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Comparison of in vitro biocompatibility of a Co–Cr dental alloy produced by new milling/post-sintering or traditional casting technique.

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Title: Comparison of in vitro biocompatibility of a Co–Cr dental alloy produced by new milling/post-sintering or traditional casting technique.
Authors: Kim, Hae Ri1, Kim, Young Kyung2, Son, Jun Sik3, Min, Bong Ki4 bkmin@ynu.ac.kr, Kim, Kyo-Han5, Kwon, Tae-Yub5 tykwon@knu.ac.kr
Source: Materials Letters. Sep2016, Vol. 178, p300-303. 4p.
Subjects: Biocompatibility, In vitro studies, Dental metallurgy, Sintering, Inductively coupled plasma mass spectrometry, Metal ions
Abstract: The purpose of this study was to evaluate metal ion release of a cobalt–chromium (Co–Cr) alloy produced by using both the new milling/post-sintering (MPS) and traditional casting (CAST) techniques and the influence of ion release on cell response. The concentration of released ions from the specimens immersed in artificial saliva (pH 5.3 and 2.3) and cell culture medium was measured by inductively coupled plasma-mass spectroscopy. Cell (L929 mouse fibroblasts) response to the specimens was evaluated by water-soluble tetrazolium salt-8 assay (1, 3, and 7 days). The microstructure of the MPS specimen was characterized by fine grain size and predominant ε (hexagonal close-packed) phase. The MPS specimens showed consistently significantly smaller releases of Co ions than the CAST specimens ( P <0.05) regardless of the immersion solutions used. Although the cell morphology was normal in both groups, cell viability was consistently significantly higher in the MPS group than in the CAST group ( P <0.05). These findings suggest that the MPS-fabricated Co–Cr alloy showed better in vitro biocompatibility than the cast one. [ABSTRACT FROM AUTHOR]
Copyright of Materials Letters is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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DbLabel: Engineering Source
An: 115823515
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  Data: Comparison of in vitro biocompatibility of a Co–Cr dental alloy produced by new milling/post-sintering or traditional casting technique.
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  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22Materials+Letters%22&quot;&gt;Materials Letters&lt;/searchLink&gt;. Sep2016, Vol. 178, p300-303. 4p.
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  Data: The purpose of this study was to evaluate metal ion release of a cobalt–chromium (Co–Cr) alloy produced by using both the new milling/post-sintering (MPS) and traditional casting (CAST) techniques and the influence of ion release on cell response. The concentration of released ions from the specimens immersed in artificial saliva (pH 5.3 and 2.3) and cell culture medium was measured by inductively coupled plasma-mass spectroscopy. Cell (L929 mouse fibroblasts) response to the specimens was evaluated by water-soluble tetrazolium salt-8 assay (1, 3, and 7 days). The microstructure of the MPS specimen was characterized by fine grain size and predominant ε (hexagonal close-packed) phase. The MPS specimens showed consistently significantly smaller releases of Co ions than the CAST specimens ( P &lt;0.05) regardless of the immersion solutions used. Although the cell morphology was normal in both groups, cell viability was consistently significantly higher in the MPS group than in the CAST group ( P &lt;0.05). These findings suggest that the MPS-fabricated Co–Cr alloy showed better in vitro biocompatibility than the cast one. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of Materials Letters is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1016/j.matlet.2016.05.053
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      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 4
        StartPage: 300
    Subjects:
      – SubjectFull: Biocompatibility
        Type: general
      – SubjectFull: In vitro studies
        Type: general
      – SubjectFull: Dental metallurgy
        Type: general
      – SubjectFull: Sintering
        Type: general
      – SubjectFull: Inductively coupled plasma mass spectrometry
        Type: general
      – SubjectFull: Metal ions
        Type: general
    Titles:
      – TitleFull: Comparison of in vitro biocompatibility of a Co–Cr dental alloy produced by new milling/post-sintering or traditional casting technique.
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            NameFull: Kim, Hae Ri
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            NameFull: Kim, Young Kyung
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            NameFull: Son, Jun Sik
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            NameFull: Min, Bong Ki
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            NameFull: Kim, Kyo-Han
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            NameFull: Kwon, Tae-Yub
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            – D: 01
              M: 09
              Text: Sep2016
              Type: published
              Y: 2016
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              Value: 178
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