Experimental and numerical investigation on particle-particle interaction of multi-particle separation in an alternating and repetitive microchannel.
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| Title: | Experimental and numerical investigation on particle-particle interaction of multi-particle separation in an alternating and repetitive microchannel. |
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| Authors: | Cadirci, S.1 cadircis@itu.edu.tr, Ince, D.1, Ghanem, I.1, Birol, S. Z.2, Trabzon, L.1,2, Turhan, H.1 |
| Source: | Microsystem Technologies. Jan2019, Vol. 25 Issue 1, p307-318. 12p. |
| Subjects: | Cell separation, Separation (Technology), Microfluidics, Transverse electromagnetic cells, Computational fluid dynamics |
| Abstract: | Inertial focusing plays a major role in size-based cell separation or enrichment for microfluidic applications in many medical areas such as diagnostics and treatment. These applications often deal with suspensions of different particles which cause interactions between particles with different diameters such as particle-particle collision. In this study, particle-particle interaction in a laminar flow through a low aspect ratio alternating and repetitive microchannel is investigated both numerically and experimentally. It is revealed that particle-particle collision affects high quality particle focusing. computational fluid dynamics simulations are conducted for demonstrating the effect of the flow field in the transverse cross-section on the focusing quality and position. The experiments and simulations both revealed that if the flow is seeded with a mixture of particles of 3.3 and 9.9 µm diameters, the quality of focusing intensity is degenerated compared to the focusing features obtained by particles with a diameter of 9.9 µm solely. The results clearly show that particle-particle collision between the 3.3 and 9.9 µm particles has a negative effect on particle focusing behavior of the 9.9 µm particles. [ABSTRACT FROM AUTHOR] |
| Copyright of Microsystem Technologies is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Engineering Source |
| FullText | Text: Availability: 0 |
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| Header | DbId: egs DbLabel: Engineering Source An: 134079124 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Experimental and numerical investigation on particle-particle interaction of multi-particle separation in an alternating and repetitive microchannel. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Cadirci%2C+S%2E%22">Cadirci, S.</searchLink><relatesTo>1</relatesTo><i> cadircis@itu.edu.tr</i><br /><searchLink fieldCode="AR" term="%22Ince%2C+D%2E%22">Ince, D.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Ghanem%2C+I%2E%22">Ghanem, I.</searchLink><relatesTo>1</relatesTo><br /><searchLink fieldCode="AR" term="%22Birol%2C+S%2E+Z%2E%22">Birol, S. Z.</searchLink><relatesTo>2</relatesTo><br /><searchLink fieldCode="AR" term="%22Trabzon%2C+L%2E%22">Trabzon, L.</searchLink><relatesTo>1,2</relatesTo><br /><searchLink fieldCode="AR" term="%22Turhan%2C+H%2E%22">Turhan, H.</searchLink><relatesTo>1</relatesTo> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Microsystem+Technologies%22">Microsystem Technologies</searchLink>. Jan2019, Vol. 25 Issue 1, p307-318. 12p. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Cell+separation%22">Cell separation</searchLink><br /><searchLink fieldCode="DE" term="%22Separation+%28Technology%29%22">Separation (Technology)</searchLink><br /><searchLink fieldCode="DE" term="%22Microfluidics%22">Microfluidics</searchLink><br /><searchLink fieldCode="DE" term="%22Transverse+electromagnetic+cells%22">Transverse electromagnetic cells</searchLink><br /><searchLink fieldCode="DE" term="%22Computational+fluid+dynamics%22">Computational fluid dynamics</searchLink> – Name: Abstract Label: Abstract Group: Ab Data: Inertial focusing plays a major role in size-based cell separation or enrichment for microfluidic applications in many medical areas such as diagnostics and treatment. These applications often deal with suspensions of different particles which cause interactions between particles with different diameters such as particle-particle collision. In this study, particle-particle interaction in a laminar flow through a low aspect ratio alternating and repetitive microchannel is investigated both numerically and experimentally. It is revealed that particle-particle collision affects high quality particle focusing. computational fluid dynamics simulations are conducted for demonstrating the effect of the flow field in the transverse cross-section on the focusing quality and position. The experiments and simulations both revealed that if the flow is seeded with a mixture of particles of 3.3 and 9.9 µm diameters, the quality of focusing intensity is degenerated compared to the focusing features obtained by particles with a diameter of 9.9 µm solely. The results clearly show that particle-particle collision between the 3.3 and 9.9 µm particles has a negative effect on particle focusing behavior of the 9.9 µm particles. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Microsystem Technologies is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s00542-018-3965-4 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 12 StartPage: 307 Subjects: – SubjectFull: Cell separation Type: general – SubjectFull: Separation (Technology) Type: general – SubjectFull: Microfluidics Type: general – SubjectFull: Transverse electromagnetic cells Type: general – SubjectFull: Computational fluid dynamics Type: general Titles: – TitleFull: Experimental and numerical investigation on particle-particle interaction of multi-particle separation in an alternating and repetitive microchannel. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Cadirci, S. – PersonEntity: Name: NameFull: Ince, D. – PersonEntity: Name: NameFull: Ghanem, I. – PersonEntity: Name: NameFull: Birol, S. Z. – PersonEntity: Name: NameFull: Trabzon, L. – PersonEntity: Name: NameFull: Turhan, H. IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Text: Jan2019 Type: published Y: 2019 Identifiers: – Type: issn-print Value: 09467076 Numbering: – Type: volume Value: 25 – Type: issue Value: 1 Titles: – TitleFull: Microsystem Technologies Type: main |
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