLink><relatesTo>1,3</relatesTo><i> Pavel.Mykhailiuk@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Biitseva%2C+Angelina+V%2E%22">Biitseva, Angelina V.</searchLink><relatesTo>3</relatesTo>
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  Data: <searchLink fieldCode="JN" term="%22Synthesis%22">Synthesis</searchLink>. 2015, Vol. 47 Issue 24, p3963-3971. 9p.
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  Data: <searchLink fieldCode="DE" term="%22Piperidine+derivatives%22">Piperidine derivatives</searchLink><br /><searchLink fieldCode="DE" term="%22Cyclopropyl+compounds%22">Cyclopropyl compounds</searchLink><br /><searchLink fieldCode="DE" term="%22Organic+synthesis%22">Organic synthesis</searchLink><br /><searchLink fieldCode="DE" term="%22Wittig+reaction%22">Wittig reaction</searchLink><br /><searchLink fieldCode="DE" term="%22Olefination+reactions%22">Olefination reactions</searchLink>
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  Data: A library of cyclopropyl- and cyclobutylpiperidine derivatives were synthesized from commonly available starting materials through Wittig reactions. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Synthesis is the property of Georg Thieme Verlag Stuttgart and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1055/s-0035-1560199
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      – Code: eng
        Text: English
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        PageCount: 9
        StartPage: 3963
    Subjects:
      – SubjectFull: Piperidine derivatives
        Type: general
      – SubjectFull: Cyclopropyl compounds
        Type: general
      – SubjectFull: Organic synthesis
        Type: general
      – SubjectFull: Wittig reaction
        Type: general
      – SubjectFull: Olefination reactions
        Type: general
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      – TitleFull: Synthesis of Cyclopropyl- and Cyclobutylpiperidines: Advanced Building Blocks for Drug Discovery.
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            NameFull: Tverdokhlebov, Anton
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            NameFull: Shcherbatiuk, Andriy V.
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              Text: 2015
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