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Physicochemical Stability of Hydroxyapatite-Low-Molecular Polyethylene Glycol 400 Composite Systems in Biological Media.

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Title: Physicochemical Stability of Hydroxyapatite-Low-Molecular Polyethylene Glycol 400 Composite Systems in Biological Media.
Authors: Boshytska, N. V.1 nata25lia@gmail.com, Protsenko, L. S.1, Budilina, O. N.1, Kaplunenko, N. V.1, Minitskiy, A. V.2, Uvarova, I. V.1
Source: Powder Metallurgy & Metal Ceramics. Sep2018, Vol. 57 Issue 5/6, p349-352. 4p.
Subjects: Hydroxyapatite, Polyethylene glycol, Composite materials
Abstract: The physicochemical stability of the composite system consisting of hydroxyapatite (HAP) including 10, 25, and 50% polyethylene glycol (PEG) with a molecular weight of 400 in different physiological solutions has been studied. In the interaction of HAP + PEG 400 composite systems with physiological solutions, the amount of Ca in the filtrate changes versus the PEG content of the composite and the salt composition of the reaction media. The rate of calcium release in Ringer and Ringer-Lokk solutions, whose chemical composition is close to that of the tissue fluid of living organisms, is almost twice as high as in a 0.9% NaCl solution. Chemical analysis has shown that the HAP +10% PEG 400 composite system interacts with physiological solutions and is likely to promote calcium interchange between the experimental material and tissue fluid. Infrared spectroscopy has demonstrated that polyethylene glycol is present in the HAP + 10% PEG system over 120 h of interaction with biological media of living organisms, which will promote the restoration of nervous impulses in the treatment of bone defects. The HAP + 10% PEG 400 composite system can be recommended for further study in the development of novel composite materials for rehabilitation orthopedics. [ABSTRACT FROM AUTHOR]
Copyright of Powder Metallurgy & Metal Ceramics is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Physicochemical Stability of Hydroxyapatite-Low-Molecular Polyethylene Glycol 400 Composite Systems in Biological Media.
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  Data: <searchLink fieldCode="JN" term="%22Powder+Metallurgy+%26+Metal+Ceramics%22">Powder Metallurgy & Metal Ceramics</searchLink>. Sep2018, Vol. 57 Issue 5/6, p349-352. 4p.
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  Data: The physicochemical stability of the composite system consisting of hydroxyapatite (HAP) including 10, 25, and 50% polyethylene glycol (PEG) with a molecular weight of 400 in different physiological solutions has been studied. In the interaction of HAP + PEG 400 composite systems with physiological solutions, the amount of Ca in the filtrate changes versus the PEG content of the composite and the salt composition of the reaction media. The rate of calcium release in Ringer and Ringer-Lokk solutions, whose chemical composition is close to that of the tissue fluid of living organisms, is almost twice as high as in a 0.9% NaCl solution. Chemical analysis has shown that the HAP +10% PEG 400 composite system interacts with physiological solutions and is likely to promote calcium interchange between the experimental material and tissue fluid. Infrared spectroscopy has demonstrated that polyethylene glycol is present in the HAP + 10% PEG system over 120 h of interaction with biological media of living organisms, which will promote the restoration of nervous impulses in the treatment of bone defects. The HAP + 10% PEG 400 composite system can be recommended for further study in the development of novel composite materials for rehabilitation orthopedics. [ABSTRACT FROM AUTHOR]
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  Data: <i>Copyright of Powder Metallurgy & Metal Ceramics is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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