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Metabolic engineering strategies for acetoin and 2,3-butanediol production: advances and prospects.

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Title: Metabolic engineering strategies for acetoin and 2,3-butanediol production: advances and prospects.
Authors: Yang, Taowei1,2 (AUTHOR), Rao, Zhiming1,2 (AUTHOR) raozhm@jiangnan.edu.cn, Zhang, Xian1 (AUTHOR), Xu, Meijuan1 (AUTHOR), Xu, Zhenghong3 (AUTHOR), Yang, Shang-Tian4 (AUTHOR)
Source: Critical Reviews in Biotechnology. Dec2017, Vol. 37 Issue 8, p990-1005. 16p.
Subjects: Acetoin, Butanediol manufacturing, Systems biology, Synthetic biology, Bacterial metabolites
Abstract: Acetoin and 2,3-butanediol (2,3-BD) have a large number of industrial applications. The production of acetoin and 2,3-BD has traditionally relied on oil supplies. Microbial production of acetoin and 2,3-BD will alleviate the dependence on oil. Acetoin and 2,3-BD are neighboring metabolites in the 2,3-BD metabolic pathway of bacteria. This review summarizes metabolic engineering strategies for improvement of microbial acetoin and 2,3-BD production. We also propose enhancements to current acetoin and 2,3-BD production strategies, by offering a metabolic engineering approach that is guided by systems biology and synthetic biology. [ABSTRACT FROM PUBLISHER]
Copyright of Critical Reviews in Biotechnology is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
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  Label: Title
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  Data: Metabolic engineering strategies for acetoin and 2,3-butanediol production: advances and prospects.
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  Data: <searchLink fieldCode="AR" term="%22Yang%2C+Taowei%22">Yang, Taowei</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Rao%2C+Zhiming%22">Rao, Zhiming</searchLink><relatesTo>1,2</relatesTo> (AUTHOR)<i> raozhm@jiangnan.edu.cn</i><br /><searchLink fieldCode="AR" term="%22Zhang%2C+Xian%22">Zhang, Xian</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Xu%2C+Meijuan%22">Xu, Meijuan</searchLink><relatesTo>1</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Xu%2C+Zhenghong%22">Xu, Zhenghong</searchLink><relatesTo>3</relatesTo> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Yang%2C+Shang-Tian%22">Yang, Shang-Tian</searchLink><relatesTo>4</relatesTo> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Critical+Reviews+in+Biotechnology%22">Critical Reviews in Biotechnology</searchLink>. Dec2017, Vol. 37 Issue 8, p990-1005. 16p.
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  Data: <searchLink fieldCode="DE" term="%22Acetoin%22">Acetoin</searchLink><br /><searchLink fieldCode="DE" term="%22Butanediol+manufacturing%22">Butanediol manufacturing</searchLink><br /><searchLink fieldCode="DE" term="%22Systems+biology%22">Systems biology</searchLink><br /><searchLink fieldCode="DE" term="%22Synthetic+biology%22">Synthetic biology</searchLink><br /><searchLink fieldCode="DE" term="%22Bacterial+metabolites%22">Bacterial metabolites</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Acetoin and 2,3-butanediol (2,3-BD) have a large number of industrial applications. The production of acetoin and 2,3-BD has traditionally relied on oil supplies. Microbial production of acetoin and 2,3-BD will alleviate the dependence on oil. Acetoin and 2,3-BD are neighboring metabolites in the 2,3-BD metabolic pathway of bacteria. This review summarizes metabolic engineering strategies for improvement of microbial acetoin and 2,3-BD production. We also propose enhancements to current acetoin and 2,3-BD production strategies, by offering a metabolic engineering approach that is guided by systems biology and synthetic biology. [ABSTRACT FROM PUBLISHER]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Critical Reviews in Biotechnology is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=125207446
RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1080/07388551.2017.1299680
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      – Code: eng
        Text: English
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        PageCount: 16
        StartPage: 990
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        Type: general
      – SubjectFull: Butanediol manufacturing
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      – SubjectFull: Systems biology
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      – SubjectFull: Synthetic biology
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      – SubjectFull: Bacterial metabolites
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            NameFull: Xu, Zhenghong
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              Text: Dec2017
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