Cross‐vendor harmonization of T2‐relaxation‐under‐spin‐tagging (TRUST) MRI for the assessment of cerebral venous oxygenation.
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| Title: | Cross‐vendor harmonization of T |
|---|---|
| Authors: | Jiang, Dengrong1, Liu, Peiying2, Li, Yang2,3, Mao, Deng2,3, Xu, Cuimei2, Lu, Hanzhang1,2,4 hanzhang.lu@jhu.edu |
| Source: | Magnetic Resonance in Medicine. Sep2018, Vol. 80 Issue 3, p1125-1131. 7p. |
| Abstract: | Purpose: Cerebral venous oxygenation (Yv) is an important physiological parameter and has potential clinical application in many brain diseases. T2‐relaxation‐under‐spin‐tagging (TRUST) is a commonly used MRI method to measure Yv. Harmonization of this technique across MRI vendors is important for dissemination and multicenter studies of brain oxygenation and metabolism as a disease biomarker. Methods: TRUST pulse sequence components and imaging parameters were carefully matched between two major MRI vendors, Philips and Siemens. Each subject (N = 10) was scanned on both scanners within a 2.5‐h period. On each scanner, the subject was scanned in two sessions to assess intersession reproducibility. A hyperoxia challenge was also included in both sessions and on both scanners to evaluate the sensitivity of the technique to Yv changes. Measured Yv values, confidence interval of Yv estimates ( ε Y v), as well as intrasession and intersession coefficient of variation (CoV) of Yv, were compared between the two scanners. Results: Yv measured on the two vendors were highly compatible and strongly correlated (R2 = 0.957). Yv changes associated with hyperoxia challenge were significant on both scanners (P < 0.001) and were also correlated across scanners (P = 0.007). Intrasession and intersession CoV of measured Yv were less than 3% and showed no difference between scanners. ε Y v were less than 1% on both scanners and showed no difference between scanners when echo times were matched on the two scanners. Conclusion: This work suggests that harmonized TRUST MRI can yield highly compatible Yv measurements across different vendors. Magn Reson Med 80:1125–1131, 2018. © 2018 International Society for Magnetic Resonance in Medicine. [ABSTRACT FROM AUTHOR] |
| Copyright of Magnetic Resonance in Medicine is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
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| Items | – Name: Title Label: Title Group: Ti Data: Cross‐vendor harmonization of T<subscript>2</subscript>‐relaxation‐under‐spin‐tagging (TRUST) MRI for the assessment of cerebral venous oxygenation. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Jiang%2C+Dengrong%22">Jiang, Dengrong</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Liu%2C+Peiying%22">Liu, Peiying</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Li%2C+Yang%22">Li, Yang</searchLink><relatesTo>2,3</relatesTo><br /><searchLink fieldCode="AR" term="%22Mao%2C+Deng%22">Mao, Deng</searchLink><relatesTo>2,3</relatesTo><br /><searchLink fieldCode="AR" term="%22Xu%2C+Cuimei%22">Xu, Cuimei</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Lu%2C+Hanzhang%22">Lu, Hanzhang</searchLink><relatesTo>1,2,4</relatesTo><i> hanzhang.lu@jhu.edu</i> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Magnetic+Resonance+in+Medicine%22">Magnetic Resonance in Medicine</searchLink>. Sep2018, Vol. 80 Issue 3, p1125-1131. 7p. – Name: Abstract Label: Abstract Group: Ab Data: Purpose: Cerebral venous oxygenation (Yv) is an important physiological parameter and has potential clinical application in many brain diseases. T2‐relaxation‐under‐spin‐tagging (TRUST) is a commonly used MRI method to measure Yv. Harmonization of this technique across MRI vendors is important for dissemination and multicenter studies of brain oxygenation and metabolism as a disease biomarker. Methods: TRUST pulse sequence components and imaging parameters were carefully matched between two major MRI vendors, Philips and Siemens. Each subject (N = 10) was scanned on both scanners within a 2.5‐h period. On each scanner, the subject was scanned in two sessions to assess intersession reproducibility. A hyperoxia challenge was also included in both sessions and on both scanners to evaluate the sensitivity of the technique to Yv changes. Measured Yv values, confidence interval of Yv estimates ( ε Y v), as well as intrasession and intersession coefficient of variation (CoV) of Yv, were compared between the two scanners. Results: Yv measured on the two vendors were highly compatible and strongly correlated (R2 = 0.957). Yv changes associated with hyperoxia challenge were significant on both scanners (P < 0.001) and were also correlated across scanners (P = 0.007). Intrasession and intersession CoV of measured Yv were less than 3% and showed no difference between scanners. ε Y v were less than 1% on both scanners and showed no difference between scanners when echo times were matched on the two scanners. Conclusion: This work suggests that harmonized TRUST MRI can yield highly compatible Yv measurements across different vendors. Magn Reson Med 80:1125–1131, 2018. © 2018 International Society for Magnetic Resonance in Medicine. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Magnetic Resonance in Medicine is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/mrm.27080 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 7 StartPage: 1125 Titles: – TitleFull: Cross‐vendor harmonization of T2‐relaxation‐under‐spin‐tagging (TRUST) MRI for the assessment of cerebral venous oxygenation. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Jiang, Dengrong – PersonEntity: Name: NameFull: Liu, Peiying – PersonEntity: Name: NameFull: Li, Yang – PersonEntity: Name: NameFull: Mao, Deng – PersonEntity: Name: NameFull: Xu, Cuimei – PersonEntity: Name: NameFull: Lu, Hanzhang IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 09 Text: Sep2018 Type: published Y: 2018 Identifiers: – Type: issn-print Value: 07403194 Numbering: – Type: volume Value: 80 – Type: issue Value: 3 Titles: – TitleFull: Magnetic Resonance in Medicine Type: main |
| ResultId | 1 |
