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Design considerations for electroporation reactors.

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Title: Design considerations for electroporation reactors.
Authors: Sack, Martin1, Mueller, Georg1
Source: IEEE Transactions on Dielectrics & Electrical Insulation. Aug2017, Vol. 24 Issue 4, p1992-2000. 9p.
Subjects: Electroporation, Electric fields, Energy consumption, Electrodes, Sugar beets
Abstract: An electroporation reactor comprises a treatment area for the application of pulsed electric fields to biological tissue. A homogeneous opening of cells within the whole treatment area can be achieved by applying a homogeneously distributed electric field of sufficient field strength and also sufficient total energy to the tissue. However, such an ideal homogeneous electric field can be achieved in a closed volume only. Inlet and outlet of an electroporation reactor designed for a continuous flow of material involve inhomogeneities of the electric field. Such inhomogeneities cause additional losses due to current flowing also in low-field regions, which are ineffective for electroporation. Depending on the design of the electrode system also the electric field in the center of the electroporation area might be to some extend inhomogeneous. So the specific energy required for the treatment of a defined volume of material depends on the electrode design. When comparing this specific energy to the specific energy required in the ideal case of a treatment area with a homogeneous field, a factor describing the energy efficiency of the electrode design can be defined. The paper describes this approach in more detail. [ABSTRACT FROM AUTHOR]
Copyright of IEEE Transactions on Dielectrics & Electrical Insulation is the property of IEEE and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
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DbLabel: Engineering Source
An: 125207081
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Data: Design considerations for electroporation reactors.
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  Data: <searchLink fieldCode="DE" term="%22Electroporation%22">Electroporation</searchLink><br /><searchLink fieldCode="DE" term="%22Electric+fields%22">Electric fields</searchLink><br /><searchLink fieldCode="DE" term="%22Energy+consumption%22">Energy consumption</searchLink><br /><searchLink fieldCode="DE" term="%22Electrodes%22">Electrodes</searchLink><br /><searchLink fieldCode="DE" term="%22Sugar+beets%22">Sugar beets</searchLink>
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  Data: An electroporation reactor comprises a treatment area for the application of pulsed electric fields to biological tissue. A homogeneous opening of cells within the whole treatment area can be achieved by applying a homogeneously distributed electric field of sufficient field strength and also sufficient total energy to the tissue. However, such an ideal homogeneous electric field can be achieved in a closed volume only. Inlet and outlet of an electroporation reactor designed for a continuous flow of material involve inhomogeneities of the electric field. Such inhomogeneities cause additional losses due to current flowing also in low-field regions, which are ineffective for electroporation. Depending on the design of the electrode system also the electric field in the center of the electroporation area might be to some extend inhomogeneous. So the specific energy required for the treatment of a defined volume of material depends on the electrode design. When comparing this specific energy to the specific energy required in the ideal case of a treatment area with a homogeneous field, a factor describing the energy efficiency of the electrode design can be defined. The paper describes this approach in more detail. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
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  Data: <i>Copyright of IEEE Transactions on Dielectrics & Electrical Insulation is the property of IEEE and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1109/TDEI.2016.006219
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      – Code: eng
        Text: English
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      Pagination:
        PageCount: 9
        StartPage: 1992
    Subjects:
      – SubjectFull: Electroporation
        Type: general
      – SubjectFull: Electric fields
        Type: general
      – SubjectFull: Energy consumption
        Type: general
      – SubjectFull: Electrodes
        Type: general
      – SubjectFull: Sugar beets
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      – TitleFull: Design considerations for electroporation reactors.
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              Text: Aug2017
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