Low-level laser therapy as an adjunct to conventional therapy in the treatment of diabetic foot ulcers.
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| Title: | Low-level laser therapy as an adjunct to conventional therapy in the treatment of diabetic foot ulcers. |
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| Authors: | Mathur, R.1, Sahu, Khageswar2 khageswar@rrcat.gov.in, Saraf, Siddharth1 siddharthsaraf18@gmail.com, Patheja, Pooja2, Khan, Fareed1, Gupta, P.2, Mathur, R K3 (AUTHOR), Gupta, P K4 (AUTHOR) |
| Source: | Lasers in Medical Science. Feb2017, Vol. 32 Issue 2, p275-282. 8p. |
| Subjects: | Treatment of diabetic foot, Laser therapy, Tertiary care, Treatment effectiveness, Health outcome assessment, Blood sugar, Comparative studies, Demography, Research methodology, Medical cooperation, Type 2 diabetes, Research, Wound healing, Evaluation research, Diabetic foot, Randomized controlled trials, Case-control method, Physiological effects of radiation |
| Abstract: | Foot ulcers are serious complications of diabetes mellitus (DM) and are known to be resistant to conventional treatment. This study was conducted to evaluate the efficacy of low-level laser therapy (LLLT) for the treatment of diabetic foot ulcers in a tertiary care centre (Department of Surgery, Mahatma Gandhi Memorial Medical College and Maharaja Yashwantrao Hospital, A.B. Road, Indore). A total of 30 patients with type 2 DM having Meggitt-Wagner grade I foot ulcers of more than 6 weeks duration with negative culture were studied. Patients were randomized into two groups of 15 each. Patients in study group received LLLT (660 ± 20 nm, 3 J/cm2) along with conventional therapy and those in control group were treated with conventional therapy alone. The primary outcome measure was the absolute and relative wound size reduction at 2 weeks compared to the baseline parameter. Percentage ulcer area reduction was 37 ± 9% in the LLLT group and 15 ± 5.4% in the control group (p < 0.001). For ∼75% of wounds of the treatment group, wound area reduction of 30-50% was observed. In contrast, for the control group, ∼80% of wounds showed a wound area reduction of <20% on day 15. Further, the wounds with initial wound area 1000-2000 mm2 seems to have better final outcome than the groups with larger areas. The treated groups showed higher amount of granulation than the control group. The results suggest that LLLT is beneficial as an adjunct to conventional therapy in the treatment of diabetic foot ulcers. [ABSTRACT FROM AUTHOR] |
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| Database: | Engineering Source |
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| Items | – Name: Title Label: Title Group: Ti Data: Low-level laser therapy as an adjunct to conventional therapy in the treatment of diabetic foot ulcers. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Mathur%2C+R%2E%22">Mathur, R.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Sahu%2C+Khageswar%22">Sahu, Khageswar</searchLink><relatesTo>2</relatesTo><i> khageswar@rrcat.gov.in</i><br /><searchLink fieldCode="AR" term="%22Saraf%2C+Siddharth%22">Saraf, Siddharth</searchLink><relatesTo>1</relatesTo><i> siddharthsaraf18@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Patheja%2C+Pooja%22">Patheja, Pooja</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Khan%2C+Fareed%22">Khan, Fareed</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Gupta%2C+P%2E%22">Gupta, P.</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Mathur%2C+R+K%22">Mathur, R K</searchLink><relatesTo>3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Gupta%2C+P+K%22">Gupta, P K</searchLink><relatesTo>4</relatesTo> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Lasers+in+Medical+Science%22">Lasers in Medical Science</searchLink>. Feb2017, Vol. 32 Issue 2, p275-282. 