Interactions of hypericin with a model mutagen – Acridine orange analyzed by light absorption and fluorescence spectroscopy.

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Title: Interactions of hypericin with a model mutagen – Acridine orange analyzed by light absorption and fluorescence spectroscopy.
Authors: Pietrzak, Monika1 pietrzak@uwm.edu.pl, Szabelski, Mariusz1, Kasparek, Adam1, Wieczorek, Zbigniew1
Source: Chemical Physics Letters. Feb2017, Vol. 669, p85-91. 7p.
Subjects: Hypericin, Mutagens, Acridine, Light absorption, Fluorescence spectroscopy
Abstract: The present study was designed to estimate the ability of hypericin to interact with a model mutagen – acridine orange. The hetero-association of hypericin and acridine orange was investigated with absorption and fluorescence spectroscopy methods in aqueous solution of DMSO. The data indicate that hypericin forms complexes with acridine orange and that the association constants are relatively high and depend on DMSO concentration. The absorption spectra of the hypericin – acridine orange complexes were examined as well. Owing to its ability to interact with flat aromatic compounds, hypericin may potentially be used as an interceptor molecule. [ABSTRACT FROM AUTHOR]
Copyright of Chemical Physics Letters is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Interactions of hypericin with a model mutagen – Acridine orange analyzed by light absorption and fluorescence spectroscopy.
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  Data: <searchLink fieldCode="AR" term="%22Pietrzak%2C+Monika%22">Pietrzak, Monika</searchLink><relatesTo>1</relatesTo><i> pietrzak@uwm.edu.pl</i><br /><searchLink fieldCode="AR" term="%22Szabelski%2C+Mariusz%22">Szabelski, Mariusz</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Kasparek%2C+Adam%22">Kasparek, Adam</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Wieczorek%2C+Zbigniew%22">Wieczorek, Zbigniew</searchLink><relatesTo>1</relatesTo>
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  Data: <searchLink fieldCode="JN" term="%22Chemical+Physics+Letters%22">Chemical Physics Letters</searchLink>. Feb2017, Vol. 669, p85-91. 7p.
– Name: Subject
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  Data: <searchLink fieldCode="DE" term="%22Hypericin%22">Hypericin</searchLink><br /><searchLink fieldCode="DE" term="%22Mutagens%22">Mutagens</searchLink><br /><searchLink fieldCode="DE" term="%22Acridine%22">Acridine</searchLink><br /><searchLink fieldCode="DE" term="%22Light+absorption%22">Light absorption</searchLink><br /><searchLink fieldCode="DE" term="%22Fluorescence+spectroscopy%22">Fluorescence spectroscopy</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: The present study was designed to estimate the ability of hypericin to interact with a model mutagen – acridine orange. The hetero-association of hypericin and acridine orange was investigated with absorption and fluorescence spectroscopy methods in aqueous solution of DMSO. The data indicate that hypericin forms complexes with acridine orange and that the association constants are relatively high and depend on DMSO concentration. The absorption spectra of the hypericin – acridine orange complexes were examined as well. Owing to its ability to interact with flat aromatic compounds, hypericin may potentially be used as an interceptor molecule. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
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  Data: <i>Copyright of Chemical Physics Letters is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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        Value: 10.1016/j.cplett.2016.12.040
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      – Code: eng
        Text: English
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        PageCount: 7
        StartPage: 85
    Subjects:
      – SubjectFull: Hypericin
        Type: general
      – SubjectFull: Mutagens
        Type: general
      – SubjectFull: Acridine
        Type: general
      – SubjectFull: Light absorption
        Type: general
      – SubjectFull: Fluorescence spectroscopy
        Type: general
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      – TitleFull: Interactions of hypericin with a model mutagen – Acridine orange analyzed by light absorption and fluorescence spectroscopy.
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            NameFull: Pietrzak, Monika
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            NameFull: Szabelski, Mariusz
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            NameFull: Kasparek, Adam
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              Text: Feb2017
              Type: published
              Y: 2017
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              Value: 669
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