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Non-labeled selective virus detection with novel SERS-active porous silver nanofilms fabricated by Electron Beam Physical Vapor Deposition.

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Title: Non-labeled selective virus detection with novel SERS-active porous silver nanofilms fabricated by Electron Beam Physical Vapor Deposition.
Authors: Durmanov, Nikolay N.1 durmanstein@gmail.com, Guliev, Rustam R.1, Eremenko, Arkady V.1, Boginskaya, Irina A.2, Ryzhikov, Ilya A.2,3, Trifonova, Ekaterina A.4, Putlyaev, Egor V.4, Mukhin, Aleksei N.5, Kalnov, Sergey L.5, Balandina, Marina V.5, Tkachuk, Artem P.5, Gushchin, Vladimir A.5, Sarychev, Andrey K.2, Lagarkov, Andrey N.2, Rodionov, Ilya A.3,6, Gabidullin, Aidar R.3,6, Kurochkin, Ilya N.1,4
Source: Sensors & Actuators B: Chemical. Mar2018, Vol. 257, p37-47. 11p.
Subjects: Physical vapor deposition, Electron beams, Electron beam lithography, Electron cyclotron resonance sources, Fabrication (Manufacturing)
Abstract: Virus detection is often performed using antibody-based and polymerase chain reaction-based techniques. Such methods have major deficiencies, caused by time-consuming and labor-intensive incubation and purification steps. In this contribution, a novel SERS substrate for qualitative virus detection was developed and described. The substrate is composed of a thin silver film with folded surface structure containing pore-like nanoscale cavities and indentations, deposited on mica substrate by electron beam physical vapor deposition method. Pore-like structures are semi-regularly arrayed, with a rough surface in between, allowing for SERS activity, and their size and periodicity can be manipulated in the manufacturing process. It was speculated that viral particles could be trapped in these structures and would generate easily detectable enhanced Raman signals. The SERS substrate was tested against detection of four virus species – rabbit myxomatosis virus, canine distemper virus, tobacco mosaic virus and potato virus X. Specific spectra were obtained and analyzed for each virus. Data analysis demonstrated successful differentiation between tested species. The reported results demonstrate that novel SERS substrate is suitable for detection and identification of viral particles. [ABSTRACT FROM AUTHOR]
Copyright of Sensors & Actuators B: Chemical is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
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Header DbId: egs
DbLabel: Engineering Source
An: 126993894
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PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Data: Non-labeled selective virus detection with novel SERS-active porous silver nanofilms fabricated by Electron Beam Physical Vapor Deposition.
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  Data: <searchLink fieldCode="AR" term="%22Durmanov%2C+Nikolay+N%2E%22">Durmanov, Nikolay N.</searchLink><relatesTo>1</relatesTo><i> durmanstein@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Guliev%2C+Rustam+R%2E%22">Guliev, Rustam R.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Eremenko%2C+Arkady+V%2E%22">Eremenko, Arkady V.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Boginskaya%2C+Irina+A%2E%22">Boginskaya, Irina A.</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Ryzhikov%2C+Ilya+A%2E%22">Ryzhikov, Ilya A.</searchLink><relatesTo>2,3</relatesTo><br /><searchLink fieldCode="AR" term="%22Trifonova%2C+Ekaterina+A%2E%22">Trifonova, Ekaterina A.</searchLink><relatesTo>4</relatesTo><br /><searchLink fieldCode="AR" term="%22Putlyaev%2C+Egor+V%2E%22">Putlyaev, Egor V.</searchLink><relatesTo>4</relatesTo><br /><searchLink fieldCode="AR" term="%22Mukhin%2C+Aleksei+N%2E%22">Mukhin, Aleksei N.</searchLink><relatesTo>5</relatesTo><br /><searchLink fieldCode="AR" term="%22Kalnov%2C+Sergey+L%2E%22">Kalnov, Sergey L.</searchLink><relatesTo>5</relatesTo><br /><searchLink fieldCode="AR" term="%22Balandina%2C+Marina+V%2E%22">Balandina, Marina V.</searchLink><relatesTo>5</relatesTo><br /><searchLink fieldCode="AR" term="%22Tkachuk%2C+Artem+P%2E%22">Tkachuk, Artem P.</searchLink><relatesTo>5</relatesTo><br /><searchLink fieldCode="AR" term="%22Gushchin%2C+Vladimir+A%2E%22">Gushchin, Vladimir A.</searchLink><relatesTo>5</relatesTo><br /><searchLink fieldCode="AR" term="%22Sarychev%2C+Andrey+K%2E%22">Sarychev, Andrey K.</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Lagarkov%2C+Andrey+N%2E%22">Lagarkov, Andrey N.</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Rodionov%2C+Ilya+A%2E%22">Rodionov, Ilya A.</searchLink><relatesTo>3,6</relatesTo><br /><searchLink fieldCode="AR" term="%22Gabidullin%2C+Aidar+R%2E%22">Gabidullin, Aidar R.</searchLink><relatesTo>3,6</relatesTo><br /><searchLink fieldCode="AR" term="%22Kurochkin%2C+Ilya+N%2E%22">Kurochkin, Ilya N.</searchLink><relatesTo>1,4</relatesTo>
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  Data: <searchLink fieldCode="JN" term="%22Sensors+%26+Actuators+B%3A+Chemical%22">Sensors & Actuators B: Chemical</searchLink>. Mar2018, Vol. 257, p37-47. 11p.
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  Data: <searchLink fieldCode="DE" term="%22Physical+vapor+deposition%22">Physical vapor deposition</searchLink><br /><searchLink fieldCode="DE" term="%22Electron+beams%22">Electron beams</searchLink><br /><searchLink fieldCode="DE" term="%22Electron+beam+lithography%22">Electron beam lithography</searchLink><br /><searchLink fieldCode="DE" term="%22Electron+cyclotron+resonance+sources%22">Electron cyclotron resonance sources</searchLink><br /><searchLink fieldCode="DE" term="%22Fabrication+%28Manufacturing%29%22">Fabrication (Manufacturing)</searchLink>
– Name: Abstract
  Label: Abstract
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  Data: Virus detection is often performed using antibody-based and polymerase chain reaction-based techniques. Such methods have major deficiencies, caused by time-consuming and labor-intensive incubation and purification steps. In this contribution, a novel SERS substrate for qualitative virus detection was developed and described. The substrate is composed of a thin silver film with folded surface structure containing pore-like nanoscale cavities and indentations, deposited on mica substrate by electron beam physical vapor deposition method. Pore-like structures are semi-regularly arrayed, with a rough surface in between, allowing for SERS activity, and their size and periodicity can be manipulated in the manufacturing process. It was speculated that viral particles could be trapped in these structures and would generate easily detectable enhanced Raman signals. The SERS substrate was tested against detection of four virus species – rabbit myxomatosis virus, canine distemper virus, tobacco mosaic virus and potato virus X. Specific spectra were obtained and analyzed for each virus. Data analysis demonstrated successful differentiation between tested species. The reported results demonstrate that novel SERS substrate is suitable for detection and identification of viral particles. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Sensors & Actuators B: Chemical is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1016/j.snb.2017.10.022
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      – SubjectFull: Electron beam lithography
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      – SubjectFull: Electron cyclotron resonance sources
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