Free-breathing variable flip angle balanced SSFP cardiac cine imaging with reduced SAR at 3T.
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| Title: | Free-breathing variable flip angle balanced SSFP cardiac cine imaging with reduced SAR at 3T. |
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| Authors: | Srinivasan, Subashini1,2, Kroeker, Randall M.3, Gabriel, Simon1, Plotnik, Adam1, Godinez, Sergio R.1, Hu, Peng1,4, Halnon, Nancy5, Finn, J. Paul1,4, Ennis, Daniel B.1,2,4 daniel.ennis@ucla.edu |
| Source: | Magnetic Resonance in Medicine. Oct2016, Vol. 76 Issue 4, p1210-1216. 7p. |
| Abstract: | Purpose To develop a free-breathing variable flip angle (VFA) balanced steady-state free precession (bSSFP) cardiac cine imaging technique with reduced specific absorption rate (SAR) at 3 Tesla. Methods Free-breathing VFA (FB-VFA) images in the short-axis and four-chamber views were acquired using an optimal VFA scheme, then compared with conventional breath-hold constant flip angle (BH-CFA) acquisitions. Two cardiac MRI experts used a 5-point scale to score images from healthy subjects (N = 10). The left ventricular ejection fraction, end diastolic volume (LVEDV), end systolic volume, stroke volume (LVSV), and end diastolic myocardial mass (LVEDM) were determined by manual contour analysis for BH-CFA and FB-VFA. A pilot evaluation of FB-VFA was performed in one patient with Duchenne muscular dystrophy. Results FB-VFA SAR was 25% lower than BH-CFA with similar blood-myocardium contrast. The qualitative FB-VFA score was lower than the BH-CFA for the short-axis (3.1 ± 0.5 versus 4.3 ± 0.8; P < 0.05) and the four-chamber view (3.4 ± 0.4 versus 4.6 ± 0.6; P < 0.05). The LVEDV and the LVSV were 5% and 12% larger ( P < 0.05) for FB-VFA compared with BH-CFA. There was no difference in LVEDM. Conclusion FB-VFA bSSFP cardiac cine imaging decreased the SAR at 3T with image quality sufficient to perform cardiac functional analysis. Magn Reson Med 76:1210-1216, 2016. © 2015 Wiley Periodicals, Inc. [ABSTRACT FROM AUTHOR] |
| Copyright of Magnetic Resonance in Medicine is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
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| Items | – Name: Title Label: Title Group: Ti Data: Free-breathing variable flip angle balanced SSFP cardiac cine imaging with reduced SAR at 3T. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Srinivasan%2C+Subashini%22">Srinivasan, Subashini</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AR" term="%22Kroeker%2C+Randall+M%2E%22">Kroeker, Randall M.</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Gabriel%2C+Simon%22">Gabriel, Simon</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Plotnik%2C+Adam%22">Plotnik, Adam</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Godinez%2C+Sergio+R%2E%22">Godinez, Sergio R.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Hu%2C+Peng%22">Hu, Peng</searchLink><relatesTo>1,4</relatesTo><br /><searchLink fieldCode="AR" term="%22Halnon%2C+Nancy%22">Halnon, Nancy</searchLink><relatesTo>5</relatesTo><br /><searchLink fieldCode="AR" term="%22Finn%2C+J%2E+Paul%22">Finn, J. Paul</searchLink><relatesTo>1,4</relatesTo><br /><searchLink fieldCode="AR" term="%22Ennis%2C+Daniel+B%2E%22">Ennis, Daniel B.</searchLink><relatesTo>1,2,4</relatesTo><i> daniel.ennis@ucla.edu</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Magnetic+Resonance+in+Medicine%22">Magnetic Resonance in Medicine</searchLink>. Oct2016, Vol. 76 Issue 4, p1210-1216. 7p. – Name: Abstract Label: Abstract Group: Ab Data: Purpose To develop a free-breathing variable flip angle (VFA) balanced steady-state free precession (bSSFP) cardiac cine imaging technique with reduced specific absorption rate (SAR) at 3 Tesla. Methods Free-breathing VFA (FB-VFA) images in the short-axis and four-chamber views were acquired using an optimal VFA scheme, then compared with conventional breath-hold constant flip angle (BH-CFA) acquisitions. Two cardiac MRI experts used a 5-point scale to score images from healthy subjects (N = 10). The left ventricular ejection fraction, end diastolic volume (LVEDV), end systolic volume, stroke volume (LVSV), and end diastolic myocardial mass (LVEDM) were determined by manual contour analysis for BH-CFA and FB-VFA. A pilot evaluation of FB-VFA was performed in one patient with Duchenne muscular dystrophy. Results FB-VFA SAR was 25% lower than BH-CFA with similar blood-myocardium contrast. The qualitative FB-VFA score was lower than the BH-CFA for the short-axis (3.1 ± 0.5 versus 4.3 ± 0.8; P < 0.05) and the four-chamber view (3.4 ± 0.4 versus 4.6 ± 0.6; P < 0.05). The LVEDV and the LVSV were 5% and 12% larger ( P < 0.05) for FB-VFA compared with BH-CFA. There was no difference in LVEDM. Conclusion FB-VFA bSSFP cardiac cine imaging decreased the SAR at 3T with image quality sufficient to perform cardiac functional analysis. Magn Reson Med 76:1210-1216, 2016. © 2015 Wiley Periodicals, Inc. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Magnetic Resonance in Medicine is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/mrm.26011 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 7 StartPage: 1210 Titles: – TitleFull: Free-breathing variable flip angle balanced SSFP cardiac cine imaging with reduced SAR at 3T. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Srinivasan, Subashini – PersonEntity: Name: NameFull: Kroeker, Randall M. – PersonEntity: Name: NameFull: Gabriel, Simon – PersonEntity: Name: NameFull: Plotnik, Adam – PersonEntity: Name: NameFull: Godinez, Sergio R. – PersonEntity: Name: NameFull: Hu, Peng – PersonEntity: Name: NameFull: Halnon, Nancy – PersonEntity: Name: NameFull: Finn, J. Paul – PersonEntity: Name: NameFull: Ennis, Daniel B. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 10 Text: Oct2016 Type: published Y: 2016 Identifiers: – Type: issn-print Value: 07403194 Numbering: – Type: volume Value: 76 – Type: issue Value: 4 Titles: – TitleFull: Magnetic Resonance in Medicine Type: main |
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