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Comparison of physiological and post-endovascular aneurysm repair infrarenal blood flow.

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Title: Comparison of physiological and post-endovascular aneurysm repair infrarenal blood flow.
Authors: Raptis, Anastasios1, Xenos, Michalis2, Georgakarakos, Efstratios3, Kouvelos, George1, Giannoukas, Athanasios4, Labropoulos, Nicos5, Matsagkas, Miltiadis1
Source: Computer Methods in Biomechanics & Biomedical Engineering. Feb2017, Vol. 20 Issue 3, p242-249. 8p.
Subjects: Physiology, Blood flow, Computed tomography, Shearing force, Computational fluid dynamics, Pressure drop (Fluid dynamics)
Abstract: Endovascular aneurysm repair (EVAR) of abdominal aortic aneurysms results in redirection of blood through the deployed endograft (EG). Even though EVAR is clinically effective, the absolute flow restoration is not warranted. Our purpose was to compare the physiological with the post-EVAR infrarenal flow conditions. We developed patient-specific models based on computed tomography data of five healthy volunteers and ten patients treated with the Endurant®stent-graft system. Wall shear stress (WSS), helicity, pressure and velocity fields were calculated using computational fluid dynamics. The results showed a decrease of peak WSS on the part of the EG that resides in the iliac arteries, compared to the physiological value (p = 0.01). At the abdominal part, the average helicity seems to increase after EVAR, while at the iliac arteries part, the intensity of helical flow seems physiological. Pressure drop and peak velocity in the iliac arteries part are lower than the physiological values (p = 0.04). The comparison revealed that most hemodynamic properties converge to normal levels at the abdominal part whereas statistically significant variations were observed in the iliac arteries part. The delineation of the differences between physiological and postoperative flow data could pave the way for the improvement of EG designs. [ABSTRACT FROM AUTHOR]
Copyright of Computer Methods in Biomechanics & Biomedical Engineering is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
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Header DbId: egs
DbLabel: Engineering Source
An: 120793328
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Comparison of physiological and post-endovascular aneurysm repair infrarenal blood flow.
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  Data: <searchLink fieldCode="JN" term="%22Computer+Methods+in+Biomechanics+%26+Biomedical+Engineering%22">Computer Methods in Biomechanics & Biomedical Engineering</searchLink>. Feb2017, Vol. 20 Issue 3, p242-249. 8p.
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  Data: <searchLink fieldCode="DE" term="%22Physiology%22">Physiology</searchLink><br /><searchLink fieldCode="DE" term="%22Blood+flow%22">Blood flow</searchLink><br /><searchLink fieldCode="DE" term="%22Computed+tomography%22">Computed tomography</searchLink><br /><searchLink fieldCode="DE" term="%22Shearing+force%22">Shearing force</searchLink><br /><searchLink fieldCode="DE" term="%22Computational+fluid+dynamics%22">Computational fluid dynamics</searchLink><br /><searchLink fieldCode="DE" term="%22Pressure+drop+%28Fluid+dynamics%29%22">Pressure drop (Fluid dynamics)</searchLink>
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  Data: Endovascular aneurysm repair (EVAR) of abdominal aortic aneurysms results in redirection of blood through the deployed endograft (EG). Even though EVAR is clinically effective, the absolute flow restoration is not warranted. Our purpose was to compare the physiological with the post-EVAR infrarenal flow conditions. We developed patient-specific models based on computed tomography data of five healthy volunteers and ten patients treated with the Endurant®stent-graft system. Wall shear stress (WSS), helicity, pressure and velocity fields were calculated using computational fluid dynamics. The results showed a decrease of peak WSS on the part of the EG that resides in the iliac arteries, compared to the physiological value (p = 0.01). At the abdominal part, the average helicity seems to increase after EVAR, while at the iliac arteries part, the intensity of helical flow seems physiological. Pressure drop and peak velocity in the iliac arteries part are lower than the physiological values (p = 0.04). The comparison revealed that most hemodynamic properties converge to normal levels at the abdominal part whereas statistically significant variations were observed in the iliac arteries part. The delineation of the differences between physiological and postoperative flow data could pave the way for the improvement of EG designs. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Computer Methods in Biomechanics & Biomedical Engineering is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1080/10255842.2016.1215437
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      – SubjectFull: Computed tomography
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      – SubjectFull: Shearing force
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      – SubjectFull: Pressure drop (Fluid dynamics)
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      – TitleFull: Comparison of physiological and post-endovascular aneurysm repair infrarenal blood flow.
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              Text: Feb2017
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              Y: 2017
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