Hand drawn paper-based optical assay plate for rapid and trace level determination of Ag+ in water.

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Title: Hand drawn paper-based optical assay plate for rapid and trace level determination of Ag+ in water.
Authors: Dhavamani, Jeyakumar1, Mujawar, Liyakat Hamid1 liyakat.mujawar@gmail.com, El-Shahawi, Mohammad Soror2,3
Source: Sensors & Actuators B: Chemical. Apr2018, Vol. 258, p321-330. 10p.
Subjects: Patterning therapy, Hydrophobic surfaces, Methyl methacrylate, Chromogenic compounds, Quantitative research
Abstract: Patterning of hydrophobic barriers is duly important for designing paper-based analytical devices. Hydrophobic ink composing of solubilized poly(methyl methacrylate) was re-filled into the commercially available correction pen that was used to draw microzones/hydrophobic barriers on filter paper surface. The stability of hydrophobic barriers was strong enough to withstand elevated surrounding temperatures. The hand-drawn optical assay plate (OAP) was subsequently used for rapid and precise determination of Ag + ions using 6-hydroxy-3-(2-oxoindolin-3-ylideneamino)-2-thioxo-2H-1,3-thiazin-4(3H)-one (HOTT) as a chromogenic reagent. Within the microzones, the developed reddish brown colored Ag-HOTT chelate was easily visualized by naked eyes at trace level (10 −1 μM) of Ag + in water. The assay sensitivity on the proposed platform was 3-orders of magnitude lower to the similar assay executed on pristine filter paper. Quantitative analysis of Ag-HOTT complex by image analysis software showed a linear dynamic range between (10 1 –10 4 μM) with a regression coefficient (R 2 ) of 0.995. The proposed Ag + assay offers easy colorimetric read-out and flexibility in point-of-use testing. The versatility of the in-house fabricated OAP can be easily extended towards other analytes as well especially in resource limited areas. [ABSTRACT FROM AUTHOR]
Copyright of Sensors & Actuators B: Chemical is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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DbLabel: Engineering Source
An: 127385135
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  Data: Hand drawn paper-based optical assay plate for rapid and trace level determination of Ag+ in water.
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  Data: <searchLink fieldCode="AR" term="%22Dhavamani%2C+Jeyakumar%22">Dhavamani, Jeyakumar</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Mujawar%2C+Liyakat+Hamid%22">Mujawar, Liyakat Hamid</searchLink><relatesTo>1</relatesTo><i> liyakat.mujawar@gmail.com</i><br /><searchLink fieldCode="AR" term="%22El-Shahawi%2C+Mohammad+Soror%22">El-Shahawi, Mohammad Soror</searchLink><relatesTo>2,3</relatesTo>
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  Data: <searchLink fieldCode="JN" term="%22Sensors+%26+Actuators+B%3A+Chemical%22">Sensors & Actuators B: Chemical</searchLink>. Apr2018, Vol. 258, p321-330. 10p.
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  Data: <searchLink fieldCode="DE" term="%22Patterning+therapy%22">Patterning therapy</searchLink><br /><searchLink fieldCode="DE" term="%22Hydrophobic+surfaces%22">Hydrophobic surfaces</searchLink><br /><searchLink fieldCode="DE" term="%22Methyl+methacrylate%22">Methyl methacrylate</searchLink><br /><searchLink fieldCode="DE" term="%22Chromogenic+compounds%22">Chromogenic compounds</searchLink><br /><searchLink fieldCode="DE" term="%22Quantitative+research%22">Quantitative research</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Patterning of hydrophobic barriers is duly important for designing paper-based analytical devices. Hydrophobic ink composing of solubilized poly(methyl methacrylate) was re-filled into the commercially available correction pen that was used to draw microzones/hydrophobic barriers on filter paper surface. The stability of hydrophobic barriers was strong enough to withstand elevated surrounding temperatures. The hand-drawn optical assay plate (OAP) was subsequently used for rapid and precise determination of Ag + ions using 6-hydroxy-3-(2-oxoindolin-3-ylideneamino)-2-thioxo-2H-1,3-thiazin-4(3H)-one (HOTT) as a chromogenic reagent. Within the microzones, the developed reddish brown colored Ag-HOTT chelate was easily visualized by naked eyes at trace level (10 −1 μM) of Ag + in water. The assay sensitivity on the proposed platform was 3-orders of magnitude lower to the similar assay executed on pristine filter paper. Quantitative analysis of Ag-HOTT complex by image analysis software showed a linear dynamic range between (10 1 –10 4 μM) with a regression coefficient (R 2 ) of 0.995. The proposed Ag + assay offers easy colorimetric read-out and flexibility in point-of-use testing. The versatility of the in-house fabricated OAP can be easily extended towards other analytes as well especially in resource limited areas. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Sensors & Actuators B: Chemical is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1016/j.snb.2017.11.111
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      – Code: eng
        Text: English
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        PageCount: 10
        StartPage: 321
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      – SubjectFull: Patterning therapy
        Type: general
      – SubjectFull: Hydrophobic surfaces
        Type: general
      – SubjectFull: Methyl methacrylate
        Type: general
      – SubjectFull: Chromogenic compounds
        Type: general
      – SubjectFull: Quantitative research
        Type: general
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      – TitleFull: Hand drawn paper-based optical assay plate for rapid and trace level determination of Ag+ in water.
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            NameFull: Dhavamani, Jeyakumar
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            NameFull: Mujawar, Liyakat Hamid
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            NameFull: El-Shahawi, Mohammad Soror
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            – D: 01
              M: 04
              Text: Apr2018
              Type: published
              Y: 2018
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              Value: 258
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