View in EDS HTML Full Text PDF Full Text

Prostate artery embolisation for benign prostatic hyperplasia: a systematic review and meta-analysis.

Saved in:
Bibliographic Details
Title: Prostate artery embolisation for benign prostatic hyperplasia: a systematic review and meta-analysis.
Authors: Malling, B.1 Brian.malling.01@regionh.dk, Røder, M. A.2, Brasso, K.2, Forman, J.3, Taudorf, M.1, Lönn, L.1
Source: European Radiology. Jan2019, Vol. 29 Issue 1, p287-298. 12p. 1 Diagram, 4 Charts, 2 Graphs.
Subjects: Prostate diseases, Hyperplasia, Meta-analysis, Urinary tract infections, Quality of life, Benign prostatic hyperplasia, Arteries, Computed tomography, Prostate, Therapeutic embolization, Systematic reviews, Treatment effectiveness, Diagnosis, Therapeutics
Abstract: Objectives: Prostate artery embolisation (PAE) is a new minimally invasive treatment for lower urinary tract symptoms (LUTS) in men with benign prostatic hyperplasia (BPH). The purpose of this study was to review the efficacy and safety of PAE in the treatment of BPH with LUTS.Methods: A systematic review performed according to the PRISMA guidelines with a pre-specified search strategy for PubMed, Web of Science, Cochrane Library and Embase databases protocol (PROSPERO ID: CRD42017059196). Trials studying the efficacy of prostate artery embolisation to treat LUTS with more than ten participants and follow-up longer than 6 months were included by two independent authors. Outcomes investigated were International Prostate Symptom Score (IPSS), quality of life (QoL), International Index of Erectile Function (IIEF-5), prostate volume (PV), prostate-specific antigen (PSA), peak void flow (Qmax), post-void residual (PVR) and complications. To summarise mean change from baseline, a meta-analysis was done using the random-effects model.Results: The search returned 210 references, of which 13 studies met the inclusion criteria, representing 1,254 patients. Patients in the included studies with data available for meta-analysis had moderate to severe LUTS and a mean IPSS of 23.5. Statistically significant (p value < 0.05) improvements of all investigated outcomes were seen at 12-month follow-up. Major complications were reported in 0.3% of the cases.Conclusions: Our findings suggest that PAE can reduce moderate to severe LUTS in men with BPH with a low risk of complications.Key Points: • Prostate artery embolisation (PAE) improved International Prostate Symptom Score (IPSS) by 67%. • Major complications after PAE are very rare. • Use of cone-beam CT may reduce risk of non-target embolisation. [ABSTRACT FROM AUTHOR]
Copyright of European Radiology is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: egs
DbLabel: Engineering Source
An: 133531109
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Prostate artery embolisation for benign prostatic hyperplasia: a systematic review and meta-analysis.
– Name: Author
  Label: Authors
  Group: Au
  Data: &lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Malling%2C+B%2E%22&quot;&gt;Malling, B.&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;i&gt; Brian.malling.01@regionh.dk&lt;/i&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22R&#248;der%2C+M%2E+A%2E%22&quot;&gt;R&#248;der, M. A.&lt;/searchLink&gt;&lt;relatesTo&gt;2&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Brasso%2C+K%2E%22&quot;&gt;Brasso, K.&lt;/searchLink&gt;&lt;relatesTo&gt;2&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Forman%2C+J%2E%22&quot;&gt;Forman, J.&lt;/searchLink&gt;&lt;relatesTo&gt;3&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22Taudorf%2C+M%2E%22&quot;&gt;Taudorf, M.&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;AR&quot; term=&quot;%22L&#246;nn%2C+L%2E%22&quot;&gt;L&#246;nn, L.&lt;/searchLink&gt;&lt;relatesTo&gt;1&lt;/relatesTo&gt;
– Name: TitleSource
  Label: Source
  Group: Src
  Data: &lt;searchLink fieldCode=&quot;JN&quot; term=&quot;%22European+Radiology%22&quot;&gt;European Radiology&lt;/searchLink&gt;. Jan2019, Vol. 29 Issue 1, p287-298. 12p. 1 Diagram, 4 Charts, 2 Graphs.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: &lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Prostate+diseases%22&quot;&gt;Prostate diseases&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Hyperplasia%22&quot;&gt;Hyperplasia&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Meta-analysis%22&quot;&gt;Meta-analysis&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Urinary+tract+infections%22&quot;&gt;Urinary tract infections&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Quality+of+life%22&quot;&gt;Quality of life&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Benign+prostatic+hyperplasia%22&quot;&gt;Benign prostatic hyperplasia&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Arteries%22&quot;&gt;Arteries&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Computed+tomography%22&quot;&gt;Computed tomography&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Prostate%22&quot;&gt;Prostate&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Therapeutic+embolization%22&quot;&gt;Therapeutic embolization&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Systematic+reviews%22&quot;&gt;Systematic reviews&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Treatment+effectiveness%22&quot;&gt;Treatment effectiveness&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Diagnosis%22&quot;&gt;Diagnosis&lt;/searchLink&gt;&lt;br /&gt;&lt;searchLink fieldCode=&quot;DE&quot; term=&quot;%22Therapeutics%22&quot;&gt;Therapeutics&lt;/searchLink&gt;
