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Non-enhanced Pattern on Contrast-Enhanced Ultrasound in the Local Efficacy Assessment of Irreversible Electroporation Ablation of Pancreatic Adenocarcinoma.

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Title: Non-enhanced Pattern on Contrast-Enhanced Ultrasound in the Local Efficacy Assessment of Irreversible Electroporation Ablation of Pancreatic Adenocarcinoma.
Authors: Lin, Manxia1, Xie, Xiaoyan1, Xu, Ming1, Feng, Shiting2, Tian, Wenshuo1, Zhuang, Bowen1, Su, Liya1, Ye, Jieyi1, Lin, Jinhua1, Liang, Ping3, Yu, Jie3, Kuang, Ming1,4 kuangm@mail.sysu.edu.cn
Source: Ultrasound in Medicine & Biology. Sep2018, Vol. 44 Issue 9, p1986-1995. 10p.
Subjects: Ultrasonic imaging, Electroporation, Adenocarcinoma, Pancreatic cancer diagnosis, Diagnosis, Patients
Abstract: The objective was to evaluate the diagnostic value of contrast-enhanced ultrasound in the assessment of the local efficacy after irreversible electroporation (IRE) ablation of pancreatic adenocarcinoma 1 mo after ablation. Fifteen patients with pancreatic adenocarcinoma were treated with IRE and then examined by contrast-enhanced ultrasound 1 mo after ablation. The contrast agent was SonoVue. Technical efficacy was assessed at 3 mo after IRE and classified as technical efficiency (TE) and technical inefficiency (TIE). Diagnostic performance was analyzed using a receiver operating characteristic curve. Ten patients were considered as having TE, and five, TIE. Complete non-enhancement was observed in seven ablation zones (70.0%) in the TE group, and peripheral heterogeneous enhancement, in all five ablation zones (100.0%) in the TIE group. The non-enhancement pattern differed significantly between the TE and TIE groups (p = 0.026), with significant correlation with technical efficacy (p = 0.007). The area under the receiver operating characteristic curve was 0.85 (p = 0.008, 95% confidence interval: 0.65-1.05). A non-enhancement pattern using contrast-enhanced ultrasound was useful in the assessment of local efficacy after IRE ablation of pancreatic adenocarcinoma. [ABSTRACT FROM AUTHOR]
Copyright of Ultrasound in Medicine & Biology is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
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DbLabel: Engineering Source
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PubType: Academic Journal
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  Data: Non-enhanced Pattern on Contrast-Enhanced Ultrasound in the Local Efficacy Assessment of Irreversible Electroporation Ablation of Pancreatic Adenocarcinoma.
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  Data: <searchLink fieldCode="AR" term="%22Lin%2C+Manxia%22">Lin, Manxia</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Xie%2C+Xiaoyan%22">Xie, Xiaoyan</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Xu%2C+Ming%22">Xu, Ming</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Feng%2C+Shiting%22">Feng, Shiting</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Tian%2C+Wenshuo%22">Tian, Wenshuo</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Zhuang%2C+Bowen%22">Zhuang, Bowen</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Su%2C+Liya%22">Su, Liya</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Ye%2C+Jieyi%22">Ye, Jieyi</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Lin%2C+Jinhua%22">Lin, Jinhua</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Liang%2C+Ping%22">Liang, Ping</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Yu%2C+Jie%22">Yu, Jie</searchLink><relatesTo>3</relatesTo><br /><searchLink fieldCode="AR" term="%22Kuang%2C+Ming%22">Kuang, Ming</searchLink><relatesTo>1,4</relatesTo><i> kuangm@mail.sysu.edu.cn</i>
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  Data: <searchLink fieldCode="JN" term="%22Ultrasound+in+Medicine+%26+Biology%22">Ultrasound in Medicine & Biology</searchLink>. Sep2018, Vol. 44 Issue 9, p1986-1995. 10p.
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  Data: <searchLink fieldCode="DE" term="%22Ultrasonic+imaging%22">Ultrasonic imaging</searchLink><br /><searchLink fieldCode="DE" term="%22Electroporation%22">Electroporation</searchLink><br /><searchLink fieldCode="DE" term="%22Adenocarcinoma%22">Adenocarcinoma</searchLink><br /><searchLink fieldCode="DE" term="%22Pancreatic+cancer+diagnosis%22">Pancreatic cancer diagnosis</searchLink><br /><searchLink fieldCode="DE" term="%22Diagnosis%22">Diagnosis</searchLink><br /><searchLink fieldCode="DE" term="%22Patients%22">Patients</searchLink>
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  Label: Abstract
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  Data: The objective was to evaluate the diagnostic value of contrast-enhanced ultrasound in the assessment of the local efficacy after irreversible electroporation (IRE) ablation of pancreatic adenocarcinoma 1 mo after ablation. Fifteen patients with pancreatic adenocarcinoma were treated with IRE and then examined by contrast-enhanced ultrasound 1 mo after ablation. The contrast agent was SonoVue. Technical efficacy was assessed at 3 mo after IRE and classified as technical efficiency (TE) and technical inefficiency (TIE). Diagnostic performance was analyzed using a receiver operating characteristic curve. Ten patients were considered as having TE, and five, TIE. Complete non-enhancement was observed in seven ablation zones (70.0%) in the TE group, and peripheral heterogeneous enhancement, in all five ablation zones (100.0%) in the TIE group. The non-enhancement pattern differed significantly between the TE and TIE groups (p = 0.026), with significant correlation with technical efficacy (p = 0.007). The area under the receiver operating characteristic curve was 0.85 (p = 0.008, 95% confidence interval: 0.65-1.05). A non-enhancement pattern using contrast-enhanced ultrasound was useful in the assessment of local efficacy after IRE ablation of pancreatic adenocarcinoma. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
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  Group: Ab
  Data: <i>Copyright of Ultrasound in Medicine & Biology is the property of Elsevier B.V. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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      – Type: doi
        Value: 10.1016/j.ultrasmedbio.2018.05.018
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      – Code: eng
        Text: English
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        PageCount: 10
        StartPage: 1986
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      – SubjectFull: Ultrasonic imaging
        Type: general
      – SubjectFull: Electroporation
        Type: general
      – SubjectFull: Adenocarcinoma
        Type: general
      – SubjectFull: Pancreatic cancer diagnosis
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      – TitleFull: Non-enhanced Pattern on Contrast-Enhanced Ultrasound in the Local Efficacy Assessment of Irreversible Electroporation Ablation of Pancreatic Adenocarcinoma.
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              Text: Sep2018
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