In silico dynamic characterization of the femur: Physiological versus mechanical boundary conditions.

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Title: In silico dynamic characterization of the femur: Physiological versus mechanical boundary conditions.
Authors: Reina-Romo, E.1, Rodríguez-Vallés, J.1, Sanz-Herrera, J.A.1 jsanz@us.es
Source: Medical Engineering & Physics. Aug2018, Vol. 58, p80-85. 6p.
Subjects: Femur physiology, Bone mechanics, Surface analysis, Modal analysis, Finite element method
Abstract: It is established that bone tissue adapts and responds to mechanical loading. Several studies have suggested an existence of positive influence of vibration on the bone mass maintenance. Thus, some bone regeneration therapies are based on vibration of bone tissue under circumstances of disease to stimulate its formation. Frequency of loading should be properly selected and therefore a correct characterization of the dynamic properties of this tissue may be critical for the success of such orthopedic techniques. On the other hand, many studies implement vibration techniques with in silico models. Numerical results are exclusively dependent on properties of bone tissue, i.e. geometry, density distribution and stiffness, as well as boundary conditions. In the present study, the influence of boundary conditions and material properties on the dynamic characteristics of bone tissue was explored in a human femur. Bone shape and density were directly reconstructed from computer tomographies, whereas natural frequencies and modes of vibration were obtained for different boundary conditions including physiological and mechanical ones. Results of this study show the moderate effect of material properties compared to the much substantial effect of boundary conditions. A factor of 2 in the natural frequency was obtained depending on imposed boundary conditions, highlighting the importance in the selection of appropriate conditions in the analysis of the bone organ. [ABSTRACT FROM AUTHOR]
Copyright of Medical Engineering & Physics is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: In silico dynamic characterization of the femur: Physiological versus mechanical boundary conditions.
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  Data: <searchLink fieldCode="AR" term="%22Reina-Romo%2C+E%2E%22">Reina-Romo, E.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Rodríguez-Vallés%2C+J%2E%22">Rodríguez-Vallés, J.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Sanz-Herrera%2C+J%2EA%2E%22">Sanz-Herrera, J.A.</searchLink><relatesTo>1</relatesTo><i> jsanz@us.es</i>
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  Data: <searchLink fieldCode="JN" term="%22Medical+Engineering+%26+Physics%22">Medical Engineering & Physics</searchLink>. Aug2018, Vol. 58, p80-85. 6p.
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  Data: <searchLink fieldCode="DE" term="%22Femur+physiology%22">Femur physiology</searchLink><br /><searchLink fieldCode="DE" term="%22Bone+mechanics%22">Bone mechanics</searchLink><br /><searchLink fieldCode="DE" term="%22Surface+analysis%22">Surface analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Modal+analysis%22">Modal analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Finite+element+method%22">Finite element method</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: It is established that bone tissue adapts and responds to mechanical loading. Several studies have suggested an existence of positive influence of vibration on the bone mass maintenance. Thus, some bone regeneration therapies are based on vibration of bone tissue under circumstances of disease to stimulate its formation. Frequency of loading should be properly selected and therefore a correct characterization of the dynamic properties of this tissue may be critical for the success of such orthopedic techniques. On the other hand, many studies implement vibration techniques with in silico models. Numerical results are exclusively dependent on properties of bone tissue, i.e. geometry, density distribution and stiffness, as well as boundary conditions. In the present study, the influence of boundary conditions and material properties on the dynamic characteristics of bone tissue was explored in a human femur. Bone shape and density were directly reconstructed from computer tomographies, whereas natural frequencies and modes of vibration were obtained for different boundary conditions including physiological and mechanical ones. Results of this study show the moderate effect of material properties compared to the much substantial effect of boundary conditions. A factor of 2 in the natural frequency was obtained depending on imposed boundary conditions, highlighting the importance in the selection of appropriate conditions in the analysis of the bone organ. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Medical Engineering & Physics is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.1016/j.medengphy.2018.06.001
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      – Code: eng
        Text: English
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      Pagination:
        PageCount: 6
        StartPage: 80
    Subjects:
      – SubjectFull: Femur physiology
        Type: general
      – SubjectFull: Bone mechanics
        Type: general
      – SubjectFull: Surface analysis
        Type: general
      – SubjectFull: Modal analysis
        Type: general
      – SubjectFull: Finite element method
        Type: general
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      – TitleFull: In silico dynamic characterization of the femur: Physiological versus mechanical boundary conditions.
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            NameFull: Reina-Romo, E.
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            NameFull: Rodríguez-Vallés, J.
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            NameFull: Sanz-Herrera, J.A.
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            – D: 01
              M: 08
              Text: Aug2018
              Type: published
              Y: 2018
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              Value: 58
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