Low-level laser therapy as an adjunct to conventional therapy in the treatment of diabetic foot ulcers.

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Title: Low-level laser therapy as an adjunct to conventional therapy in the treatment of diabetic foot ulcers.
Authors: Mathur, R.1, Sahu, Khageswar2 khageswar@rrcat.gov.in, Saraf, Siddharth1 siddharthsaraf18@gmail.com, Patheja, Pooja2, Khan, Fareed1, Gupta, P.2, Mathur, R K3 (AUTHOR), Gupta, P K4 (AUTHOR)
Source: Lasers in Medical Science. Feb2017, Vol. 32 Issue 2, p275-282. 8p.
Subjects: Treatment of diabetic foot, Laser therapy, Tertiary care, Treatment effectiveness, Health outcome assessment, Blood sugar, Comparative studies, Demography, Research methodology, Medical cooperation, Type 2 diabetes, Research, Wound healing, Evaluation research, Diabetic foot, Randomized controlled trials, Case-control method, Physiological effects of radiation
Abstract: Foot ulcers are serious complications of diabetes mellitus (DM) and are known to be resistant to conventional treatment. This study was conducted to evaluate the efficacy of low-level laser therapy (LLLT) for the treatment of diabetic foot ulcers in a tertiary care centre (Department of Surgery, Mahatma Gandhi Memorial Medical College and Maharaja Yashwantrao Hospital, A.B. Road, Indore). A total of 30 patients with type 2 DM having Meggitt-Wagner grade I foot ulcers of more than 6 weeks duration with negative culture were studied. Patients were randomized into two groups of 15 each. Patients in study group received LLLT (660 ± 20 nm, 3 J/cm2) along with conventional therapy and those in control group were treated with conventional therapy alone. The primary outcome measure was the absolute and relative wound size reduction at 2 weeks compared to the baseline parameter. Percentage ulcer area reduction was 37 ± 9% in the LLLT group and 15 ± 5.4% in the control group (p < 0.001). For ∼75% of wounds of the treatment group, wound area reduction of 30-50% was observed. In contrast, for the control group, ∼80% of wounds showed a wound area reduction of <20% on day 15. Further, the wounds with initial wound area 1000-2000 mm2 seems to have better final outcome than the groups with larger areas. The treated groups showed higher amount of granulation than the control group. The results suggest that LLLT is beneficial as an adjunct to conventional therapy in the treatment of diabetic foot ulcers. [ABSTRACT FROM AUTHOR]
Copyright of Lasers in Medical Science is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Low-level laser therapy as an adjunct to conventional therapy in the treatment of diabetic foot ulcers.
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  Data: Foot ulcers are serious complications of diabetes mellitus (DM) and are known to be resistant to conventional treatment. This study was conducted to evaluate the efficacy of low-level laser therapy (LLLT) for the treatment of diabetic foot ulcers in a tertiary care centre (Department of Surgery, Mahatma Gandhi Memorial Medical College and Maharaja Yashwantrao Hospital, A.B. Road, Indore). A total of 30 patients with type 2 DM having Meggitt-Wagner grade I foot ulcers of more than 6&#160;weeks duration with negative culture were studied. Patients were randomized into two groups of 15 each. Patients in study group received LLLT (660 &#177; 20&#160;nm, 3&#160;J/cm2) along with conventional therapy and those in control group were treated with conventional therapy alone. The primary outcome measure was the absolute and relative wound size reduction at 2&#160;weeks compared to the baseline parameter. Percentage ulcer area reduction was 37 &#177; 9% in the LLLT group and 15 &#177; 5.4% in the control group (p &lt; 0.001). For ∼75% of wounds of the treatment group, wound area reduction of 30-50% was observed. In contrast, for the control group, ∼80% of wounds showed a wound area reduction of &lt;20% on day 15. Further, the wounds with initial wound area 1000-2000&#160;mm2 seems to have better final outcome than the groups with larger areas. The treated groups showed higher amount of granulation than the control group. The results suggest that LLLT is beneficial as an adjunct to conventional therapy in the treatment of diabetic foot ulcers. [ABSTRACT FROM AUTHOR]
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  Data: &lt;i&gt;Copyright of Lasers in Medical Science is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
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        Value: 10.1007/s10103-016-2109-2
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      – SubjectFull: Treatment of diabetic foot
        Type: general
      – SubjectFull: Laser therapy
        Type: general
      – SubjectFull: Tertiary care
        Type: general
      – SubjectFull: Treatment effectiveness
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      – SubjectFull: Blood sugar
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      – SubjectFull: Type 2 diabetes
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      – SubjectFull: Wound healing
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      – SubjectFull: Diabetic foot
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