Optical properties of tumor tissues grown on the chorioallantoic membrane of chicken eggs: tumor model to assay of tumor response to photodynamic therapy.
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| Title: | Optical properties of tumor tissues grown on the chorioallantoic membrane of chicken eggs: tumor model to assay of tumor response to photodynamic therapy. |
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| Authors: | Norihiro Honda1,2, Yoichiro Kariyama2, Hisanao Hazama2, Takuya Ishii3, Yuya Kitajima3, Katsushi Inoue3, Masahiro Ishizuka3, Tohru Tanaka3, Kunio Awazu2,4,5 awazu@see.eng.osaka-u.ac.jp |
| Source: | Journal of Biomedical Optics. Dec2015, Vol. 20 Issue 12, p1-8. 8p. |
| Subjects: | Imaging phantoms, Tissues -- Models, Photodynamic therapy, Phototherapy, Optical properties |
| Abstract: | Herein, the optical adequacy of a tumor model prepared with tumor cells grown on the chorioallantoic membrane (CAM) of a chicken egg is evaluated as an alternative to the mouse tumor model to assess the optimal irradiation conditions in photodynamic therapy (PDT). The optical properties of CAM and mouse tumor tissues were measured with a double integrating sphere and the inverse Monte Carlo technique in the 350- to 1000-nm wavelength range. The hemoglobin and water absorption bands observed in the CAM tumor tissue (10 eggs and 10 tumors) are equal to that of the mouse tumor tissue (8 animals and 8 tumors). The optical intersubject variability of the CAM tumor tissues meets or exceeds that of the mouse tumor tissues, and the reduced scattering coefficient spectra of CAM tumor tissues can be equated with those of mouse tumor tissues. These results confirm that the CAM tumor model is a viable alternative to the mouse tumor model, especially for deriving optimal irradiation conditions in PDT. [ABSTRACT FROM AUTHOR] |
| Copyright of Journal of Biomedical Optics is the property of SPIE - International Society of Optical Engineering and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 112239513 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Optical properties of tumor tissues grown on the chorioallantoic membrane of chicken eggs: tumor model to assay of tumor response to photodynamic therapy. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Norihiro+Honda%22">Norihiro Honda</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AR" term="%22Yoichiro+Kariyama%22">Yoichiro Kariyama</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Hisanao+Hazama%22">Hisanao Hazama</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Takuya+Ishii%22">Takuya Ishii</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Yuya+Kitajima%22">Yuya Kitajima</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Katsushi+Inoue%22">Katsushi Inoue</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Masahiro+Ishizuka%22">Masahiro Ishizuka</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Tohru+Tanaka%22">Tohru Tanaka</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Kunio+Awazu%22">Kunio Awazu</searchLink><relatesTo>2,4,5</relatesTo><i> awazu@see.eng.osaka-u.ac.jp</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Journal+of+Biomedical+Optics%22">Journal of Biomedical Optics</searchLink>. Dec2015, Vol. 20 Issue 12, p1-8. 8p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Imaging+phantoms%22">Imaging phantoms</searchLink><br /><searchLink fieldCode="DE" term="%22Tissues+--+Models%22">Tissues -- Models</searchLink><br /><searchLink fieldCode="DE" term="%22Photodynamic+therapy%22">Photodynamic therapy</searchLink><br /><searchLink fieldCode="DE" term="%22Phototherapy%22">Phototherapy</searchLink><br /><searchLink fieldCode="DE" term="%22Optical+properties%22">Optical properties</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Herein, the optical adequacy of a tumor model prepared with tumor cells grown on the chorioallantoic membrane (CAM) of a chicken egg is evaluated as an alternative to the mouse tumor model to assess the optimal irradiation conditions in photodynamic therapy (PDT). The optical properties of CAM and mouse tumor tissues were measured with a double integrating sphere and the inverse Monte Carlo technique in the 350- to 1000-nm wavelength range. The hemoglobin and water absorption bands observed in the CAM tumor tissue (10 eggs and 10 tumors) are equal to that of the mouse tumor tissue (8 animals and 8 tumors). The optical intersubject variability of the CAM tumor tissues meets or exceeds that of the mouse tumor tissues, and the reduced scattering coefficient spectra of CAM tumor tissues can be equated with those of mouse tumor tissues. These results confirm that the CAM tumor model is a viable alternative to the mouse tumor model, especially for deriving optimal irradiation conditions in PDT. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Journal of Biomedical Optics is the property of SPIE - International Society of Optical Engineering and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1117/1.JBO.20.12.125001 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 8 StartPage: 1 Subjects: – SubjectFull: Imaging phantoms Type: general – SubjectFull: Tissues -- Models Type: general – SubjectFull: Photodynamic therapy Type: general – SubjectFull: Phototherapy Type: general – SubjectFull: Optical properties Type: general Titles: – TitleFull: Optical properties of tumor tissues grown on the chorioallantoic membrane of chicken eggs: tumor model to assay of tumor response to photodynamic therapy. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Norihiro Honda – PersonEntity: Name: NameFull: Yoichiro Kariyama – PersonEntity: Name: NameFull: Hisanao Hazama – PersonEntity: Name: NameFull: Takuya Ishii – PersonEntity: Name: NameFull: Yuya Kitajima – PersonEntity: Name: NameFull: Katsushi Inoue – PersonEntity: Name: NameFull: Masahiro Ishizuka – PersonEntity: Name: NameFull: Tohru Tanaka – PersonEntity: Name: NameFull: Kunio Awazu IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 12 Text: Dec2015 Type: published Y: 2015 Identifiers: – Type: issn-print Value: 10833668 Numbering: – Type: volume Value: 20 – Type: issue Value: 12 Titles: – TitleFull: Journal of Biomedical Optics Type: main |
| ResultId | 1 |