8p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Treatment+of+diabetic+foot%22">Treatment of diabetic foot</searchLink><br /><searchLink fieldCode="DE" term="%22Laser+therapy%22">Laser therapy</searchLink><br /><searchLink fieldCode="DE" term="%22Tertiary+care%22">Tertiary care</searchLink><br /><searchLink fieldCode="DE" term="%22Treatment+effectiveness%22">Treatment effectiveness</searchLink><br /><searchLink fieldCode="DE" term="%22Health+outcome+assessment%22">Health outcome assessment</searchLink><br /><searchLink fieldCode="DE" term="%22Blood+sugar%22">Blood sugar</searchLink><br /><searchLink fieldCode="DE" term="%22Comparative+studies%22">Comparative studies</searchLink><br /><searchLink fieldCode="DE" term="%22Demography%22">Demography</searchLink><br /><searchLink fieldCode="DE" term="%22Research+methodology%22">Research methodology</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+cooperation%22">Medical cooperation</searchLink><br /><searchLink fieldCode="DE" term="%22Type+2+diabetes%22">Type 2 diabetes</searchLink><br /><searchLink fieldCode="DE" term="%22Research%22">Research</searchLink><br /><searchLink fieldCode="DE" term="%22Wound+healing%22">Wound healing</searchLink><br /><searchLink fieldCode="DE" term="%22Evaluation+research%22">Evaluation research</searchLink><br /><searchLink fieldCode="DE" term="%22Diabetic+foot%22">Diabetic foot</searchLink><br /><searchLink fieldCode="DE" term="%22Randomized+controlled+trials%22">Randomized controlled trials</searchLink><br /><searchLink fieldCode="DE" term="%22Case-control+method%22">Case-control method</searchLink><br /><searchLink fieldCode="DE" term="%22Physiological+effects+of+radiation%22">Physiological effects of radiation</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Foot ulcers are serious complications of diabetes mellitus (DM) and are known to be resistant to conventional treatment. This study was conducted to evaluate the efficacy of low-level laser therapy (LLLT) for the treatment of diabetic foot ulcers in a tertiary care centre (Department of Surgery, Mahatma Gandhi Memorial Medical College and Maharaja Yashwantrao Hospital, A.B. Road, Indore). A total of 30 patients with type 2 DM having Meggitt-Wagner grade I foot ulcers of more than 6 weeks duration with negative culture were studied. Patients were randomized into two groups of 15 each. Patients in study group received LLLT (660 ± 20 nm, 3 J/cm2) along with conventional therapy and those in control group were treated with conventional therapy alone. The primary outcome measure was the absolute and relative wound size reduction at 2 weeks compared to the baseline parameter. Percentage ulcer area reduction was 37 ± 9% in the LLLT group and 15 ± 5.4% in the control group (p < 0.001). For ∼75% of wounds of the treatment group, wound area reduction of 30-50% was observed. In contrast, for the control group, ∼80% of wounds showed a wound area reduction of <20% on day 15. Further, the wounds with initial wound area 1000-2000 mm2 seems to have better final outcome than the groups with larger areas. The treated groups showed higher amount of granulation than the control group. The results suggest that LLLT is beneficial as an adjunct to conventional therapy in the treatment of diabetic foot ulcers. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Lasers in Medical Science is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s10103-016-2109-2 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 8 StartPage: 275 Subjects: – SubjectFull: Treatment of diabetic foot Type: general – SubjectFull: Laser therapy Type: general – SubjectFull: Tertiary care Type: general – SubjectFull: Treatment effectiveness Type: general – SubjectFull: Health outcome assessment Type: general – SubjectFull: Blood sugar Type: general – SubjectFull: Comparative studies Type: general – SubjectFull: Demography Type: general – SubjectFull: Research methodology Type: general – SubjectFull: Medical cooperation Type: general – SubjectFull: Type 2 diabetes Type: general – SubjectFull: Research Type: general – SubjectFull: Wound healing Type: general – SubjectFull: Evaluation research Type: general – SubjectFull: Diabetic foot Type: general – SubjectFull: Randomized controlled trials Type: general – SubjectFull: Case-control method Type: general – SubjectFull: Physiological effects of radiation Type: general Titles: – TitleFull: Low-level laser therapy as an adjunct to conventional therapy in the treatment of diabetic foot ulcers. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Mathur, R. – PersonEntity: Name: NameFull: Sahu, Khageswar – PersonEntity: Name: NameFull: Saraf, Siddharth – PersonEntity: Name: NameFull: Patheja, Pooja – PersonEntity: Name: NameFull: Khan, Fareed – PersonEntity: Name: NameFull: Gupta, P. – PersonEntity: Name: NameFull: Mathur, R K – PersonEntity: Name: NameFull: Gupta, P K IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 02 Text: Feb2017 Type: published Y: 2017 Identifiers: – Type: issn-print Value: 02688921 Numbering: – Type: volume Value: 32 – Type: issue Value: 2 Titles: – TitleFull: Lasers in Medical Science Type: main |
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