“Metal-free” synthesis of 1,2,3-triazoles via tandem azidation, intramolecular [3+2]-cycloaddition and aromatization of ethyl acrylate derivatives.
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| Title: | “Metal-free” synthesis of 1,2,3-triazoles via tandem azidation, intramolecular [3+2]-cycloaddition and aromatization of ethyl acrylate derivatives. |
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| Authors: | Kumar, B. Senthil1, Gadakh, Sunita1, Sudalai, Arumugam1 a.sudalai@ncl.res.in |
| Source: | Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Jun2018, Vol. 59 Issue 24, p2365-2367. 3p. |
| Subjects: | Triazoles synthesis, Azidation, Ring formation (Chemistry), Aromatization, Ethyl acrylate, Chemical derivatives |
| Abstract: | An efficient “one-pot” method for the synthesis of substituted 1,2,3-triazole derivatives in excellent yields as single regioisomer is reported. The key transformation involves an atom-efficient tandem azidation, intramolecular [3+2]-cycloaddition and aromatization of acrylate derivatives on treatment with NaN 3 in DMF under mild conditions. [ABSTRACT FROM AUTHOR] |
| Copyright of Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry is the property of Pergamon Press - An Imprint of Elsevier Science and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 129680427 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.tetlet.2018.05.020 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 3 StartPage: 2365 Subjects: – SubjectFull: Triazoles synthesis Type: general – SubjectFull: Azidation Type: general – SubjectFull: Ring formation (Chemistry) Type: general – SubjectFull: Aromatization Type: general – SubjectFull: Ethyl acrylate Type: general – SubjectFull: Chemical derivatives Type: general Titles: – TitleFull: “Metal-free” synthesis of 1,2,3-triazoles via tandem azidation, intramolecular [3+2]-cycloaddition and aromatization of ethyl acrylate derivatives. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Kumar, B. Senthil – PersonEntity: Name: NameFull: Gadakh, Sunita – PersonEntity: Name: NameFull: Sudalai, Arumugam IsPartOfRelationships: – BibEntity: Dates: – D: 13 M: 06 Text: Jun2018 Type: published Y: 2018 Identifiers: – Type: issn-print Value: 00404039 Numbering: – Type: volume Value: 59 – Type: issue Value: 24 Titles: – TitleFull: Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry Type: main |
| ResultId | 1 |
