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3D Culture Models of Malignant Mesothelioma Reveal a Powerful Interplay Between Photodynamic Therapy and Kinase Suppression Offering Hope to Reduce Tumor Recurrence.

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Title: 3D Culture Models of Malignant Mesothelioma Reveal a Powerful Interplay Between Photodynamic Therapy and Kinase Suppression Offering Hope to Reduce Tumor Recurrence.
Authors: Spring, Bryan Q.1,2,3 b.spring@northeastern.edu, Kessel, David4 dhkessel@med.wayne.edu
Source: Photochemistry & Photobiology. Jan/Feb2019, Vol. 95 Issue 1, p462-463. 2p.
Subjects: Photodynamic therapy, Cancer chemotherapy, Mesothelioma, Antineoplastic agents, Cell death
Abstract: In this issue, Cramer et al. introduce 3D culture models of metastatic mesothelioma to investigate basic cancer biology and new combination therapies for combating this complex and lethal disease. The results suggest that erlotinib‐enhanced photodynamic therapy could further improve the efficacy of intraoperative light‐activation to mop up residual tumor deposits in the clinic following surgical removal of macroscopic mesothelioma metastases. [ABSTRACT FROM AUTHOR]
Copyright of Photochemistry & Photobiology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Engineering Source
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PubType: Academic Journal
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  Data: 3D Culture Models of Malignant Mesothelioma Reveal a Powerful Interplay Between Photodynamic Therapy and Kinase Suppression Offering Hope to Reduce Tumor Recurrence.
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  Data: <searchLink fieldCode="AR" term="%22Spring%2C+Bryan+Q%2E%22">Spring, Bryan Q.</searchLink><relatesTo>1,2,3</relatesTo><i> b.spring@northeastern.edu</i><br /><searchLink fieldCode="AR" term="%22Kessel%2C+David%22">Kessel, David</searchLink><relatesTo>4</relatesTo><i> dhkessel@med.wayne.edu</i>
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  Data: <searchLink fieldCode="JN" term="%22Photochemistry+%26+Photobiology%22">Photochemistry & Photobiology</searchLink>. Jan/Feb2019, Vol. 95 Issue 1, p462-463. 2p.
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  Data: <searchLink fieldCode="DE" term="%22Photodynamic+therapy%22">Photodynamic therapy</searchLink><br /><searchLink fieldCode="DE" term="%22Cancer+chemotherapy%22">Cancer chemotherapy</searchLink><br /><searchLink fieldCode="DE" term="%22Mesothelioma%22">Mesothelioma</searchLink><br /><searchLink fieldCode="DE" term="%22Antineoplastic+agents%22">Antineoplastic agents</searchLink><br /><searchLink fieldCode="DE" term="%22Cell+death%22">Cell death</searchLink>
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  Label: Abstract
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  Data: In this issue, Cramer et al. introduce 3D culture models of metastatic mesothelioma to investigate basic cancer biology and new combination therapies for combating this complex and lethal disease. The results suggest that erlotinib‐enhanced photodynamic therapy could further improve the efficacy of intraoperative light‐activation to mop up residual tumor deposits in the clinic following surgical removal of macroscopic mesothelioma metastases. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
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  Data: <i>Copyright of Photochemistry & Photobiology is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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        Value: 10.1111/php.13059
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      – Code: eng
        Text: English
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        PageCount: 2
        StartPage: 462
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      – SubjectFull: Photodynamic therapy
        Type: general
      – SubjectFull: Cancer chemotherapy
        Type: general
      – SubjectFull: Mesothelioma
        Type: general
      – SubjectFull: Antineoplastic agents
        Type: general
      – SubjectFull: Cell death
        Type: general
    Titles:
      – TitleFull: 3D Culture Models of Malignant Mesothelioma Reveal a Powerful Interplay Between Photodynamic Therapy and Kinase Suppression Offering Hope to Reduce Tumor Recurrence.
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            – D: 01
              M: 01
              Text: Jan/Feb2019
              Type: published
              Y: 2019
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