View in EDS

One-Lung Flooding Enables Ultrasound-Guided Transthoracic Needle Biopsy of Pulmonary Nodules with High Sensitivity.

Saved in:
Bibliographic Details
Title: One-Lung Flooding Enables Ultrasound-Guided Transthoracic Needle Biopsy of Pulmonary Nodules with High Sensitivity.
Authors: Lesser, Thomas Günter1 Thomas.Lesser@srh.de, Petersen, Iver2, Pölzing, Frank3, Wolfram, Frank1
Source: Ultrasound in Medicine & Biology. Jul2018, Vol. 44 Issue 7, p1556-1562. 7p.
Subjects: Ultrasonic imaging, Needle biopsy, Pulmonary nodules, Lung tumors, Chest X rays, Animal experimentation, Biopsy, Comparative studies, Lungs, Research methodology, Medical cooperation, Research, Swine, Evaluation research
Abstract: Ultrasound-guided transthoracic needle biopsy (USgTTNB) can only be used for peripheral tumours that contact the pleura. Sonographic accessibility of the entire lung can be achieved using one-lung flooding. In this study, feasibility, sensitivity and complication rate of USgTTNB of lung nodules after one-lung flooding in an ex vivo and in vivo lung tumour model were assessed. USgTTNB was performed ex vivo after one-lung flooding in 10 resected human lung lobes containing carcinoma or metastasis. USgTTNB after one-lung flooding and simulation of a lung nodule was conducted in vivo in 5 animals. Transthoracic sonography and chest X-ray were obtained 30 min after reventilation. The lungs were examined macroscopically and histopathologically. The pathologic diagnosis was confirmed in 85.7% and 100% of tumours after first and second puncture attempts, respectively. The successful puncture rate in vivo was 90%. Neither pneumothorax nor bleeding was observed. One-lung flooding enables USgTTNB of lung nodules with a high sensitivity and minimal risk of complications in a pre-clinical model. [ABSTRACT FROM AUTHOR]
Copyright of Ultrasound in Medicine & Biology is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
FullText Text:
  Availability: 0
Header DbId: egs
DbLabel: Engineering Source
An: 129647769
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: One-Lung Flooding Enables Ultrasound-Guided Transthoracic Needle Biopsy of Pulmonary Nodules with High Sensitivity.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Lesser%2C+Thomas+Günter%22">Lesser, Thomas Günter</searchLink><relatesTo>1</relatesTo><i> Thomas.Lesser@srh.de</i><br /><searchLink fieldCode="AR" term="%22Petersen%2C+Iver%22">Petersen, Iver</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Pölzing%2C+Frank%22">Pölzing, Frank</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Wolfram%2C+Frank%22">Wolfram, Frank</searchLink><relatesTo>1</relatesTo>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Ultrasound+in+Medicine+%26+Biology%22">Ultrasound in Medicine & Biology</searchLink>. Jul2018, Vol. 44 Issue 7, p1556-1562. 7p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Ultrasonic+imaging%22">Ultrasonic imaging</searchLink><br /><searchLink fieldCode="DE" term="%22Needle+biopsy%22">Needle biopsy</searchLink><br /><searchLink fieldCode="DE" term="%22Pulmonary+nodules%22">Pulmonary nodules</searchLink><br /><searchLink fieldCode="DE" term="%22Lung+tumors%22">Lung tumors</searchLink><br /><searchLink fieldCode="DE" term="%22Chest+X+rays%22">Chest X rays</searchLink><br /><searchLink fieldCode="DE" term="%22Animal+experimentation%22">Animal experimentation</searchLink><br /><searchLink fieldCode="DE" term="%22Biopsy%22">Biopsy</searchLink><br /><searchLink fieldCode="DE" term="%22Comparative+studies%22">Comparative studies</searchLink><br /><searchLink fieldCode="DE" term="%22Lungs%22">Lungs</searchLink><br /><searchLink fieldCode="DE" term="%22Research+methodology%22">Research methodology</searchLink><br /><searchLink fieldCode="DE" term="%22Medical+cooperation%22">Medical cooperation</searchLink><br /><searchLink fieldCode="DE" term="%22Research%22">Research</searchLink><br /><searchLink fieldCode="DE" term="%22Swine%22">Swine</searchLink><br /><searchLink fieldCode="DE" term="%22Evaluation+research%22">Evaluation research</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Ultrasound-guided transthoracic needle biopsy (USgTTNB) can only be used for peripheral tumours that contact the pleura. Sonographic accessibility of the entire lung can be achieved using one-lung flooding. In this study, feasibility, sensitivity and complication rate of USgTTNB of lung nodules after one-lung flooding in an ex vivo and in vivo lung tumour model were assessed. USgTTNB was performed ex vivo after one-lung flooding in 10 resected human lung lobes containing carcinoma or metastasis. USgTTNB after one-lung flooding and simulation of a lung nodule was conducted in vivo in 5 animals. Transthoracic sonography and chest X-ray were obtained 30 min after reventilation. The lungs were examined macroscopically and histopathologically. The pathologic diagnosis was confirmed in 85.7% and 100% of tumours after first and second puncture attempts, respectively. The successful puncture rate in vivo was 90%. Neither pneumothorax nor bleeding was observed. One-lung flooding enables USgTTNB of lung nodules with a high sensitivity and minimal risk of complications in a pre-clinical model. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Ultrasound in Medicine & Biology is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=129647769
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1016/j.ultrasmedbio.2018.03.003
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 7
        StartPage: 1556
    Subjects:
      – SubjectFull: Ultrasonic imaging
        Type: general
      – SubjectFull: Needle biopsy
        Type: general
      – SubjectFull: Pulmonary nodules
        Type: general
      – SubjectFull: Lung tumors
        Type: general
      – SubjectFull: Chest X rays
        Type: general
      – SubjectFull: Animal experimentation
        Type: general
      – SubjectFull: Biopsy
        Type: general
      – SubjectFull: Comparative studies
        Type: general
      – SubjectFull: Lungs
        Type: general
      – SubjectFull: Research methodology
        Type: general
      – SubjectFull: Medical cooperation
        Type: general
      – SubjectFull: Research
        Type: general
      – SubjectFull: Swine
        Type: general
      – SubjectFull: Evaluation research
        Type: general
    Titles:
      – TitleFull: One-Lung Flooding Enables Ultrasound-Guided Transthoracic Needle Biopsy of Pulmonary Nodules with High Sensitivity.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Lesser, Thomas Günter
      – PersonEntity:
          Name:
            NameFull: Petersen, Iver
      – PersonEntity:
          Name:
            NameFull: Pölzing, Frank
      – PersonEntity:
          Name:
            NameFull: Wolfram, Frank
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 07
              Text: Jul2018
              Type: published
              Y: 2018
          Identifiers:
            – Type: issn-print
              Value: 03015629
          Numbering:
            – Type: volume
              Value: 44
            – Type: issue
              Value: 7
          Titles:
            – TitleFull: Ultrasound in Medicine & Biology
              Type: main
ResultId 1