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A new cause of false positive voriconazole levels: Watch your collection tubes!

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Title: A new cause of false positive voriconazole levels: Watch your collection tubes!
Authors: Burillo, Almudena1,2,3 almudena.burillo@gmail.com, Gómez-López, Alicia4 aliciagl@isciii.es, Escribano, Pilar2, Galar, Alicia2, Salinas, Beatriz2,5 bsalinas@hggm.es, Díaz-Pérez, Nadire1,2, Muñoz, Patricia1,2,3,6 pmunoz@micro.hggm.es, Bouza, Emilio1,2,3,6
Source: Journal of Chromatography B: Analytical Technologies in the Biomedical & Life Sciences. Aug2018, Vol. 1092, p328-331. 4p.
Subjects: Voriconazole, High performance liquid chromatography, Blood testing, Ultraviolet radiation, Diagnostic errors
Abstract: We communicate the interference of a compound of the blood collection tube with the accuracy of a validated high-pressure liquid chromatography method with ultraviolet detection for quantifying voriconazole levels, which led to false positive results. This could have serious consequences for patient management. Our advice is to implement external assessment programs. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Chromatography B: Analytical Technologies in the Biomedical & Life Sciences is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
FullText Text:
  Availability: 0
Header DbId: egs
DbLabel: Engineering Source
An: 130601423
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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  Label: Title
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  Data: A new cause of false positive voriconazole levels: Watch your collection tubes!
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  Data: <searchLink fieldCode="AR" term="%22Burillo%2C+Almudena%22">Burillo, Almudena</searchLink><relatesTo>1,2,3</relatesTo><i> almudena.burillo@gmail.com</i><br /><searchLink fieldCode="AR" term="%22Gómez-López%2C+Alicia%22">Gómez-López, Alicia</searchLink><relatesTo>4</relatesTo><i> aliciagl@isciii.es</i><br /><searchLink fieldCode="AR" term="%22Escribano%2C+Pilar%22">Escribano, Pilar</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Galar%2C+Alicia%22">Galar, Alicia</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Salinas%2C+Beatriz%22">Salinas, Beatriz</searchLink><relatesTo>2,5</relatesTo><i> bsalinas@hggm.es</i><br /><searchLink fieldCode="AR" term="%22Díaz-Pérez%2C+Nadire%22">Díaz-Pérez, Nadire</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AR" term="%22Muñoz%2C+Patricia%22">Muñoz, Patricia</searchLink><relatesTo>1,2,3,6</relatesTo><i> pmunoz@micro.hggm.es</i><br /><searchLink fieldCode="AR" term="%22Bouza%2C+Emilio%22">Bouza, Emilio</searchLink><relatesTo>1,2,3,6</relatesTo>
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Chromatography+B%3A+Analytical+Technologies+in+the+Biomedical+%26+Life+Sciences%22">Journal of Chromatography B: Analytical Technologies in the Biomedical & Life Sciences</searchLink>. Aug2018, Vol. 1092, p328-331. 4p.
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  Data: <searchLink fieldCode="DE" term="%22Voriconazole%22">Voriconazole</searchLink><br /><searchLink fieldCode="DE" term="%22High+performance+liquid+chromatography%22">High performance liquid chromatography</searchLink><br /><searchLink fieldCode="DE" term="%22Blood+testing%22">Blood testing</searchLink><br /><searchLink fieldCode="DE" term="%22Ultraviolet+radiation%22">Ultraviolet radiation</searchLink><br /><searchLink fieldCode="DE" term="%22Diagnostic+errors%22">Diagnostic errors</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: We communicate the interference of a compound of the blood collection tube with the accuracy of a validated high-pressure liquid chromatography method with ultraviolet detection for quantifying voriconazole levels, which led to false positive results. This could have serious consequences for patient management. Our advice is to implement external assessment programs. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Journal of Chromatography B: Analytical Technologies in the Biomedical & Life Sciences is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=130601423
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        Value: 10.1016/j.jchromb.2018.06.022
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      – Code: eng
        Text: English
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        StartPage: 328
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      – SubjectFull: Voriconazole
        Type: general
      – SubjectFull: High performance liquid chromatography
        Type: general
      – SubjectFull: Blood testing
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      – SubjectFull: Ultraviolet radiation
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      – SubjectFull: Diagnostic errors
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              Text: Aug2018
              Type: published
              Y: 2018
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