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Development and characterization of a point-of care rate-based transcutaneous respiratory status monitor.

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Title: Development and characterization of a point-of care rate-based transcutaneous respiratory status monitor.
Authors: Ge, Xudong1 xge1@umbc.edu, Adangwa, Prosper1, Lim, Ja Young1, Kostov, Yordan1, Tolosa, Leah1, Pierson, Richard2, Herr, Daniel2, Rao, Govind1 grao@umbc.edu
Source: Medical Engineering & Physics. Jun2018, Vol. 56, p36-41. 6p.
Subjects: Transcutaneous electrical nerve stimulation, Respiratory agents, Mass transfer, Transcutaneous blood gas monitoring, Gas detectors
Abstract: Blood gas measurements provide vital clinical information in critical care. The current “gold standard” for blood gas measurements involves obtaining blood samples, which can be painful and can lead to bleeding, thrombus formation, or infection. Mass transfer equilibrium-based transcutaneous blood gas monitors have been used since the 1970s, but they require heating the skin to ≥42   °C to speed up the transcutaneous gas diffusion. Thus, these devices have a potential risk for skin burns. Here we report a new generation of noninvasive device for respiratory status assessment. Instead of waiting for mass transfer equilibrium, the blood gas levels are monitored by measuring the transcutaneous diffusion rate, which is proportional to blood gas concentration. The startup time of this device is almost independent of skin temperature, so the measurement can be made at any body temperature. The test results show that this device can track the blood gas levels quickly even at normal body temperature. [ABSTRACT FROM AUTHOR]
Copyright of Medical Engineering & Physics is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
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DbLabel: Engineering Source
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PubType: Academic Journal
PubTypeId: academicJournal
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  Data: Development and characterization of a point-of care rate-based transcutaneous respiratory status monitor.
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  Data: <searchLink fieldCode="AR" term="%22Ge%2C+Xudong%22">Ge, Xudong</searchLink><relatesTo>1</relatesTo><i> xge1@umbc.edu</i><br /><searchLink fieldCode="AR" term="%22Adangwa%2C+Prosper%22">Adangwa, Prosper</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Lim%2C+Ja+Young%22">Lim, Ja Young</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Kostov%2C+Yordan%22">Kostov, Yordan</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Tolosa%2C+Leah%22">Tolosa, Leah</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Pierson%2C+Richard%22">Pierson, Richard</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Herr%2C+Daniel%22">Herr, Daniel</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Rao%2C+Govind%22">Rao, Govind</searchLink><relatesTo>1</relatesTo><i> grao@umbc.edu</i>
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  Data: <searchLink fieldCode="JN" term="%22Medical+Engineering+%26+Physics%22">Medical Engineering & Physics</searchLink>. Jun2018, Vol. 56, p36-41. 6p.
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  Data: <searchLink fieldCode="DE" term="%22Transcutaneous+electrical+nerve+stimulation%22">Transcutaneous electrical nerve stimulation</searchLink><br /><searchLink fieldCode="DE" term="%22Respiratory+agents%22">Respiratory agents</searchLink><br /><searchLink fieldCode="DE" term="%22Mass+transfer%22">Mass transfer</searchLink><br /><searchLink fieldCode="DE" term="%22Transcutaneous+blood+gas+monitoring%22">Transcutaneous blood gas monitoring</searchLink><br /><searchLink fieldCode="DE" term="%22Gas+detectors%22">Gas detectors</searchLink>
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  Data: Blood gas measurements provide vital clinical information in critical care. The current “gold standard” for blood gas measurements involves obtaining blood samples, which can be painful and can lead to bleeding, thrombus formation, or infection. Mass transfer equilibrium-based transcutaneous blood gas monitors have been used since the 1970s, but they require heating the skin to ≥42   °C to speed up the transcutaneous gas diffusion. Thus, these devices have a potential risk for skin burns. Here we report a new generation of noninvasive device for respiratory status assessment. Instead of waiting for mass transfer equilibrium, the blood gas levels are monitored by measuring the transcutaneous diffusion rate, which is proportional to blood gas concentration. The startup time of this device is almost independent of skin temperature, so the measurement can be made at any body temperature. The test results show that this device can track the blood gas levels quickly even at normal body temperature. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Medical Engineering & Physics is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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      – Type: doi
        Value: 10.1016/j.medengphy.2018.03.009
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      – Code: eng
        Text: English
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        Type: general
      – SubjectFull: Respiratory agents
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      – SubjectFull: Mass transfer
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      – SubjectFull: Transcutaneous blood gas monitoring
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      – SubjectFull: Gas detectors
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              Text: Jun2018
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              Y: 2018
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