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: &lt;bold&gt;Objectives: &lt;/bold&gt;Prostate artery embolisation (PAE) is a new minimally invasive treatment for lower urinary tract symptoms (LUTS) in men with benign prostatic hyperplasia (BPH). The purpose of this study was to review the efficacy and safety of PAE in the treatment of BPH with LUTS.&lt;bold&gt;Methods: &lt;/bold&gt;A systematic review performed according to the PRISMA guidelines with a pre-specified search strategy for PubMed, Web of Science, Cochrane Library and Embase databases protocol (PROSPERO ID: CRD42017059196). Trials studying the efficacy of prostate artery embolisation to treat LUTS with more than ten participants and follow-up longer than 6 months were included by two independent authors. Outcomes investigated were International Prostate Symptom Score (IPSS), quality of life (QoL), International Index of Erectile Function (IIEF-5), prostate volume (PV), prostate-specific antigen (PSA), peak void flow (Qmax), post-void residual (PVR) and complications. To summarise mean change from baseline, a meta-analysis was done using the random-effects model.&lt;bold&gt;Results: &lt;/bold&gt;The search returned 210 references, of which 13 studies met the inclusion criteria, representing 1,254 patients. Patients in the included studies with data available for meta-analysis had moderate to severe LUTS and a mean IPSS of 23.5. Statistically significant (p value &lt; 0.05) improvements of all investigated outcomes were seen at 12-month follow-up. Major complications were reported in 0.3% of the cases.&lt;bold&gt;Conclusions: &lt;/bold&gt;Our findings suggest that PAE can reduce moderate to severe LUTS in men with BPH with a low risk of complications.&lt;bold&gt;Key Points: &lt;/bold&gt;• Prostate artery embolisation (PAE) improved International Prostate Symptom Score (IPSS) by 67%. • Major complications after PAE are very rare. • Use of cone-beam CT may reduce risk of non-target embolisation. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: &lt;i&gt;Copyright of European Radiology is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder&#39;s express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.&lt;/i&gt; (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=egs&AN=133531109
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1007/s00330-018-5564-2
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 12
        StartPage: 287
    Subjects:
      – SubjectFull: Prostate diseases
        Type: general
      – SubjectFull: Hyperplasia
        Type: general
      – SubjectFull: Meta-analysis
        Type: general
      – SubjectFull: Urinary tract infections
        Type: general
      – SubjectFull: Quality of life
        Type: general
      – SubjectFull: Benign prostatic hyperplasia
        Type: general
      – SubjectFull: Arteries
        Type: general
      – SubjectFull: Computed tomography
        Type: general
      – SubjectFull: Prostate
        Type: general
      – SubjectFull: Therapeutic embolization
        Type: general
      – SubjectFull: Systematic reviews
        Type: general
      – SubjectFull: Treatment effectiveness
        Type: general
      – SubjectFull: Diagnosis
        Type: general
      – SubjectFull: Therapeutics
        Type: general
    Titles:
      – TitleFull: Prostate artery embolisation for benign prostatic hyperplasia: a systematic review and meta-analysis.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Malling, B.
      – PersonEntity:
          Name:
            NameFull: Røder, M. A.
      – PersonEntity:
          Name:
            NameFull: Brasso, K.
      – PersonEntity:
          Name:
            NameFull: Forman, J.
      – PersonEntity:
          Name:
            NameFull: Taudorf, M.
      – PersonEntity:
          Name:
            NameFull: Lönn, L.
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 01
              Text: Jan2019
              Type: published
              Y: 2019
          Identifiers:
            – Type: issn-print
              Value: 09387994
          Numbering:
            – Type: volume
              Value: 29
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: European Radiology
              Type: main
ResultId 1